Biomedical subjects

J Veen

Publications and source records attributed to J Veen.

11 recordsLinked to original sources

PubMed1992

Microepidemics of tuberculosis: the stone-in-the-pond principle.

In a low prevalence country with no systematic BCG vaccination and a low frequency of environmental mycobacterial infections, for each recognized case of tuberculosis or infection with M. tuberculosis source detection should be undertaken. Sometimes this search will lead to discovery of a microepidemic. The extent of contact screening in a microepidemic can easily be determined if observed group prevalences are compared to expected group prevalences. The described method illustrates this search for contacts in concentric circles around the source case: the stone-in-the-pond principle.

Adolescent↗

PubMed1991

[Tuberculosis in alpacas; a zoonosis as an imported disease].

In the Netherlands, in 1988, a micro-epidemic of tuberculosis in alpacas recently imported from Peru prompted health authorities to initiate investigation of human and animal contacts. Although the animal trainer and his assistant suffered from pulmonary tuberculosis, they turned out to be infected by Mycobacterium tuberculosis, while the animals later proved to be infected by M. bovis. The alpacas' caretaker and a laboratory technician present at the autopsy, were probably infected by animal contact. Elsewhere in the country, three more alpacas were reported with tuberculosis at the time; this initiated a large-scale investigation among alpacas, llamas etc., but no further cases were detected. The possibility of imported zoonoses, especially after 1992, is discussed.

Adult↗

PubMed1991

[Tuberculosis in imported alpacas--a zoonosis--now what?].

An outbreak of tuberculosis caused by M. bovis in imported Alpaca's in the Netherlands is reported. A review of the outbreak of the disease is followed by a more detailed discussion of the symptoms, diagnostic testing with the tuberculin skin test and the ELISA test, the gross lesions, the bacteriological examinations, the control measures and the legal aspects. As tuberculosis is not referred to in the Live-Stock Act, the control measures had to be based on the humane Control of Infectious Disease and Tracing the Causes of Disease Act. In the discussion, it is advocated to pay attention to more species of animals than only to the traditional live-stock in the proposed Health and Welfare of Animals Act.

Animals↗

PubMed1991

Tuberculosis in a low prevalence country: A wolf in sheep's clothing.

In low prevalence countries group epidemics or "micro-epidemics" of tuberculosis behave as a point-prevalence epidemic. Contact tracing follows the "Stone-in-the-Pond Principle", persons belonging to the inner circle of a source of infection being examined first. Important factors contributing to the occurrence of a micro-epidemic are prolonged patient's and doctor's delay and the dark damp atmospheres of discotheques.

Adult↗

PubMed1989