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Biomedical subjects

J Tokarski

Publications and source records attributed to J Tokarski.

7 recordsLinked to original sources
PubMed1992

The influence of immobilization stress on natural killer cytotoxic activity in halothane susceptible and resistant pigs.

In halothane-susceptible (Hal+) and halothane-resistant (Hal-) Belgian Landrace pigs, the influence of immobilization stress on cytotoxic activity of natural killer (NK) cells was evaluated. Four hour immobilization causes biphasic changes in cytotoxicity, i.e. an initial increase followed by a subsequent depression. In both groups of pigs stress-induced suppression of NK cell activity lasted for several days in the post stress period. Throughout the experiment, i.e. before, during and after stress, the level of cytotoxicity was higher in Hal+ than in Hal- pigs.

Animals↗
PubMed1989

Differential effect of the damage to the lateral hypothalamic area on hippocampal theta rhythm during waking and paradoxical sleep.

Hippocampal theta rhythm was analyzed in rats subjected to bilateral, electrolytic lesions of the lateral hypothalamic (LH) region at different levels of its rostro-caudal axis. It was found that damage to the LH disturbed the hippocampal theta activity both during waking and paradoxical sleep. The main effect consisted in the lowering of the theta frequency. Typically, a decrease of frequency was accompanied by an increase of amplitude during waking, and an amplitude fall during paradoxical sleep. Extensive lesions increased the amount of rhythmic slow activity during waking and induced long trains of immobility-related theta. The general picture of impairments of the hippocampal theta rhythm in particular subjects depended on the size of the lesion and, to some extent, also on its localization within the LH. It is concluded that LH region contains systems of fibers which transmit impulses from the brain stem reticular formation to the prosencephalic structures generating the rhythmicity of theta.

Animals↗
PubMed1976

The behaviour of acetylcholinesterase activity in neurons of the bulbous part of the reticular formation in albino rats after bilateral vagotomy.

The influence of a bilateral vagotomy on the acetylcholinesterase activity (AChE) in the neurons of the bulbous part of the reticular formation of albino rats was investigated. An increase in the reaction to acetylcholinesterase (AChE) was ascertained in the large as well as the small neurons 8 h after the transection of the vagus nerves, which indicates their decreased activity. It may be assumed that a bilateral vagotomy causes a decrease in the activity of cholinergic mechanisms within the periphery of the reticular formation neurons.

Acetylcholinesterase↗
PubMedDate not supplied

The EEG activity after lesions of the diencephalic part of the zona incerta in rats.

Neocortical and hippocampal EEG activity was recorded in 23 rats subjected to the bilateral electrolytic lesions of the diencephalic zona incerta (ZI). The aim was to find whether damage to ZI can replicate insomnia and disturbances in cortical EEG desynchronization and hippocampal theta rhythm found after lesions of the lateral hypothalamic (LH) area. No effect of the ZI lesions on waking-sleep cycle was found. The amplitude and frequency of cortical waves and hippocampal theta rhythm during waking were changed only in some rats. These changes were small, short-lasting and bidirectional (toward and increase or decrease in different subjects). Both the amplitude and frequency of paradoxical sleep theta were depressed in part of animals. Thus the marked EEG changes after LH lesions can not be attributed to simultaneous damage of the adjacent subthalamic region. However, the ZI seems to constitute a part of a larger system regulating cortical arousal and hippocampal theta rhythm.

Animals↗
PubMedDate not supplied

[Meningomyelocele with spinal cord cyst and internal hydrocephalus in a 9-month-old boy].

The authors describe a boy aged 9 months with open myelomeningocele which changed gradually into meningocele with spinal cord cyst. During treatment internal hydrocephalus developed requiring insertion of Pudenz-Heyer ventriculoatrial. valve. The treatment was successful. The case illustrates the succession of changes which may develop in myelomeningocele and the relationship between the state of internal hydrocephalus and the volume of meningocele and spinal cyst (cerebrospinal fluid production exceeding its resorption).

Cysts↗
PubMedDate not supplied

A programming unit for prolonged, cyclic stimulation.

A system is described allowing for automatization of prolonged frequently repeated stimulation with independent control of individual stimulation time and intervals between consecutive stimulations. Through a controlling system of electromagnetic relay it was possible to obtain bipolar mechanical isolation of the stimulator from the electrodes during intervals between sucessive stimulations which eliminated sompletely the possibility of uncontrolled stimulation of the preparation.

Electric Stimulation↗