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J Teichman

Publications and source records attributed to J Teichman.

8 recordsLinked to original sources
PubMed1993

A survey of lead contamination in soil along Interstate 880, Alameda County, California.

This study was undertaken to determine the levels of lead in soils taken from yards of homes in close proximity to a major freeway. Soils were collected from the yards of homes in communities adjacent to the freeway and within a 1-mile radius. Samples were analyzed using U.S. Environmental Protection Agency (EPA) methods and atomic absorption instrumentation. Ten percent of the samples were split and sent to a second laboratory for quality control. The possibility of lead-based paint contributing to the contamination was eliminated by sampling more than 20 feet from the homes. The soils closest to the highway showed lead levels exceeding California's and EPA's criteria for hazardous waste. A stratified sample of the depth of contamination in soils was also undertaken. Previously identified "hot spots" (soils with lead levels exceeding 500 ppm in the top 0.75 inch) were core sampled. Results indicated 90% of the subsurface samples contained lead exceeding the surface contaminations. This may be attributed to decades of urban lead-laden dust deposition. As the use of leaded gasolines have diminished in the past decade, the uppermost layers of soil/dust contained lower amounts of lead.

Automobiles↗
PubMed1983

Influence of danazol on cytoplasmic and nuclear estrogen binding capacity in the uterus.

Sprague-Dawley rats with estrous cycles were exposed to danazol (Danocrine) at a single dose of 10 mg/kg for either 6 or 24 hours, or daily until a pattern of no cycles (6 days) was noted on vaginal smears. The animals were individually housed and exposed to a 14-hour light/10-hour dark environment. Prior to drug administration, daily vaginal smears were obtained to ensure cycle normalcy. After the appropriate exposure to medication, the animals were killed, the uterine horns were removed, and determination was made of cytoplasmic and nuclear estrogen receptors. The animals in the control group (6 and 24 hours, and daily injected) received vehicle only (mineral oil). The influence of danazol on sex-steroid receptor levels appeared to be related to the phase of the estrous cycle at the time of sacrifice. At both 6 and 24 hours of exposure to danazol, there was a slight decrease in specific estrogen binding capacity of cytosols, with no alteration in the levels of nuclear receptors in the uteri of rats with cycles. In the groups with no cycles, there was an increase in cytosolic estrogen binding capacity at 1 and 6 days of danazol treatment, with a slight decrease in nuclear receptor binding when compared with treated rats with cycles. Statistical evaluation revealed a significant difference in cytosolic estrogen binding capacity between the series with cycles and the series without cycles (p less than 0.01). This study provides further information in regard to danazol action on cytosol and nuclear receptors correlated with phase of the estrous cycle.

Animals↗
PubMed1983

Influence of certain prostaglandin synthetase inhibitors on cytoplasmic estrogen receptors in the uterus.

Prostaglandin synthetase inhibitors are widely used in the treatment of primary dysmenorrhea. They are thought to act by inhibiting endometrial synthesis of prostaglandins and subsequently altering endometrial receptor concentration. Since prostaglandins are known to vary with the menstrual cycle in women, implicating an effect associated with sex steroid hormones, we examined the influence of certain prostaglandin synthetase inhibitors on specific estrogen binding capacity of uteri from rats. Ibuprofen (Motrin), 25 mg/kg, indomethacin (Indocin), 15 mg/kg, mefenamic acid (Ponstel), 25 mg/kg, and sulindac (Clinoril), 40 mg/kg, were evaluated at 6 and 24 hours after injection. Specific estrogen-binding capacity was elevated twofold by mefenamic acid; the other agents showed no statistically significant effect. No alteration in the dissociation constant values of the estrogen receptors was observed with these agents. These data suggest that prostaglandin synthetase inhibitors do not influence the estrogen response mechanism in rodents.

Animals↗
PubMed1982

Illegitimacy.

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Family Planning Services↗
PubMed1978

Separation of polychlorobiphenyls from chlorinated pesticides in sediment and oyster samples for analysis by gas chromatography.

Polychlorobiphenyls (PCBs) have been separated from DDT and its analogs and from the other common chlorinated pesticides by adsorption chromatography on columns of alumina and charcoal. Elution from alumina columns with increasing fractional amounts of hexane first isolates dieldrin and heptachlor epoxide from a mixture of chlorinated pesticides and PCBs. The remaining fraction, when added to a charcoal column, can be separated into two fractions, one containing the chlorinated pesticides, the other containing the PCBs, by eluting with acetone-diethyl ether (25:75) and benzene, respectively. The PCBs and the pesticides are then determined by gas chromatography on the separate column eluates without cross interference. The method is applicable to sample extracts prepared for gas chromatography. Recoveries of the PCBs (Aroclors) and the chlorinated pesticides are good and the method is applicable to sediment and marine biota samples.

Chromatography, Gas↗