WHO consensus statement.
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Biomedical subjects
Publications and source records attributed to J Vermeulen.
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Seventeen spontaneous speech measures and scores on a naming test, employed to characterize the expressive performance of 121 aphasics, were subjected to a factor analysis. Five factors were obtained: (1) Syntactic ability, (2) Phonological paraphasia, (3) Neologistic paraphasia, (4) Articulatory impairment, and (5) Vocabulary. Relationships of the factors to naming error types were examined in order to elucidate the nature of some of the factors. Also, the relationships of the expressive factors to auditory comprehension tests were explored, such an exploration being relevant to the issue of the overlap between expressive and receptive functions.
A 25 year-old man with Hodgkin's disease, presented a confusional state with choreatic movements, 1 hour after a lymphography. CT showed high density in the heads of both caudate nuclei, and in the cortex. The patient's state improved and he entirely recovered within 2 weeks, while CT returned to normal. No right-to-left shunt was demonstrated. The mechanisms of this infrequent complication of lymphography are discussed: exceeding filtration capacity of lung because of a too rapid administration of contrast or severe lung embolism? intracardiac right-to-left shunts? microscopic arteriovenous shunts in the lung? bad venous cerebral drainage consecutive to a vena cava superior syndrome?
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The concentration of steroid hormones in saliva is believed to reflect the concentration of free hormone in blood. Because the assay for progesterone in saliva has not been rigorously validated, we investigated some of the analytical variables involved. Saliva samples were divided into two portions. One was centrifuged and the supernate used for extraction; the other was homogenized by sonication and used as such for extraction. Progesterone concentrations in homogenized whole saliva were double or triple those in supernates. By equilibrium dialysis we established that 85% of progesterone was in the free form in supernates but only 60 to 70% in homogenized whole saliva, depending upon the phase of the cycle of the subjects. Salivary flow was stimulated by crystals of citric acid; unstimulated and stimulated saliva samples were obtained from the same person. Progesterone concentrations were significantly (p less than 0.02) higher in stimulated samples than in unstimulated ones, particularly in samples collected during the luteal phase.
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