PubMed Health⌕ Search

Biomedical subjects

J Van Goethem

Publications and source records attributed to J Van Goethem.

11 recordsLinked to original sources
PubMed2004

Does the location of a vascular loop in the cerebellopontine angle explain pulsatile and non-pulsatile tinnitus?

The purpose was to investigate patients with unexplained pulsatile and non-pulsatile tinnitus by means of MR imaging of the cerebellopontine angle (CPA) and to correlate the clinical subtype of tinnitus with the location of a blood vessel (in the internal auditory canal or at the cisternal part of the VIIIth cranial nerve). Clinical presentation of tinnitus and perceptive hearing loss were correlated. In 47 patients with unexplained tinnitus, an MR examination of the CPA was performed. Virtual endoscopy reconstructions were obtained using a 3D axial thin-section high-resolution heavily T2-weighted gradient echo constructive interference in steady state (CISS) data-set. High-resolution T2-weighted CISS images showed a significantly higher number of vascular loops in the internal auditory canal in patients with arterial pulsatile tinnitus compared to patients with non-pulsatile tinnitus (P<0.00001). Virtual endoscopy images were used to investigate vascular contacts at the cisternal part of the VIIIth cranial nerve in patients with low pitch and high pitch non-pulsatile tinnitus. A significantly different distribution of the vascular contacts (P=0.0320) was found. Furthermore, a correlation between the clinical presentation of non-pulsatile tinnitus (high pitch and low pitch) and the perceptive hearing loss was found (P=0.0235). High-resolution heavily T2-weighted CISS images and virtual endoscopy of the CPA can be used to evaluate whether a vascular contact is present in the internal auditory canal or at the cisternal part of the VIIIth cranial nerve and whether the location of the vascular contact correlates with the clinical subtype of tinnitus. Our findings suggest that there is a tonotopical structure of the cisternal part of the VIIIth cranial nerve. A correlation between the clinical presentation of tinnitus and hearing loss was found.

Adolescent↗
PubMed2000

Maxillo-facial trauma.

Injuries to the facial bones, orbits and adjacent soft tissue structures are common. Despite the increasing safety precautions in modern cars, facial injury is very often caused by motor vehicle accidents. Severe trauma to the face is a strong indication for radiological investigation. In the patient with maxillo-facial trauma, the radiological exploration of should answer two major questions: do the fractures involve areas that may alter the physiologic function of the sinuses, mouth, nasal vault or orbit?, and will the fracture result in any cosmetically detectable abnormality? The goal of the radiological work-up is to define the number and exact location of the fractures, to determine if there is any depression, elevation, or distraction of the fracture fragments, and to assess concomitant soft tissue complications. In this article, we review the role of clinical evaluation, plain X-rays, computed tomography (CT) and magnetic resonance imaging (MRI). Imaging findings are correlated with anatomic and physiopathologic considerations. We present a practical classification system of facial trauma, with emphasis on trauma of the paranasal sinuses and facial bones (nasal and tripod fractures, Le Fort fractures) and orbits (foreign bodies, soft tissue and orbital wall injuries such as blow-in and blow-out-, lateral wall- and apical fractures). A third part focuses on trauma of the mandible and the temporomandibular joints.

Diagnostic Imaging↗
PubMed1998

Histopathologic comparison of a pulmonary autograft and pulmonary homograft in a patient 17 months after a Ross procedure: an autopsy study.

BACKGROUND AND AIM OF THE STUDY: The Ross operation has become very popular during the last decade. However little is known about the cellular behaviour of a normally functioning pulmonary autograft. METHODS: This case report deals with a 14-year-old female who died from a non-valve-related cause 17 months after a Ross-Konno operation using a cryop-reserved viable pulmonary homograft for the right outflow tract. Comparison is made between the homologous and autologous pulmonary valves by macroscopic description, histology and immunohistochemistry. RESULTS: The autograft kept its cellular population-except for the dendritic cells which have disappeared, and developed a jet lesion on the ventricular aspect of one cusp as a likely adaptation to a transvalvular gradient. The homograft was extensively devitalized, its cusps being partially covered with a fibrous sheath of recipient origin; few inflammatory cells, consisting of macrophages and rare T lymphocytes were present. CONCLUSIONS: The most puzzling observation, which needs confirmation, is the selective disappearance of the dendritic cells from the viable autograft. It is disappointing that a viable cryopreserved homograft valve has devitalized in the midterm. This phenomenon seems to result from a clinically silent immune reactions.

Adolescent↗
PubMed1997

Magnetic resonance imaging of localized giant cell tumour of the tendon sheath (MRI of localized GCTTS).

The objective of this study was to evaluate the appearance of localized giant cell tumour of the tendon sheath (GCTTS) on unenhanced and Gd-enhanced MR images. MR images of 13 histologically proven cases of localized GCTTS were evaluated for mean size, location, homogeneity and signal intensity (SI) on both T1- and T2-weighted images, and enhancement pattern. All lesions except 1 affected young adults. On T1- and T2-weighted images, lesions showed predominantly low SI equal to or slightly higher than skeletal muscle. On Gd-enhanced T1-weighted images, strong homogeneous enhancement was seen. These findings reflect the underlying histological composition of the lesion; haemosiderin deposition in xanthoma cells, shortening T2-relaxation time, and abundant collagenous proliferation are responsible for low SI on T1- and T2-weighted images. Strong homogeneous enhancement originates from numerous proliferative capillaries in the collagenous stroma. We conclude that these characteristic MR features, together with clinical information, are a valuable diagnostic tool in offering a correct preoperative diagnosis.

Adolescent↗
PubMed1996

Tuberculous meningitis in immunocompetent adults: two cases with a clinico-radiological discussion.

In developed countries with a low incidence of tuberculosis, infection with Mycobacterium tuberculosis is easily overlooked as the cause of meningitis in an immunocompetent adult. Two cases are presented, with emphasis on the main reasons for delay of diagnosis. Neuroradiology revealed a progressive hypertrophic basal meningitis. The clinical and radiological outcome was good after tuberculostatic and corticosteroid treatment.

Adult↗
PubMed1993

Tuberous sclerosis: CT and MRI characteristics.

Tuberous sclerosis is a disease characterized by the presence of hamartomatous nodules in various organs, including the brain. Thirteen CT scans and four MR investigations were performed in 13 patients. CT is superior to MR in demonstrating the presence of subependymal nodules, thereby confirming or establishing the diagnosis of tuberous sclerosis. MR is superior to CT in demonstrating the peripheral lesions, which are characterized by a long T2-relaxation time. Differentiation between cortical tubers and subcortical lesions is not yet accurate.

Adolescent↗