PubMed Health⌕ Search

Biomedical subjects

J Viñuelas

Publications and source records attributed to J Viñuelas.

10 recordsLinked to original sources

Meningeal leishmaniosis induced by Leishmania infantum in naturally infected dogs.

We report two cases of meningitis caused by Leishmania infantum in naturally infected dogs. In both of these dogs the typical phenotypic features of granulomatous meningitis were observed with important lympho-plasma-cellular infiltrates and the presence of large numbers of parasites inside and outside macrophages. The immunological study of the cerebrospinal fluid of both animals showed that a large number of protein bands were recognized by those fluids and that they were similar to the ones recognized by the sera from the same animals. To our knowledge, this is the first description of meningitis associated to leishmaniosis.

Animals↗

[Atypical radiologic manifestations of Pneumocystis carinii pneumonia].

Pneumonia due to Pneumocystis carinii (PC) is characterized, in most cases, by the existence of infiltrates of interstitium or bilateral interstitium-alveolar type on the thorax radiography. However atypical radiological findings associated with this type of opportunistic infection are being described more and more frequently. We present two patients with Acquire Immune Deficiency Syndrome (AIDS) and pulmonary infection due to PC, with very unusual radiological findings. First patient showed multiple pulmonary cavitated nodules; the other a cavitated infiltrate in superior right lobule. Clinicians dealing with AIDS patients must be familiar with this unusual radiologic findings associated with PC in order to avoid diagnostic mistakes.

Adult↗

[Bacteremic pneumonia caused by Rhodococcus equi and HIV infection. Report of a new case and review of the literature].

Rhodococcus equi (Corynebacterium equi) is able to produce infections not only in animals but also in patients, usually immunosuppressed ones. We report a new case of bacteremic pneumonia in a drug addict who was also infected by HIV. X-ray film of the chest showed a cavitated infiltrate in right upper lobe. R. equi was recovered from blood, respiratory secretions and lung tissue. The patient was with a prolonged course of antibiotics and also surgical treatment. In spite of both therapies, the patient died. We believe that this infection has to be considered in HIV infected patients with cavitated pneumonia and that early surgical treatment, combined with a prolonged course of multiple antibiotics, is advisable. Finally, in view of the severity of this infection, and its relation with other opportunistic infections, we believe that could be included as AIDS diagnostic criteria.

Acquired Immunodeficiency Syndrome↗

[Bacteremia caused by Streptococcus pneumoniae and HIV infection].

We analyze seven patients with HIV infection that developed community-acquired bacteremic pneumonia due to Streptococcus pneumoniae. Six patients were drug addicts and one was a male homosexual. Five patients have been previously diagnosed of having AIDS. All patients had fever with respiratory tract symptoms and abnormal X-ray films of the chest, in five cases the lesions were located in both lungs. Only four patients showed a pattern of consolidation. The remaining cases showed an interstitial pattern. All but one patient have a CD4 lymphocyte count equal or less than 50 cells/mm3. Clinical evolution was good with antibiotic treatment. In two cases a relapse occur. No deaths were seen directly related to pneumococcal infection. We want to highlight the relative lack of severity of this infection and we suggest the use of antibiotic treatment for at least 14 days.

Acquired Immunodeficiency Syndrome↗

Flow cytometric quantitation of phagocytosis in heparinized complete blood with latex particles and Candida albicans.

We report a rapid method for the flow cytometric quantitation of phagocytosis in heparinized complete peripheral blood (HCPB), using commercially available phycoerythrin-conjugated latex particles of 1 micron diameter. The method is faster and shows greater reproducibility than Bjerknes' (1984) standard technique using propidium iodide-stained Candida albicans, conventionally applied to the leukocytic layer of peripheral blood but here modified for HCPB. We also report a modification of Bjerknes' Intracellular Killing Test to allow its application to HCPB.

Candida albicans↗