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Biomedical subjects

J Veerkamp

Publications and source records attributed to J Veerkamp.

9 recordsLinked to original sources

Predicting dental anxiety. The clinical value of anxiety questionnaires: an explorative study.

AIM: This was to explore the usefulness of the Dental Subscale of the Children's Fear Survey Schedule (CFSS-DS) and the Child Behaviour Checklist (CBCL), used prior to treatment, in relation to the actual behaviour displayed during treatment. METHODS: The study group was 26 children, referred to a special dental care clinic for behaviour management problems, mostly caused by dental fear. Questionnaires used were the parent versions of the Dental Subscale of the Children's Fear Survey Schedule (CFSS-DS) and the Child Behaviour Checklist (CBCL). Behaviour was registered on videotape and scored by independent observers using the modified Venham scale. Treatment consisted of a familiarization visit and two restorative sessions. RESULTS: There was a significant reduction in fear, based on pre and post treatment CFSS-DS scores, and also the child's fearful behaviour during the two restorative sessions appeared to be related. But no correlation was found between the CFSS-DS and the CBCL, nor between the CFSS-DS and the behaviour displayed during the treatment sessions. CONCLUSION: The child's anxious behaviour during actual restorative dental treatment is not so much related to its own anticipatory dental anxiety or the anxiety of the mother. Results support the role of a multifactorial model.

Behavior Therapy↗

Altered Ca2+ responses in muscles with combined mitochondrial and cytosolic creatine kinase deficiencies.

We have blocked creatine kinase (CK)-mediated phosphocreatine (PCr) -->/<-- ATP transphosphorylation in skeletal muscle by combining targeted mutations in the genes encoding mitochondrial and cytosolic CK in mice. Contrary to expectation, the PCr level was only marginally affected, but the compound was rendered metabolically inert. Mutant muscles in vivo showed significantly impaired tetanic force output, increased relaxation times, altered mitochondrial volume and location, and conspicuous tubular aggregates of sarcoplasmic reticulum membranes, as seen in myopathies with electrolyte disturbances. In depolarized myotubes cultured in vitro, CK absence influenced both the release and sequestration of Ca2+. Our data point to a direct link between the CK-PCr system and Ca2+-flux regulation during the excitation and relaxation phases of muscle contraction.

Adenosine Triphosphate↗

General method for analysing dentist-patient interaction.

The interaction between dentist and patient during dental treatment may influence the frequency of dental visits in the future because this interaction may increase the dental fear of the patient. To find the characteristics of the dentist's behavior that increase or decrease dental fear a statistical analysis of the interaction may be used. Data of such interactions are known as time series. Because it is highly probable that the behavior of an individual at two different points in time is autocorrelated a correct statistical analysis of the interaction between dentist and patient must take this possibility into account. A general statistical method is proposed that can take autocorrelations into account. The method is compared with a simpler method that may not deal adequately with autocorrelations.

Child↗

Amyloid in the horse: a report of nine cases.

Out of approximately 16,000 horses referred for clinical examination, nine had amyloidosis. Six of these horses had localised amyloid deposits in the wall of the nasal meatus and ventral turbinates associated with epistaxis. Horse 1 also developed malignant histiolymphocytic lymphosarcomas. The amyloid deposits were potassium permanganate-resistant and tryptophan-positive. Gel filtration of solubilised amyloid fibrils from Horse 1 revealed a major retarded fraction with an apparent molecular weight of 20 kD. This protein had an amino acid composition similar to human AL-amyloid proteins and horse immunoglobulin light chains. On Western blot a strong cross-reaction was observed between horse 1gG2a light chains and the Horse 1 amyloid. Horses 7 to 9 had suppurative verminous aneurysm, tuberculosis and an adrenal cortical adenoma, respectively, and had generalised amyloid deposits in liver and spleen. These amyloid deposits were found to be potassium permanganate-sensitive and positive for tryptophan. Gel filtration of solubilised amyloid fibrils from Horse 8 revealed a major retarded fraction (protein AA) with an apparent molecular weight of 10 kD. Immunoperoxidase-antiperoxidase staining showed the localised deposits to be negative or only weakly positive with antisera against bovine, hamster, dog and human protein AA and to be positive with anti-horse-one amyloid protein. The generalised deposits were found to be positive with the antisera against allogenic protein AA. The results of the potassium permanganate incubation, biochemistry, immunoblotting and immunochemistry, indicate that the localised amyloid of Horse 1 and most likely the amyloid of Horses 2 to 6, is of the AL-type. The generalised amyloid deposits were found to be of the AA type.

Amyloid↗

Interactions between dentists and anxious child patients: a behavioral analysis.

The aim of this investigation was to study the effect of dentists' behavior on the (anxious) behavior of child patients. Twelve high-anxious and a matched group of 12 low-anxious children from 6 to 12 yr of age were selected and randomly assigned to one of six dentists: three with experience in treating fearful children and three without such experience. Each child was treated twice. The first treatment was prophylactic, the second, 2 wks later, consisted of preparation and restoration of a cavity (Class 1) under local anesthesia. While both treatment sessions were videotaped, only the latter one was used in this study. Data analysis which did not control for autocorrelations revealed 22 (out of 28) significant effects. Data analysis with a control for autocorrelations showed only two significant effects: 'working contact', which decreased fear-related behavior and 'no physical contact', which increased fear-related behavior.

Anxiety↗

Behavior of dentists and child patients during treatment.

This study is part of a larger research project which aims to analyze children's dental fear by making a detailed analysis of the behavioral interactions between dentists and anxious child patients. The behavior of 12 high- and 12 low-anxious children was recorded on videotape during two dental visits in which the children were treated by either experienced or inexperienced dentists. Results indicated a relation between the dentist's experience in treating anxious children and the behavior of child patients. In general, children treated by experienced dentists showed more fear-related behaviors. Furthermore, the behavior of the dentist was related to both his experience and the fear level of the child patient. Experienced dentists showed more communicative behaviors than the inexperienced dentists, but all dentists communicated more with high- than with low-anxious children. Experienced dentists worked faster than inexperienced dentists, but treatment of the high-anxious children was not more time-consuming than treatment of the low-anxious children.

Anxiety↗

Dentists' behavior in response to child dental fear.

Dental fear is a multifactorial problem frequently encountered during dental treatment of children. Studies have indicated that, among others, the behavior of the dentist may play a part in the development of this dental fear. The present study was undertaken to examine the behavioral aspects of the dentist-patient relationship, and specific dentists' behavior that can reduce dental fear. The behavior of forty children referred to a center for special dental care and of two dentists was assessed during treatment. T-test results showed that the children's level of fear decreased after treatment (mean 3.2 vs. 2.1, t = -5.6, p = .000). In addition, it was found that the dentists behaved more directly and authoritatively during the treatment of highly fearful children than during the treatment of relatively less fearful children (p < or = .034). It seems that this direct approach had a positive, long-term effect on these children's fearful behavior during treatment.

Attitude of Health Personnel↗