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Biomedical subjects

J Tsutsui

Publications and source records attributed to J Tsutsui.

At least 55 records · Page 3Linked to original sources

Dynamic topography of visual evoked potentials and extrageniculate projection in case of Riddoch phenomenon.

A 34-year-old woman showing the Riddoch phenomenon was studied by the technique of dynamic topography of visual evoked potential (VEP). This case had cortical blindness which developed during the process of massive intestinal hemorrhage, shock and surgery. The visual acuity was limited to hand movement, and perception of white and colored light was present, but there was no form recognition. Tracking eye movement for a flashlight was possible and optokinetic nystagmus (OKN) also appeared. CT-scan showed a diffuse low density area in the white matter of the occipital lobe. The VEPs by flash and a checkerboard of 60'-100' were detectable. Dynamic topography of the VEP showed that a strong negative deflection from the brainstem appeared at around 30 msec and this deflection expanded to the parietal region at about 90 msec. Subsequently, a positive deflection extending from the frontal region to the occipital region continued at 100 msec to 150 msec. Such a process of reaction is not observed in the normal subject. These findings suggest that the visual reaction was conducted abnormally through the extrageniculate system; from the brainstem to the parietal area and then to the occipital area.

Adult↗

Average responses evoked by moving grating pattern in the upper, central and lower visual field.

Detectable visual evoked potentials were obtained in man by stimulation in the peripheral visual field with a 0.4 cycle/deg vertical grating pattern of 5 degrees arc subtense which moved twice per second horizontally at 415 degrees/sec through an amplitude of 8 degrees arc. These moving grating stimuli were presented to 10 normal subjects, centered 15 degrees above, or centered around, or centered 15 degrees below a fixation mark. The mean latencies (+/- S.D.) of the positive component of the potential evoked by stimuli to the central and 15 degrees eccentricity lower visual field were 114 +/- 17 msec and 104 +/- 20 msec, respectively, while latencies for 15 degrees eccentricity upper visual field stimuli were significantly (p less than 0.001) later with 148 +/- 20 msec.

Adult↗

[Bilateral direct injury of oculomotor nerves in craniocerebral trauma-report of a case (author's transl)].

A 46-year-old housewife was admitted to the Kawasaki Hospital soon after traffic accident. She was struck in the right forehead. She was very slightly drowsy but well oriented. Both eyeballs were extremely abducted without any motility. The pupils were bilaterally dilated and equal in size with no response to light. There was a pronounced blephaloptosis on both sides. Another neurological abnormality was a slight right facial weakness. On skull films, a linear fracture in the right temporobasal region was noted but the views of the orbits were normal. A lumbal tap showed a mild subarachnoidal hemorrhage. Three weeks after the trauma, pneumoencephalography showed no abnormal finding. Throughout convalescence, no special treatment was given beyond medication. She improved steadily. Three years after injury, re-examination disclosed that lateral gaze was almost full to either side but upward and downward movements of both eyeballs were limited. In our opinion, the most likely cause of the disability in this case was bilateral direct damage of the oculomotor nerves near the petroclinoid ligament (Grüber).

Brain Injuries↗