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Biomedical subjects

J W Bass

Publications and source records attributed to J W Bass.

At least 73 records · Page 4Linked to original sources

Decreased circumcision rate with videotaped counseling.

Despite the lack of medical indication for routine circumcision in the newborn, neonatal circumcision continues to be done on the vast majority of male infants in the United States. A trial of videotaped "informed consent" counseling was undertaken to determine whether such counseling could affect the parental choice about circumcision. We studied the circumcision frequency rate (CFR) after videotape counseling. We compared it to the rates following standard oral counseling. Videotaped counseling, in contrast to the standard physician-parent oral counseling, significantly reduced the incidence of parents' requests for routine neonatal circumcision.

Circumcision, Male↗

Neonatal zygomycotic necrotizing cellulitis.

Zygomycosis is a rare infection that should be suspected in any patient with a fulminant necrotizing cellulitis in an area recently covered with adhesive bandages or dressings. Early diagnosis and treatment are essential for patient survival.

Cellulitis↗

Streptococcal pharyngitis. Placebo-controlled double-blind evaluation of clinical response to penicillin therapy.

Forty-four children with a clinical diagnosis of streptococcal pharyngitis had throat cultures performed at the initial evaluation and were assigned by randomization to receive either oral penicillin or a placebo for 72 hours. The treating physician, who remained blind to the treatment regimen, recorded the child's temperature and assessed the presence and severity of other signs and symptoms initially and at 24, 48, and 72 hours. The throat culture was positive for group A beta-hemolytic streptococci in 26 (59%) of the initial study group, and most of these children developed a fourfold or greater titer rise in antistreptococcal antibodies in their serum, confirming the diagnosis of streptococcal pharyngitis. Statistically significant clinical improvement was observed in the group of 11 children who were later shown to have been taking penicillin compared with the group of 15 who had taken the placebo. Significant differences in the presence and degree of fever and severity of symptoms persisted in the placebo-treated group for 48 hours. We conclude that early penicillin treatment of children with streptococcal pharyngitis significantly alters the acute clinical course of the disease.

Adolescent↗

Bacterial and viral pathogens causing fever in infants less than 3 months old.

We studied 182 sick, febrile (temperature greater than 38 degrees C) infants less than 3 months of age, who presented at our Tripler Army Medical Center, Honolulu, during a one-year period, to determine the relative causes of fever in this age group. Blood, cerebrospinal fluid, urine, nasopharyngeal secretions, and stool specimens were cultured for bacterial and viral pathogens. Paired acute and convalescent sera were collected to serologically confirm infection in infants from whom viral isolations were obtained only from the nasopharynx or stool. A viral pathogen was isolated in 75 infants (41%) and a bacterial pathogen was isolated in 27 infants (15%). Nonpolio enteroviruses were the most common pathogens demonstrated. They were isolated from 64 infants (35%), and 40 (62%) of these infants had aseptic meningitis, the most frequently made diagnosis. Urinary tract infection was the most common bacterial infection observed. It occurred in 20 infants (11%) and was most often seen without associated pyuria in uncircumcised male infants. Salmonellosis, the second most common bacterial infection, was observed in six infants (3%), and two of these did not have diarrhea or other gastrointestinal tract symptoms. No infant had septicemia and only one infant had bacterial (group B streptococcal) meningitis.

Bacterial Infections↗

Septic arthritis caused by Kingella kingae.

Kingella kingae is a slow-growing, fastidious gram-negative coccobacillus that is a normal inhabitant of the oropharynx of man, but it has rarely been implicated as a human pathogen. Two cases of septic arthritis caused by this organism are reported along with a review of seven previously reported cases of infections caused by this organism. Bone and joint infections predominate. Gram's-stained smears of pus from bone or joint fluid aspirate have been negative for organisms, and a delay of growth in cultures with initial difficulty in classification of the isolate is characteristic. Kingella kingae organisms have been uniformly sensitive to the penicillins and all other commonly used antibiotics that were tested. Response to treatment was good in all nine patients found to have infections caused by this organism.

Anti-Bacterial Agents↗

Initial antibiotic treatment of purulent meningitis in infants 1 to 2 months of age.

The bacterial cause of purulent meningitis in patients younger than 2 months of age was reviewed. Hemophilus influenzae was the most common organism isolated from infants 1 to 2 months of age. Gram-negative enteric organisms were not shown to cause meningitis in this age group in term infants without neonatal complications. Initial antibiotic therapy for infants in this age group should include ampicillin sodium and chloramphenicol sodium succinate.

Ampicillin↗