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Biomedical subjects

J Urbánková

Publications and source records attributed to J Urbánková.

At least 19 recordsLinked to original sources

[Basic epidemiologic indicators of venous diseases].

Venous diseases are among the major causes of morbidity and mortality in The Czech Republic. The incidence of venous diseases increases rapidly with age, especially in those older than 65 years. Among discussed entities is the most important deep venous thrombosis and its complications--pulmonary embolism and postthrombotic syndrome. We discuss epidemiology of acute and chronic venous diseases in context of risk factors and offer a short outline of currently applied therapy. Then we focus on the new perspective possibilities of treatment of venous diseases especially in acute states (including local thrombolysis), on its influence of quality of life, on the progression of diseases into chronic states and on its socioeconomic consequences.

Aged↗

[Interventional therapy of the inferior vena cava syndrome].

Interventional procedures are becoming increasingly popular in the treatment of impaired patency of deep venous system caused most often by extensive phlebothrombosis. Restoration of patency to affected venous segments while preserving the valvular function with a high degree of success in a relatively short period of time can be achieved by combination of endovascular methods such as catheter guided thrombolysis followed by percutaneous transluminal angioplasty and stenting. This approach enables not only the resolution of acute vascular complications but also the prevention of postthrombotic syndrome. This case report of a 52-year-old man with retroperitoneal fibrosis causing chronic compression of vena cava inferior further complicated by travelling associated bilateral ileofemoral thrombosis clearly demonstrates the wide ranging applications of the endovascular techniques.

Angioplasty, Balloon↗

[Prevention of viral hepatitis B transmission in the transplantation program].

The authors discuss possible detection of HBsAg with regards to demands of the transplantation programme. They compared the sensitivity of HBsAg detection by ELISA on kits of various firms, using a panel of sera previously examined by the RIA technique. The most sensitive and most rapid answer on the presence of a surface antigen of the hepatitis B virus by the ELISA technique can be obtained using a Wellozyme kit of Wellcome Diagnostics Co., i.e. within 60 minutes. The firm must, however, equip the kits with double volumes of positive and negative controls.

Enzyme-Linked Immunosorbent Assay↗

[Detection of antibodies and assessment of an international unit of anti-HBs specific immunoglobulin, HEPAGA].

The authors submit information on the presence and titre of antibodies against antigens of the hepatitis B virus [HB] and the Czechoslovak specific anti-HBs immunoglobulin, HEPAGA, and on the presence of the delta-antibody. The presence of the antibody against the surface antigen of the HB virus [HBsAb, anti-HBs] was examined in 32 batches, the antibody against the nucleus of the HB virus [HBcAb] and e-antigen [HBeAb] in a total of 27 batches. HBsAb was positive in the majority of cases still when diluted 1/2,500,000; HBcAb when diluted in the range from 1/25,000 to 1/2,500,000; the positivity of HBcAb ended with the exception of one batch at the dilution of 1/250. The delta antibody was detected only in batches from 1982 and 1983, in a maximum dilution of 1/8. All examinations were made by the radioimmunoassay [RIA] technique. The authors give also an account of the assessment of the international HEPAGA [IU/ml]. The last batch has 170 IU/ml.

Hepatitis Antibodies↗