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Biomedical subjects

J Traserra

Publications and source records attributed to J Traserra.

At least 19 recordsLinked to original sources

[Bilateral chylothorax after radical neck dissection. Apropos of a case].

Bilateral chylothorax following radical neck dissection is an uncommon complication of head and neck surgery. Only 9 more cases have been reported in the English literature until now. Early recognition is not difficult if it is bear in mind when evaluating dyspnoeic patients with bilateral pleural effusions after neck dissection. In this paper the authors report their experiences with a case and comment on the treatment employed. The authors believe that due to its potential severity, it must be considered when ever head and neck surgery is performed.

Chylothorax

[The incidence of the inappropriate ADH secretion syndrome (SIADH) in major otorhinolaryngologic surgery].

There are few works dealing with the presentation of the inadequate secretion of antidiuretic hormone in major ENT procedures. In this prospective study done by the AA., based in analytic data, they found out the presence of the syndrome in as many as 39 percent of those operations. Consequently the suggestion is made that major ENT-surgery must be considered among the potential factors of the syndrome.

Age Factors

[Thornwaldt's cyst. The experience of a decade].

The cyst of the Thornwaldt's bursa is a bulge on the postero-superior wall of the rhinopharynx, due to the closure of the sac's drainage duct. The bursa pharyngea being an embryologic remnant occurring in 3 percent of healthy adults. It is a process well known since a century, but only 11 cases (in 9 several publications) have been quoted in the last 20 years. Perusal of the cases seen at the ENT Department of the Clinic and Provincial Hospital of Barcelona during the latter decade.

Adolescent

[Incidence of Borrelia burgdorferi infection in isolated facial paralysis. A prospective study].

Between the causes of facial paralysis, similar to Bell's palsy, recently are included those due to some families of spirochaeta (Borrelia burgdorferi) transmitted through tick-bite. These bacteria, besides de facial palsy, may produce several degrees of lymphocytic meningitis and subsequently the paralysis of the face, sometimes clumsy or recurrent. The treatment being the antibiotic drugs, never the corticoids. In the paper are explained prospectively the incidence of this disease in the AA's environment.

Adolescent

[Ototoxicity of deferoxamine].

Deferoxamine or desferrioxamine (DFO) is a chelating agent, largely used in patients with chronic renal failure, although it has many side effects, being ototoxicity one of them. In this paper we studied the eventually adverse otologic effects of DFO in 20 patients receiving haemodialysis. A complete audiological evaluation, including pure-tone audiometry, brainstem auditory evoked potentials and high-frequency audiometry, was performed. The results showed a sensorineural hearing loss of retrocochlear origin in 3/20 cases (15%). We can accept that ototoxic effects of DFO are minimal, but no inexistent. Because of these we considered highly recommendable an accurate control of hearing in patients with renal disease receiving DFO.

Adult

Non-Hodgkin's lymphomas of nasal cavity and paranasal sinuses. An immunohistochemical study.

The authors studied the immunophenotype of nine sinonasal lymphomas using a panel of monoclonal antibodies that react with fixed, paraffin-embedded material (EMA, CAM 5.2, CD45, CD37 [MB-1], MB-2, L-26, CDw75 [LN-1], CD45RA [4 KB-5], CD43 [MT-1], and CD45RO [UCHL-1]). There were seven men and two women, with a mean age of 64 years (range, 9-89 years) and median age of 56 years. Three tumors were limited to the nasal cavity, and the other six had multiple sites of involvement, including the nasal cavity (five), antrum (six), ethmoid (two), orbit (two), and hard palate (one). Histologically, one was a lymphoblastic lymphoma (LBL), one was small cleaved-cell lymphoma (SCCL), three were mixed-cell lymphomas (MCLs), and four were large cell lymphomas (LCLs). Four cases were T-cell lymphomas (one SCCL, three MCLs), four were B-cell neoplasms (four LCLs), and one was of uncertain lineage (LBL). Angioinvasion, coagulative necrosis, and epitheliotropism were seen in the T-cell lymphomas. Extranasal dissemination was seen in four cases: one LBL that involved the lymph nodes, skin, and testes 15 months after diagnosis; one B-LCL that involved the skin 9 months after diagnosis; and one B-LCL and one T-MCL that involved the gastric mucosa and lung simultaneously with nasal presentation. This study shows a higher predominance of B-cell lymphomas in the sinonasal region than previously reported in Oriental populations. However, the T:B ratio of these lymphomas is still greater than that observed for primary lymph node-based neoplasms.

Adolescent

Asymptomatic electronystagmographic abnormalities in patients with type I diabetes mellitus.

