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Biomedical subjects

J Trnka

Publications and source records attributed to J Trnka.

At least 19 recordsLinked to original sources

[Classification of acute pancreatitis in correlation with serum protease levels].

Based on previous work of their own and data in the literature the authors outlined diagnostic and classification criteria of acute pancreatitis. The latter were applied in a prospective study. Thus a group of 71 patients with acute pancreatitis was obtained. In 10 patients of this group at the same time intervals and while the same therapeutic procedures were used, the serum protease levels were followed up. The authors assumed that it will be possible to express thus objectively the severity of the disease and to diagnose in time necrotizing forms of acute pancreatitis. The results re demonstrated the feasibility and suitability of this procedure only for assessment of the severity of the disease.

Acute Disease

Systematized progradient multiple combined melanocytic and blue nevus.

A 44-year-old woman was diagnosed as having unilateral multiple progradient pigmented macules and papules of the upper extremity and adjacent part of the back. Microscopically increased amounts of melanin and melanocytes in the basal layer of the epidermis in the early developmental stage of macules were seen. Combinations of blue nevus with junctional or compound nevus or with a simple proliferation of melanocytes in the epidermis were present in the papules. The question of prognosis is discussed.

Adult

[Dermatology in Prague and the 1st Congress of the German Dermatology Society 1889].

Around 1900, dermatology as practised in Prague formed a link between Austria and Germany. The Congress of the German Dermatological Society held in 1889 in Prague was the first highlight of this connection. The topics and contents of the papers are characterized. The development of the dermatological clinics in Prague is described and their directors and research emphases are listed.

Czechoslovakia

[Dissimulated dermatozoon delusion with severe skin artifacts].

A 37-year-old civil servant, who had been treated for 9 years for sycosis simplex, covered up the presence of his dermatozoon delusion, which had probably only developed in the course of time since the original diagnosis had been made. In a single examination performed when he was referred to our clinic, he admitted for the first time that he had been using sharp objects to dig out ingrown beard hair and mites. This practice had caused numerous sclerotic scars and ulcers on the facial skin. In our dermatological practice, this was an unusual finding in a patient with a dermatozoon delusion.

Adult

Results of screening for phenylalanine and other amino acid disturbances among pregnant women.

Blood specimens were collected from 15000 pregnant women during the first 3 months of their pregnancy and screened for amino acid disturbances by means of paper chromatography. A high incidence of disturbances in the phenylalanine metabolism was discovered: three cases of mild hyperphenylalaninaemia without phenylpyruvicaciduria (incidence 1:5000); two cases of mild hyperphenylalaninaemia with phenylpyruvicaciduria (incidence 1:7550); four cases of mild phenylketonuria (incidence 1:3750). Disturbances in the metabolism of other amino acids were found to be rare. Metabolic and genealogical findings in some detected families are briefly described.

Adult