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Biomedical subjects

J V Mauro

Publications and source records attributed to J V Mauro.

5 recordsLinked to original sources

Olfactory neuroblastoma: report of case.

A case of olfactory neuroblastoma has been presented. The clinical signs and symptoms described in this case are not uncommon and often result in early misdiagnosis. The favorable prognosis for olfactory neuroblastoma dictates early diagnosis, using the clinical signs and symptoms along with adjunctive aids such as incisional biopsy, panoramic survey, and CT scanning. Surgical excision followed by radiation therapy in an early diagnosed case of olfactory neuroblastoma greatly increases the five-year survival rate.

Aged↗

Hereditary angioneurotic edema: clinical management and case report.

Hereditary angioneurotic edema, although a rare clinical entity, can be fatal if diagnosis and appropriate therapy are not instituted before the performance of routine dental and oral surgical procedures. The pathophysiology, physical findings, and therapeutic treatment modalities have been reviewed, and a case involving both restorative and surgical dental intervention has been presented.

Adult↗

Prolonged succinylcholine-induced apnea caused by atypical cholinesterase: report of case.

A case of prolonged apnea after administration of succinylcholine in a patient homozygous for the dibucain variant cholinesterase (genotype E1aE1a) has been presented. Knowledge of the patient's medical history, preoperative laboratory tests, and the length of apnea enabled the surgical team to eliminate liver disease, carcinoma, and malnutrition from the differential diagnosis. This, in addition to the patient's failure to respond to an anticholinesterase agent, led to the belief that the patient had an atypical cholinesterase response to succinylcholine and not one secondary to a decreased production of cholinesterase enzyme from an impaired liver or prolonged paralysis for the nondepolarizing agent, pancuronium. Treatment consisted of maintaining adequate pulmonary ventilation nitrous oxide sedation to diminish anxiety until the patient regained spontaneous respiration. Anticholinesterase agents were used after the patient had progressed to a phase II depolarization block. After a cholinesterase assay of the family's serum, all members having the atypical allele were instructed to obtain medical alert identification.

Adult↗