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Biomedical subjects

J Vigne

Publications and source records attributed to J Vigne.

At least 19 recordsLinked to original sources

Random number generation, absorption, and hypnotizability: a brief communication.

Graham and Evans (1977) found that a measure of random number generation (RNG) was related to hypnotizability. In 2 studies, the relationship between hypnotizability and Graham and Evans' RNG (1977) index was examined. In Study 1 Evans' (1981) measures of controlled and automatic absorption were also evaluated. In Study 1 no relationship was found between the measures of absorption or RNG and hypnotizability. Since Study 1 was carried out primarily to evaluate methods for modifying hypnotizability, Study 2 was designed to evaluate RNG measure directly. Study 2 found no consistent relationship between RNG and hypnotizability, or between RNG and measures of the experience of hypnotic depth and nonvolition.

Adolescent

[Study of the regional distribution of inspired gas with radioactive tracers (author's transl)].

Two different techniques are utilized: aerosol with 198Au particles (size 0.5-15 micron) and different gaz mixtures (air; O2 20% + He 80+; O2 60% + N2 40%; O2 60% + He 40%) with 133Xe and registration of the regional distribution along a wash-in (upper, middle and basal) of every lung (gamma camer, computer, Polaroid photographs, scans), performed in three groups of subjects (normal: 5, bronchogenic carcinoma: 11 and chronic bronchitis: 5). Modifications of the airway distribution and blood gas data according to the technical approach (particularly, variations of densities and viscosities) are compared with results in normal subjects.

Adult

Studies of cyclic AMP action using mutant tissue culture cells.

S49 mouse lymphoma cell mutants, each with a specific defect in its ability to generate or respond to cyclic AMP, have been isolated. Analysis of the properties of these cells has begun to provide information on complex and significant biologic problems related to the cyclic AMP system.

Adenylyl Cyclases

Evaluation of the distribution of air and blood in emphysema patients using radioisotopic tracers.

Continuous recording of the respiratory cycle with the simultaneous or sequential radionucleic exploration (gamma camera) of ventilation (133Xe) and perfusion (MAT-99) was performed to determine the V/Q index in regional areas (Polaroid photography, mini-computer, memory visualization system, Benson incremental tracer, etc.) from the level of 1,024 points. An average ratio per sector was calculated and only three median sectors were retained. The wash-in and wash-out curves were traced by computer, and the calculation of the average T 1/2 for the different compartments of each median sector (apex--middle and base) was done in about 22 observations: in 18 diffuse emphysema, 11 of which were associated with giant cystic emphysema (spirometric, plethysmographic and radiographic data), T 1/2 values were greater than those of normal subjects (compartments C1 and C2) in diffuse emphysema and can become indefinable in zones of cystic emphysema. The values of the index V/Q approach the normal in diffuse emphysema with a tendency toward equalization of the ratios from the apex to the base. Extremely large divergence is observed in the elevated V/Q ratios in cystic emphysema.

Adult