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J V FREI

Publications and source records attributed to J V FREI.

8 recordsLinked to original sources
PubMed1963

Mitoses: distribution in mouse ear epidermis.

Epidermal cell mitoses occur in a random spatial (Poisson) distribution in the plane of the epidermis of the mouse. It is therefore unlikely that the focal accumulation of a local extracellular factor is responsible for the initiation of mitoses.

Animals↗
PubMed1962

The fine structure of the basement membrane in epidermal tumors.

Epidermal tumors were induced in Swiss female mice by a topical application of 9,10-dimethyl-1,2-benzanthracene solution followed by repeated applications of croton oil solutions. Fourteen benign and malignant tumors were sampled 25 weeks after the treatment had begun, fixed in osmium tetroxide or potassium permanganate, and embedded in Epon. Sections stained with lead hydroxide were examined. In three tumors defects of the epidermal basement membrane were seen. These defects accompanied local invasion of the tumors. The possible mechanisms of the development of this unusual anatomical situation are discussed.

9,10-Dimethyl-1,2-benzanthracene↗