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Biomedical subjects

J Valenzuela

Publications and source records attributed to J Valenzuela.

At least 19 recordsLinked to original sources

[Clinical characteristics of patients with multiple or giant peptic ulcers].

The incidence and clinical characteristics of multiple or giant ulcers (over 20 mm for duodenal ulcer or 25 mm for gastric ulcer) was evaluated among 1434 patients with peptic ulcers. For gastric ulcers, multiple and giant lesions were found in 27% and 14% of patients respectively. Among duodenal ulcers the corresponding figure were 16% and 2.4%. Patients with triple gastric ulcers have a greater incidence of massive bleeding. Patients with triple duodenal ulcers are older, have more massive bleeding and have a greater incidence of gastric retention and hypersecretion when compared to patients with single or double duodenal ulcers. Giant gastric ulcer was associated to a shorter history and more massive bleeding; giant duodenal ulcer was associated to older age, more massive bleeding and gastric retention, when compared to patients with common size ulcers.

Adult

[Aseptic meningitis following spinal anesthesia. Report of a case].

Aseptic meningitis after lumbar puncture and spinal anesthesia is a rare but serious complication, whose acute onset and clinical symptoms mimic septic meningitis. A 33 year old woman presented this complication 5 h after an uneventful cesarean section under subarachnoid blockade. Though lumbar puncture revealed pleocytosis with negative Gram stains and cultures, she was treated with antibiotics and made a full recovery. The clinical picture, differential diagnosis and value of early lumbar puncture are discussed. The successful use of midazolam to treat psychomotor agitation in this patient is also reported.

Adult

[Prevalence of esophageal and gastrointestinal symptoms in Chilean adults].

We surveyed 300 randomly selected presumable healthy adults for previously defined gastrointestinal and esophageal symptoms. Heartburn was the most common symptom, more frequent in females than in males (p less than 0.01). An association of esophageal symptoms to heartburn but not to smoking habit was found. Constipation was frequent in females and diarrhea in males. We conclude that esophageal symptoms are frequent in presumable healthy individuals.

Adult

[Scintigraphic method for the study of painful shoulder syndrome: differential count].

Pain may be present in different sites in patients with a painful shoulder syndrome. We compared (scintigraphy) 56 patients with unilateral painful shoulder syndrome and 26 controls. A differential count index (DCI) was used to evaluate painful sites. Values (mean +/- SD) obtained for patients and controls at different sites were: acromioclavicular joint 1.53 +/- 0.33 vs 1.09 +/- 0.08 (p less than 0.005); * 1.30 +/- 0.39 vs 1.07 +/- 0.07 (p less than 0.01); scapular insertion of deltoid muscle 1.61 +/- 0.40 vs 1.10 +/- 0.10 (p less than 0.005); scapular insertion of trapezius muscle 1.31 +/- 0.21 vs 1.08 +/- 0.06 (p less than 0.005). Average number of painful sites for patients 40 years and older was 2.24 vs 1.58 for younger patients (p less than 0.005). Sensitivity and specificity for pain in the various sites was: * 50% and 90%: acromioclavicular joint 85% and 88%; scapular insertion of deltoid muscle 83 and 90%; and scapular insertion of trapezius muscle 71 and 80%, respectively.

Adult

[Unusual sarcomas of the breast. Report of 3 cases].

Non phylloides sarcomas of the breast are infrequent malignant tumors that can be identified only at histologic examination since clinical presentation may not differ from the more frequent phylloides type. In addition to fibrosarcoma, leiomyosarcoma, rhabdomyosarcoma, angiosarcoma and liposarcoma, the stromal sarcoma of the breast has been recently identified. We report 3 such cases with heterologous components of osteosarcoma, chondrosarcoma and liposarcoma. A third case with an anti-sarcoma appearing post radiotherapy for breast carcinoma is also reported.

Adult

Epidemiology of strongyles in ponies in Ontario.

The transmission of strongyles among 54 Shetland-cross mature ponies was examined from May 30 to November 22, 1983 when the ponies were on pasture and over the ensuing winter when they were in loose housing. Fecal and pasture herbage samples were taken fortnightly through the pasture season and periodically thereafter. Three foals born and reared on pasture were weaned and removed from pasture, two in early August and one in mid-September, and housed for a period before necropsy. Daily maximum and minimum air temperature and total precipitation were recorded. The mean fecal strongyle egg count was highest in the spring and early summer and lowest over the winter. Few larvae were found on the herbage in late May and their numbers were near zero by the third week in June. Subsequently, the numbers increased, were highest from late August through to mid-October and then declined and were low over the winter. Few strongyles were found in two foals removed earlier in the season, and many in the one later. The transmission of strongyles appeared to occur, therefore, principally from mid-summer to mid-fall.

Animals

Recurrent ulcer after successful treatment with cimetidine or antacid.

This study was designed to compare the rates of duodenal ulcer healing and recurrence after treatment with cimetidine or antacid. Patients with endoscopically documented duodenal ulcer received cimetidine, 1200 mg daily, or Mylanta II, 7 oz daily, in a randomized, double-blind trial. For the 69 patients in each group who completed the healing phase of the trial, endoscopic ulcer healing was almost identical. At 2, 4, and 6 wk, the cumulative percent healed on antacid was 33%, 64%, and 80%, and on cimetidine it was 25%, 62%, and 86%. The 114 patients with healed ulcer were observed on no therapy and underwent additional endoscopy to detect recurrences when symptomatic or at 3, 6, and 12 mo. There was no difference in the frequency of recurrences between treatments. At 3 and 6 mo, the cumulative percentages of patients with recurrence were 29% and 56% after antacid therapy and 36% and 55% after cimetidine therapy. Some patient variables were associated with delayed ulcer healing or ulcer recurrence. These included sex, pain frequency, smoking, disease duration, and acid secretion.

Aluminum Hydroxide