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Biomedical subjects

J Tyberghein

Publications and source records attributed to J Tyberghein.

At least 19 recordsLinked to original sources
PubMed1996

Presbycusis and phonemic regression.

One thousand forty two tonal and speech audiograms are compared to the results of Jerger's speech audiometry (Synthetic Sentence Identification). In older subjects (more than 50 years) with a normal PTA or with a high frequency hearing loss, the speech intelligibility is better in a silent than in a noisy environment where it is a function of the Speech reception threshold. This difference is much smaller in younger individuals. In subjects with a horizontal Pure Tone Audiogram (PTA) (between 20 and 60 dB) the speech intelligibility is almost the same in a silent or a noisy environment for both age groups. An important part of phonemic regression in the elderly probably can be explained by pathology of the organ of Corti and the first cochlear neuron.

Adult↗
PubMed1993

The effects of ventilation tube placement on hearing, speech, language, cognition and behaviour.

As a part of a larger, multidimensional study on secretory otitis media (SOM) and its relation to children's development, the effects of ventilation tube (VT) placement on hearing, speech, language, cognition and behaviour were studied over a six month period. Children with a clear and persistent picture of SOM were examined just before tubes were inserted and again, with the same measures, six months later. Their evolution was compared to that of a control group. The results indicate, as was expected, that the hearing of the children with SOM normalized very quickly after surgery. Speech and expressive language functions were comparable for both groups at the two moments of examination. Only verbal comprehension of the SOM-group was found to be slightly improved in the course of a six month period. No differences in general cognitive functioning and in behaviour were found between both groups.

Child Behavior↗
PubMed1989

[Clinical study of surgically treated parotid tumors during 1981-1985].

There is a great histologic diversity in parotid tumors. Four categories can be distinguished: pleomorphic adenoma, monomorphic adenomas, low-grade malignant tumors and high-grade malignant tumors. The most current neoplasm is the pleomorphic adenoma. The first three groups have a nearly similar clinical evolution and surgical treatment. The high-grade malignant tumors often cause a facial nerve paralysis and require a radical approach.

Adenoma↗
PubMed1989

Ciliogenesis and coordinated ciliary beating in human nasal epithelial cells cultured in vitro.

Human nasal epithelial cells, dissociated from nasal polyps, lost all their cilia when cultured as monolayers on 0.2% collagen gels in Ham's F12-DME 1/1, supplemented with NU-serum 10%, choleratoxin (10 ng/ml), retinoic acid (10(7) M) and antibiotics. These deciliated epithelial cell sheaths were then placed in a suspension culture system, and epithelial aggregates and vesicles formed. After 1 week in suspension, cilia progressively reappeared. This in vitro ciliogenesis resulted in ultrastructurally normal cilia with an intercellularly coordinated beating pattern. These epithelial aggregates and vesicles maintained this differentiated ciliary morphology and function for more than 6 months.

Cells, Cultured↗
PubMed1989

Age effect in speech audiometry and in brainstem electric response audiometry.

A review of the files of 152 patients with normal hearing or slight hearing loss revealed in the older age group that (1) scores on the synthetic sentence identification task (SSI, S/N = 0 dB) have a tendency to drop in comparison with the discrimination scores for phonetically balanced words in silence (PB), and that (2) the wave V of the auditory brainstem response shows a greater latency prolongation when the stimulation rate is increased. However, no statistical correlation between these two age-linked phenomena emerged, so they seem to be the result of two independent processes.

Adult↗
PubMed1988

Hypopharyngeal stenosis and fistulas. Use of the radial forearm flap.

The radial forearm flap is a thin, pliable, and well-vascularized fasciocutaneous flap. The forearm flap is, in selected cases, along with the pediculated regional and distant musculocutaneous flaps, a versatile method for pharyngeal reconstruction. We describe the use of the flap in nine clinical cases of hypopharyngeal stenosis and fistulas. The advantages of this method for hypopharyngeal reconstruction are presented.

Adult↗
PubMed1988

Vascularised fasciocutaneous flap for reconstruction of the hypopharynx.

The hypopharyngeal mucosa is a thin, pliable lining, which often needs replacement after tumor excision, stenosis and fistulae. The pectoralis major flap (Ariyan and Krizek, 1977) has brought an element of safety and reliability to one-stage pharyngeal reconstruction. The major disadvantage of these flaps is their bulk (2). The vascularised fasciocutaneous flap (especially the radial forearm flap) is a good alternative to be used in pharyngeal repair.

Adult↗
PubMed1984

The possible effects of conductive hearing loss on language development.

Recently some attention has been paid to the possibility that chronic serous otitis could adversely affect language development. Up to ten or fifteen years ago the hearing loss resulting from the disease was considered neglectable. In this contribution some arguments will be given as to prove that the latter might not always be true. Follows a review of some recent studies suggesting a causal relationship between secretory otitis and language development and scholastic learning. The need for further (longitudinal) research is emphasised.

Child↗
PubMed1984

Hearing in children.

The hearing tests for neonates, babies and young children must be adapted to the age of the patient. Neonates and young babies (under 9 months of age) are best examined with non-conditioned reflexes. For young children operant conditioning is the most suited technique. Preventive medicine is very much interested in hearing screening. We insist on a thorough history taking of the parents and on the importance of the high risk register for the early detection of congenital sensorineural hearing loss. We suspect that tympanometric screening of otitis serosa still is in an experimental stage.

Acoustic Stimulation↗
PubMed1976

[Rhinoscleroma in an immigrant].

A patient with rhinoscleroma was treated in our department. As far as we know it is the first importcase published in Belgium. Rhinoscleroma is an infectious disease caused by the Klebsiella Rhinoscleromatising. It is a chronic granulomatous process with subsequent stenosis and scarring. The nose and larynx are the most frequent localisations. The therapy consists of antibiotics in an early stage and is only palliative in the latter ones.

Diagnosis, Differential↗