Prostaglandin E1 for treatment of elevated pulmonary vascular resistance in patients undergoing cardiac transplantation.
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Alprostadil↗
Biomedical subjects
J V Park
Publications and source records attributed to J V Park.
Cardiopulmonary bypass and myocardial protection: management problems in cardiac surgical patients with cold autoimmune disease.
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Anemia, Hemolytic, Autoimmune↗
TRNA2Gln Su+2 mutants that increase amber suppression.
We selected mutants of lambda pSu+2 which had an increased ability to suppress on Escherichia coli trp B9601 amber mutation on translationally stringent rpsL594 streptomycin-resistant ribosomes. tRNA2Gin Su+2 molecules produced from eight independent mutants were purified, and their ribonucleic acid sequences were determined. Two types of mutations were mapped to the tRNA2Gin Su+2(glnV) gene by this method. Both altered the pseudouridine at position 37 of the tRNA anticodon loop. Seven of the isolates were transitions (pseudouridine to cytosine), and one was a transversion (pseudouridine to adenine). These mutations resulted in Su+ transfer ribonucleic acid molecules that exhibited higher transmission coefficients than their parent Su+2 transfer ribonucleic acids. As judged by their suppressor spectra on T4 amber mutants, which were almost identical to that of Su+2, the two mutant Su+ transfer ribonucleic acids inserted glutamine at amber sites.
Amino Acyl-tRNA Synthetases↗