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Biomedical subjects

J V Jestico

Publications and source records attributed to J V Jestico.

7 recordsLinked to original sources
PubMed1999

The Redbridge Stroke Unit--experience gained from a one year study.

OBJECTIVE: To assess the impact of stroke unit on overall management of stroke illness within the district. SETTING: A multidisciplinary stroke unit. METHODS: Study was made of the mortality, durations of stay and discharge destinations of 76 patients with stroke selected for stroke unit rehabilitation from a total of 164 stroke patients admitted to the Redbridge Hospitals during a 12 month period. These were compared with the outcomes of stroke patients admitted during the year prior to the Unit opening. RESULTS: There was no difference in mortality, 16% in each group. The durations of admissions of patients treated in the Stroke Unit were longer than the control group, although there was no increase in the mean duration of hospital stay of the total number of stroke patients. When patients treated in the stroke unit were compared with a selected control group taken from the stroke patients admitted during the previous year, 27% more patients were discharged back into the community, 4% less patients required long stay elderly care and 20% less patients required further rehabilitation outside the district. When all stroke admissions were considered, 29% more patients were discharged home, 10% less patients required long stay care and 15% less patients required further specialized rehabilitation. CONCLUSION: Treatment in the stroke unit substantially improved patient outcome.

Adult↗
PubMed1985

An hereditary sensory and autonomic neuropathy transmitted as an X-linked recessive trait.

Five members of a single family presented with neuropathic deformities and ulceration of the feet developing in the first and second decades of life, and progressed slowly over many years. In this form of hereditary sensory and autonomic neuropathy, there was minimal tendon reflex impairment, cutaneous sensory impairment was restricted to the feet, and there was no autonomic dysfunction. The only neurophysiological abnormality was that of reduced or absent sural nerve sensory action potentials. Sural nerve biopsies taken from two affected family members showed changes of a chronic neuropathy with loss of myelinated fibres, particularly affecting those of small diameter. Unmyelinated fibres were present in normal numbers. This condition differed from other forms of hereditary sensory and autonomic neuropathy having an X-linked recessive mode of inheritance.

Adolescent↗
PubMed1984

Whole blood cyanide levels in patients with tobacco amblyopia.

Three patients presented with painless bilateral visual failure due to tobacco amblyopia. The whole blood cyanide levels were raised above those predicted from their high tobacco consumption, approaching lethal levels reported from acute inhalation of cyanide. Each patient had an excessive alcohol intake with biochemical evidence of hepatic dysfunction, the elevated whole blood cyanide levels being attributed to the associated impairment of cyanide detoxification. In each case the improvement in visual acuities following abstinence and hydroxycobalamin therapy was accompanied by a reduction in the whole blood cyanide level to within the normal range. Serial measurements of whole blood cyanide, serum alcohol, and the detection of urinary nicotine provided valuable indices of the patient's subsequent compliance and clinical progress.

Adult↗
PubMed1983

Central cord lesions in cervical spondylotic myelopathy.

Two patients with cervical spondylotic myelopathy presented with features suggesting syringomyelia. One patient had a Charcot joint of the wrist, and both had dissociated sensory loss in the upper limbs. The possible vascular basis of these central cord lesions is discussed.

Aged↗
PubMed1976

Changes in nystagmus on raising body temperature in clinically suspected and proved multiple sclerosis.

Electronystagmography was used to record the appearance or alteration of nystagmus after raising the body temperature by a heat cradle. Nystagmus was increased or provoked in 13 out of 15 patients with clinically proved multiple sclerosis, in eight out of 12 suspected cases, but in no normal controls. No positive results were obtained in 12 patients with other neurological diseases, even when nystagmus was part of the clinical picutre. The technique is simple to use and may have a role in the diagnosis of multiple sclerosis.

Adult↗
PubMed1976

Malignant meningioma with liver metastases and hypoglycaemia. A case report.

The history, clinical course and pathological findings are reported of a patient who developed a recurring, malignant meningioma. Widespread extracranial metastases occurred, particularly in the liver. Hypoglycaemia was a prominent feature during the late course of the disease. The influence of the histological type of meningioma and the effects of surgical interventions on the development of extracranial metastases are discussed together with the relationship of the tumour to hypoglycaemia.

Central Nervous System Diseases↗