Only a few studies have investigated vestibular function in diabetes mellitus (DM), showing contradictory results. We have performed an electronystagmographic (ENG) evaluation of 46 individuals with type I DM and 37 healthy controls. No patient reported subjective vestibular symptoms. Duration of caloric-induced nystagmus (DN) was significantly lower (2.1 +/- 0.7 vs. 2.6 +/- 0.4 min, p less than 0.01), and central nystagmus frequency of caloric response also nonsignificantly tended to be decreased (37.4 +/- 16.5 vs. 41.7 +/- 12.7 beats/30s, p = 0.21) in DM patients, as compared to controls. The latter comparison achieved significance after exclusion of newly diagnosed diabetic patients (33.4 +/- 16.1 vs. 41.6 +/- 12.7 beats/s, p less than 0.05). Depressed caloric reactions were seen in 21.8% of patients. DN was lower in patients with microalbuminuria and retinopathy, but this was not observed after exclusion of newly diagnosed diabetic patients, all of whom had normal ENG responses and no chronic diabetic complications. The existence of a lower DN and central nystagmus frequency should be borne in mind when interpreting ENG tracings in patients with long duration type I diabetes mellitus.

Adolescent

[Auditory evoked potentials in chronic alcoholism].

Prospective study of about 42 chronic alcoholics and evaluation, by means of auditory evoked potentials, of their auditive pathways. Checking of the damage at the outmost degree of the pathway, in alcoholic encephalopathy. Discussion and evaluation of the tracings.

Adult

[Cervical seminoma. Presentation of a case].

A germinal cells tumor in a male manifested as left supraclavicular mass, without other localisation, is presented. The pathologic anatomy corroborate the diagnosis of seminoma. Very few cases of a germinal cell tumor in the supraclavicular fossa, with a normal testicular exploration, have been reported.

Adult

[Cholesteatoma of the paranasal sinuses. Apropos of 2 cases].

Two cases of cholesteatoma of the facial sinuses are presented. One of them was located in the maxillary sinus and the other was originally located in the ethmoid cells and extended into the maxillary sinus. After reviewing the literature on this subject, the authors analyze the pathogenetic theories and the clinicoradiological expressions. These raise an obvious diagnostic difficulty: the diagnosis is virtually impossible to establish before surgery and a clinicopathological study are performed.

Aged

Esophageal foreign bodies in adults.

We present our 1-year experience in the management of esophageal foreign bodies in 31 adult patients, and we analyze the predisposing and risk factors, the diagnostic procedures, the removal techniques and the postoperative control and treatment.

Dentures

Sensorineural high-frequency hearing loss after drill-generated acoustic trauma in tympanoplasty.

Tympanoplasty can cause a sensorineural hearing loss by a mechanism of acoustic trauma. Although this lesion appears to be relatively infrequent in clinical practice, we believe that its low apparent incidence is caused when clinicians fail to assess the auditory frequencies above 8000 Hz. Twenty-four patients with normal bone-conduction audiometric thresholds scheduled for tympanoplasty were assessed with an electro-stimulation, bone-conduction high-frequency audiometer which can measure hearing frequencies up to 20 kHz before and after surgery. A measurable hearing loss was found in the upper limits of the audible frequencies in 9 patients (37.5%), and was considered important in 4 of them (16.7%). This hearing loss was recorded above the upper frequency limit of conventional audiometers. The findings in this study indicate that drilling of the temporal bone can impair the hearing level in the high frequencies in a significant number of patients. High-frequency audiometry is a very sensitive tool to assess any damage caused to the inner ear by surgical procedures carried out in the middle ear and temporal bone.

Adolescent

[Characteristics of the course of glottic cancer].

We present a retrospective study of the course of glottic cancer in a series of 302 cases. We studied the precise tumour localisation, the treatment carried out, the anatomico-pathological characteristics of the resected tissue and the results obtained as a function of the therapy used. It would seem important to stress the necessity of homogenizing the results of various authors by: presenting a series large enough for the results to be significant; there should be detailed total and prolonged follow up of patients, with use of similar evaluation parameters.

Glottis

[The intensity of tinnitus].

The AA. intend to find a significant relationship between the subjective intensity of the tinnitus experienced by 47 patients, as assessed by themselves from a 7-point scale, and the objective intensity evaluated by audiometric matching of the noise. The relationship among the subjective intensity, the frequency of tinnitus and the hearing loss at the same frequency of the tinnitus aurium has also been studied. A statistically significative relationship between these parameters could not be possible find out. So they think necessary to find some others means to assess the intensity of the tinnitus.

Adult

Sudden hearing loss in an adolescent following a single dose of cisplatin.

Progressive hearing loss after cisplatin therapy is relatively frequent, specially in older patients, but it is less common in children and in acute form. The case of a 17-year-old patient with an intracranial tumor who suffered sudden deafness after a single course of cisplatin is presented. This patient had a previously documented very good hearing up to 20 kHz. Although it has been suggested that children with irradiated brain tumors may have an increased susceptibility to cisplatin-induced hearing loss, in this case the patient had not been subjected to radiotherapy.

Adolescent