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Biomedical subjects

J Volmer

Publications and source records attributed to J Volmer.

8 recordsLinked to original sources

[Chronic persistent hepatitis. Histological and clinical study of different forms of the course of CPH].

Among 4903 liver biopsies were found 96 cases (241 biopsies) of non-active hepatitis persisting for longer than one year (up to 12 years). Three forms of the course of chronic persistent hepatitis could be delimited in morphological terms taking into account clinical laparoscopic and clinical chemical data. The type Ia presents the picture of a largely subsided, lobular accentuated acute virus hepatitis. The type Ib corresponds to a chronic inflammation with emphasis on the portal system without destruction of the limiting plate, without fibrosis and with only slight intralobular involvement. The type Ic is characterized by a portal and slight septal fibrosis with round-cell infiltrates and a slight facultative periportally active inflammation as well as a moderate intralobular mesenchyme reaction. The typing permits a clear subdivision and a differentiated prognosis: 10% of the cases of type Ic pass into an active chronic hepatitis of the type IIa.

Adult

[A tapeworm infection with fatal outcome (author's transl)].

Parasitoses of the intestinal tract are rare in Europe. Their diagnosis is difficult since the general symptoms are frequently only little pronounced or completely lacking. On the other hand, the course of the disease may be fatal. Such cases from the literature and our own observations are intended to call to memory the differential diagnosis of intestinal parasitosis.

Aged

[Erysipelothrix endocarditis (author's transl)].

Following erysipeloid a 46-year-old man fell ill with septicaemia and endocarditis. Treatment with high doses of antibiotics could not prevent his death. Infection with Erysipelothrix rhusiopathiae in man occurs through a skin lesion and only rarely leads to spreading of the agent in the body presenting as arthritis, meningitis, or endocarditis. Erysipelothrix endocarditis is a severe disease leading to widespread destruction of the involved cardiac valves. The aortic valve is most commonly involved. 16 out of 28 patients with erysipelothrix endocarditis reported in the literature died, eleven of them despite treatment with antibiotics.

Animals

[Malignant degenerative osteoneoplastic teratoma of the greater omentum (author's transl)].

A case of teratoma of the greater omentum is reported, which occurred mainly in the form of a highly differentiated osteoma. In the marginal section the tumor showed embryonal structures with signs of degeneration which were found again in metastatic colonization in lymphnodes, pancreas, liver and peritoneum. The malignant component of the neoplasm probably had its origin in the bone marrow of the osteoma.

Humans

Histiocytosis X of lungs and kidneys.

Report on a case of histiocytosis X of the lungs and kidneys. The pulmonary changes occured mainly during the fibrotic phase of the illness. In the kidneys, the process had a distinct granulomatous character with direct transition into a scarring final stage. Unusual was the considerable vascularisation of the pulmonary foci. Because of the large amount of plasma cells, particularly in the renal cortex, an allergic-hyperergic pathogenesis of the illness had to be discussed.

Aged

[Chronic eosinophilic leukemia with eosinophilic granulomas of the lung (author's transl)].

For the first time a report is given on a case of chronic eosinophilic leukemia with occurence of eosinophilic pulmonary granulomas. Even after enucleation of the granulomas eosinophilia remained in the peripheral blood and in the bone marrow, and over a period of 6 years lay at a value of above 50% of the granulocytes. The illness ended with sudden increase in the number of myeloblasts. The autopsy revealed destruction of the bone marrow by myeloblasts, immature and mature eosinophilic granulocytes as well as infiltration of the heart, liver, spleen and kidneys. On the basis of histological, cytological and histochemical examinations of the granulomas, the peripheral blood and the organs after dissection, particularly of the bone marrow, there was good reason to assume common pathogenesis of these changes; it was not however possible to completely exclude an allergically generated cause.

Autopsy

[Bilateral tube carcinoma with unusual involvement of the endometrium].

Report on a case of bilateral, primary carcinoma of the fallopian tube with extensive implantation metastasis of the endommetrium. To judge by the morphological structure of the tumor in the fallopian tubes and in the endometrium, by the nature of the spreading in the mucosa of the uteruscorpus and by the morphology of the intramural fallopian tube sections, the neoplasm is, in differential diagnostic terms, demarcated by a corpus carcinoma of the uterus.

Adolescent