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Biomedical subjects

J V Diengdoh

Publications and source records attributed to J V Diengdoh.

At least 19 recordsLinked to original sources
PubMed1993

Oncocytic variant of choroid plexus papilloma. Evolution from benign to malignant "oncocytoma".

BACKGROUND: The case of a left temporoparietal choroid plexus papilloma in a 12-year-old girl, which recurred 12 months after subtotal resection and apparent full recovery, is described. METHODS: The two consecutive surgical specimens were studied by light and electron microscopy. RESULTS: The first surgical specimen showed a tumor composed of cells with distended cytoplasm packed with numerous mitochondria characteristic of "oncocytic" change. Thus, tumor was the rare benign oncocytic variant of choroid plexus papilloma. A repeat histologic study of the recurrent tumor 12 months later showed evidence of malignant evolution in the form of multinucleated cells with frequent, often bizarre, mitotic figures. CONCLUSION: A rarely described oncocytic variant of choroid plexus papilloma that showed evidence of evolution from benign to malignant "oncocytoma" is discussed.

Adenoma↗
PubMed1990

Verrucous carcinoma of the base of the skull.

A case of verrucous carcinoma extensively destroying the base of the skull and involving the upper two cervical vertebrae is reported. Death resulted from cranio-cervical dislocation. Verrucous carcinoma, its aetiology and the relationship to the underlying chronic inflammatory process found in this case, are discussed.

Carcinoma, Papillary↗
PubMed1984

Hidradenoma with intracranial involvement.

A case of recurrent hidradenoma of the external ear with intracranial spread is described. The presentation, classification and management of this rare tumour are discussed and the importance of adequate long term review is stressed.

Adenoma, Sweat Gland↗
PubMed1984

Autosomal recessive late onset multisystem disorder with cerebellar cortical atrophy at necropsy: report of a family.

A sister and brother developed a progressive syndrome comprising bulbar palsy, supranuclear ophthalmoplegia, facial impassivity, and cerebellar ataxia together with a mixed pyramidal and extrapyramidal deficit in the limbs, in the fourth decade of life. Their parents were unaffected and inheritance was probably autosomal recessive. The female patient, who presented initially with bulbar and extrapyramidal dysfunction, was found to have cerebellar cortical atrophy at necropsy. The basal ganglia and brainstem were normal.

Adult↗
PubMed1983

Electron-microscopical study of a Rathke's cleft cyst.

The electron-microscopical appearance of a Rathke's cleft cyst is described. The cyst lining is seen to consist predominantly of secretory columnar epithelium, both ciliated and non-ciliated. There are also epidermoid cells occurring singly or in squamae. The histogenesis of Rathke's cleft cysts, in relation to craniopharyngiomas, is discussed.

Adolescent↗
PubMed1983

An intracranial metastasis from a PRL secreting pituitary tumour.

A 70-year-old man developed panhypopituitarism and was found to have hyperprolactinaemia and a locally invasive pituitary tumour. The visual fields were unaffected and therefore the patient was treated with hormone replacement only. After 3.5 years during which time the pituitary tumour had not enlarged further, the patient developed a mass in the left cerebello-pontine angle. This mass was subsequently shown to be entirely separate from, but histologically identical to, the pituitary tumour and the cells of both contained PRL. Evidence was obtained to show that the tumour had spread by a vascular route. This is the second reported case of a malignant prolactinoma.

Adenoma, Chromophobe↗
PubMed1981

Stimulus-sensitive spinal myoclonus.

Two cases of spinal myoclonus are described; in both patients myoclonus was responsive to stimuli and absent during sleep. The first patient was considered to have viral neuronitis and the condition resolved spontaneously. The second patient had spinal cord ischaemia; there was electro-physiological evidence of abnormal alpha motor neurone activity and histological study of the spinal cord revealed a severe reduction in small and intermediate neurones. This supports the theory that spinal myoclonus may result from abnormal activity of alpha motor neurones released from control by spinal internuncial neurones.

Adult↗
PubMed1976

Postirradiation necrosis of the temporal lobe presenting as a glioma. Case report.

A patient is reported who presented with manifestations of a space-occupying lesion in the left temporal lobe thought to be a metastasis, but on radiological examination and surgical exploration appeared to be a diffuse infiltrative glioma. Some 21 months earlier he had received a course of fast neutron therapy to a carcinoma of the left parotid gland. Diagnosis by microscopic examination revealed changes characteristic of delayed radiation necrosis.

Adenocarcinoma↗
PubMedDate not supplied

Aspergillosis of the nervous system. Report of two cases.

Two cases of Aspergillus infection of the nervous system are reported. In the first case it occurred in a healthy individual and presented as a space occupying lesion mimicking a tuberculous granuloma. In the second case it was an opportunistic infection in a patient with predisposing conditions and manifested as chronic meningitis with fatal arteritis.

Adult↗
PubMedDate not supplied

Intracranial malignant teratoma.

A case of malignant teratoma arising near the third ventricle in an adult is reported. It represented a true teratoma containing elements of all three germ layers of which two, namely the mesenchymal and endodermal elements have undergone malignant change. It was characterized by rapid recurrences after two operations with death occurring shortly after the second operation.

Adult↗