Biomedical subjects

J Ulfarsson

Publications and source records attributed to J Ulfarsson.

3 recordsLinked to original sources

PubMed1994

Preventing falls and fractures.

One of four persons over age 65 in the community falls; those over age 75 in institutions fall more frequently. Falls, a complex phenomena suggesting present disease and predicting future disability, are caused by interactions between the environment and dynamic balance which is determined by the quality of sensory input, central processing, and motor responses. Clinical factors which predispose to falling often produce observable disturbances in gait and balance, making observation critical in assessment. Acute illness and drug therapy produce particularly preventable falls. Therapeutic exercise and environmental modification for safety are the clinical interventions most likely to successfully prevent fall-related injury.

Accidental Falls↗

PubMed1982

Selective serum IgA deficiency in Icelanders. Frequency, family studies and Ig levels.

More than 15,000 Icelanders (6.1% of the population), mostly healthy male blood donors, were screened in 1974-79 for selective IgA deficiency (SIgAD) by immunodiffusion (Ouchterlony). The frequency of SIgAD among blood donors was 1/633 (0.158%). Population and family screening yielded 35 individuals classified as IgA-deficient. Immunoglobulins A, G, M and E were measured in 119 family members of 18 propositi found by screening. Pedigree studies suggested both autosomal dominant and recessive modes of inheritance of SIgAD. A trend toward clustering of similar IgG and IgE levels (within the normal ranges) was apparent in several families. An increased IgG level in family members with SIgAD was significantly more frequent (p less than 0.001) than in members with normal levels of IgA. IgG levels were high in 12 (44%) and normal in 15 of 27 subjects with low or deficient IgA levels who were all healthy when examined, and only 5 gave a history of allergy or recurrent respiratory infections. It is suggested that immune response genes may cause the difference in Ig levels among the SIgAD family members.

Adult↗

PubMed1977

Studies on the Pelger anomaly in Iceland.

An Icelandic family, containing 15 members with Pelger anomally, is reported. Affected individuals in two branches of the family, living in the south-east and east of Iceland, have been traced to common ancestors born 200 years age. The results of scanning of blood films from approximately 20% of the population of Iceland suggest that the Pelger family described contains the only mutation of this kind in Icelanders.

Female↗