PubMed Health⌕ Search

Biomedical subjects

J Thygesen

Publications and source records attributed to J Thygesen.

At least 19 recordsLinked to original sources
PubMed2000

[Glaucoma patients treated by practicing ophthalmologists in Denmark. Estimated number of patients and the extent of visual field defects].

A test survey based on a questionnaire was carried out among Danish eye practitioners. The response rate was 72%. The purpose was to estimate the minimum number of patients suffering from glaucoma (prevalence). Survey results show a prevalence of 0.65%. Further, the survey shows a clear correlation between glaucoma diagnosis and age. The number of glaucoma patients increase from approximately 0.5% for persons 50 years of age to approximately 5% for persons 80 years of age. Seventy-two percent of the diagnosed glaucoma patients have visual field defects at different stages. Six percent have central islands on both eyes, the equivalent of a prevalence for social blindness of 0.04%. Ninety-three percent of the diagnosed glaucoma patients receive anti-glaucomatous treatment, of these 42% combination therapy. Eighty percent of glaucoma patients in combination therapy received three or more drugs.

Adult↗
PubMed2000

Short-term effect of latanoprost and timolol eye drops on tear fluid and the ocular surface in patients with primary open-angle glaucoma and ocular hypertension.

PURPOSE: To investigate and compare the short term effects of topical latanoprost and timolol on the tear fluid and ocular surface condition in patients with bilateral primary open angle glaucoma or ocular hypertension. METHODS: Thirty-seven patients were included in this randomized, double-masked, parallel group study. Patients received either latanoprost 0.005% (n= 18) or timolol 0.5% (n= 19) instilled once daily in the morning for a treatment period of 27 days. Routine ophthalmic examinations, including intraocular pressure measurement, as well as tests to evaluate tear fluid and the ocular surface were performed. RESULTS: After one drop of medication, tear secretion was significantly reduced by timolol, but not by latanoprost. At the end of the study the break-up time (BUT) was significantly decreased in the timolol group but not in the latanoprost group. The BUT still remained in the normal range in both groups, although it is important to note that timolol was administered at half the clinical dose. Both latanoprost and timolol tended to increase Rose-Bengal staining of the cornea and conjunctiva after one month of treatment but no statistically significant difference was found between the groups. Corneal sensitivity was within the normal range for all patients during the study. CONCLUSION: Regarding ocular surface effects, no clinically important differences between latanoprost and timolol were observed as all the effects remained in the normal range.

Adrenergic beta-Antagonists↗
PubMed1999

[Two cases of severe eye and cranial injuries due to firework explosions].

Two patients who sustained serious facial, cranial and eye trauma secondary to recreational fireworks injuries are reported. Initial assessment included axial and coronary computerized tomography, control of haemorrhage, debridement of wound and brain, and in one patient bilateral excenteration of the globe. Both patients suffered from intracranial haemorrhage, but both recovered without severe neurological sequelae.

Adult↗
PubMed1979

Corneal astigmatism after cataract extraction. A comparison of corneal and corneoscleral incisions.

Corneal astigmatism after cataract surgery by way of corneal incision (C, n = 62) and corneo-scleral incision (CS, n = 61) was followed for six months. Corneal incisions were closed by continuous nylon 10--0 (7--25 loops, median 14). Corneo-scleral incisions were sutured with single knots (2--10, median value 5). Keratometric results in the C and CS groups are compared. Concerning the degree of astigmatism, pre-operative median values were 0.5 and 0.7 D, respectively. After one week they were 4.5 and 3.0 D; after two weeks 3.3 and 3.0 D; after four months 3.0 and 2.0 D; after six months (final status) 1.5 and 1.7 D, respectively. The differences between C and CS were not significant. For both, astigmatism after cataract surgery did not quite return to pre-operative levels. Concerning the axis (weaker meridian) of corneal astigmatism, the C cases retained their pre-operative distribution, while the CS cases showed the classical shift towards against-rule astigmatism. Final corrected visual acuity was of the same order in the C and CS group. Due to frequent shifts, also of the axis, it is recommended by early (preliminary) glass prescription not to correct the astigmatism, but to give only the best spherical correction.

Adult↗