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Biomedical subjects

J Vierik

Publications and source records attributed to J Vierik.

At least 19 recordsLinked to original sources

[Lipid composition of the myometrium during labor].

Lipids represent one of the basic components of each cellular and subcellular membrane of the myometrium and their fluidity has a strong influence upon membrane function. Human myometrium was obtained at cesarean sections. Lipids were separated by one-dimensional thin layer chromatography. The chromatoplates were determined on the densitometer Shimadzu CS 930. Lipid profile of the myometrium was studied before the 37th week of pregnancy, at term without contractile activity, further during at term labor with normal contractile activity and at failure of myometrial contractility. Analysis of the obtained data showed changes in lipid fluidity, namely a decrease before the 37th week of pregnancy and at failure of myometrial contractions during at term labor. The decrease of fluidity was caused by a higher content of total cholesterol and a lower content of total phospholipids in the myometrium.

Female↗

[Incidence of macroscopic changes in the placenta in intrauterine growth retardation in neonates].

Advances in noninvasive imaging techniques allow to visualize the placenta and changes of its structure in the course of gestation. Macroscopic examination of the placenta in newborns with intrauterine growth retardation reveals changes responsible for reduced placental functions. These can then be diagnosed in utero, e.g. by ultrasonographic examination. The most serious defects include reduced weight an insertion area of the placenta and infarcts covering more than 6% of the placental area. Extrachorial placentas also have adverse effects. Other macroscopic changes do not appear to be causally associated with intrauterine growth retardation and have been recorded to a comparable extent also in placentas of eutrophic newborns.

Female↗

[Enzymes of the female prostate during the fertile age and after menopause. Comparative histochemical study].

Using histochemical methods, the authors compared the enzymes in the prostate of 19 women of fertile age (15-45 years) and in 9 women after the menopause (53-79 years). In women after the menopause they observed a reduced naphthylesterase activity and also of some other enzymes in the prostatic glands which indicates a possible reduced secretory activity of the prostate in women past reproductive age. Conversely in women after the menopause, with age a marked increase of the activity of lysosomal acid phosphatase in the epithelium of the prostatic ducts was found. "Prostatic" acid phosphatase persisted as regards its activity also in women after the menopause. A drop of activity of dehydrogenases occurs only in women in the most advanced age groups, during the early menopause the findings were similar as during fertile age. The demonstrated differences in enzymes of the prostate in fertile women and after the menopause indicate their different function in the woman's life. These data are the first basis for the possible inclusion of the female prostate among hormone-dependent organs of female reproduction.

Adolescent↗

[Evaluation of fetal status in risk pregnancy using the biophysical profile].

Experiences with using the biophysical profile according to Manning et al. in diagnosing the danger to the fetus in at risk pregnancy are presented. Examinations were carried out in 143 pregnant women. In 33 of them the following parameters were evaluated with respect to the values of the biophysical profile: placental maturity, urinary estriol, term and mode of termination of pregnancy, body weight, body length, and Apgar score of newborns. The authors recommend to extend this diagnostic method so that in interpreting the results it yields not only the overall clinical state of the pregnant woman should be considered but also biological rhythms of physiologic functions of the fetus as well the administration of drugs to the woman in pregnancy.

Female↗