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Biomedical subjects

J Terho

Publications and source records attributed to J Terho.

7 recordsLinked to original sources
PubMed1987

Effective contraception with the levonorgestrel-releasing intrauterine device: 12-month report of a European multicenter study.

The use-effectiveness of an intrauterine contraceptive device releasing 20 mcg of levonorgestrel daily (Lng-IUD), and of a Nova T copper-releasing IUD, were studied in a randomized, comparative multicenter trial. The Lng-IUD was inserted in 1821, and the Nova T in 937 women. The 12-month net pregnancy rate with the Lng-IUD (0.1 per hundred women) was significantly lower than that with the Nova T (0.9 per hundred). Removal rates for menstrual problems and/or pain were similar for the two methods (net rates 7.5 and 8.7, respectively). The 12-month continuation rates were 82.2 for the Nova T and 79.7 for the Lng-IUD. The reduction of the bleeding led to oligomenorrhea and amenorrhea in users of the Lng-IUD; the removal rate for these reasons was 1.4. The removal rate for hormonal side effects with the Lng-IUD was 2.4. Blood hemoglobin concentrations increased among users of the Lng-IUD and decreased among users of the Nova T. The results show that the Lng-IUD was a highly effective contraceptive method which reduced menstrual bleeding. It is a promising alternative for women desiring a highly effective method for long-term use.

Adult↗
PubMed1975

[Cervical status and subjective symptoms in the normal pregnancy].

In 426 unselected pregnant women who came into the routine examination included in the maternity care and who were grouped according to the week of gestation the cervical status was examined and the subjective symptoms were observed. Attention was also paid to the correspondence between the occurrence of the subjective symptoms and the change in the cervical status. In total 984 examinations were carried out. Before the 33rd week of gestation no open internal orifice of the cervix uteri were found. All parities in total the cervix had become shorter (less than or equal to 2 cm) in 7,0 per cent of the cases before the 33rd week of gestation. Subjective symptoms occurred in 19,1 per cent of the cases. Towards the end of the gestational period the changes in the cervical status and the subjective symptoms became more frequent. In all the groups of gestational week the cervical status became pathologic significantly more frequently in pregnancies with subjective symptoms than in pregnancies with no symptoms.

Cervix Uteri↗
PubMedDate not supplied

Smoking does affect fecundity.

A total of 2198 mothers were interviewed at the 20th week of pregnancy and their smoking habits before pregnancy and the time from discontinuation of contraception to the beginning of the pregnancy were registered. This information was used to investigate whether smoking affects conception delay; i.e., fecundity and a multifactorial analysis were used. The longer the conception delay, the more significant was the deleterious effect of even light smoking, the odds ratio shifting from 1.1 at 6 months to 3.2 at 18 months. The effect of smoking on fecundity seemed to be mostly dose-dependent. In mothers becoming successfully pregnant in 12 months, both maternal and paternal smoking increased the risk of conception delay (OR 1.5 and 1.3), and the effect was potentiated by increasing age (OR 2.3 and 1.6). In addition to smoking, previous recurrent spontaneous abortions were also associated with fecundity.

Alcohol Drinking↗