Failure of renal renin depletion without forced diuresis to protect rats against HgCl2-induced acute renal failure.
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Biomedical subjects
Publications and source records attributed to J Torhorst.
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Morphology and growth characteristics of an osteosarcoma and a glioblastoma are described after direct transplantation in nude (thymusless) mice. In osteosarcoma neither characteristic had changed after 14 months' observation. In contrast, some of the glioblastoma transplants (22 months' observation) showed dedifferentiation of morphology and grew faster than others derived from the same biopsy. The possible reasons for the different growth pattern of the two tumors are discussed.
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A case of fatal graft-versus-host disease (GvHD) following blood transfusions is reported. This relatively rare complication of blood and bloodcomponent replacement therapy may occur in recipients with decreased cellular immunity, which may be due to the underlying disease, chemotherapy or radiation therapy, or a combination of both. GvHD is a result of active proliferation of transfused immunologically competent cells which attack host organs. This complication can be prevented by irradiating transfusions with 1500 rads in vitro.
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