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Biomedical subjects

J W Groothoff

Publications and source records attributed to J W Groothoff.

95 records · Page 6Linked to original sources

[Milker's fever, an occupational disease on the increase].

In order to obtain a better picture of the course of dairy farm fever, a leptospirosis caused by hardjo, an inquiry by means of questionnaires was conducted into its symptomatology and its trade-connected risk factors. The inquiry was performed in 32 seropositive dairy farmers and a matched-pair control group. All persons involved were living or working on contaminated farms. Of the seropositive persons 63% reported symptoms suggestive of dairy farm fever and in all of them there had been obvious fatigue of an extreme and protracted nature and an often lengthy period of recovery. The results of this investigation suggest underreporting of this disease. Besides vaccination and/or treatment of the dairy cattle adjustment of operations on dairy farms (e.g. wearing personal protection) might be feasible for prevention. The causal relationship between occupation and dairy farm fever indicates an occupational disease.

Agglutination Tests↗

[The dementia syndrome in the clinical practice of 15 family physicians. A pilot study of the prevalence in the Zwolle area].

A pilot investigation among 15 general practitioners in the region of Zwolle has been carried out in order to obtain an indication as to the prevalence of the dementia syndrome among noninstitutionalized elderly people. According to the general practitioner--on the basis of the Clinical Dementia Rating--4.4% of the population of people of 65 years and older display the symptoms of dementia, a percentage that is low compared with foreign studies. There is a striking difference in the prevalence rate between urban (2.8%) and rural (5.7%) populations. The most obvious explanation for this difference is that in rural areas there is more informal care and a larger degree of tolerance of demented elderly people, which helps prevent institutionalization. This assumption is supported by an identical difference in the admission rate to nursing homes. As a person becomes older, the chance that he/she will suffer from the dementia syndrome increases, although the increase is not a steady one. Despite the well-recognized necessity for thorough medical examination of demented elderly people, it is only carried out to a small degree. The authors argue in favour of more extensive research into the prevalence rate of the dementia syndrome, which will promote policy making with regard to medical practice and the planning of care facilities.

Aged↗

Late somatic and psycho-social consequences of renal insufficiency in children.

The aim of the project was to establish the somatic and psycho-social consequences in adulthood of paediatric end-stage renal disease (ESRD). A long term follow up study of all Dutch patients who started renal replacement therapy at age 0-15 years between 1972 and 1992 and who were born before 1979 was undertaken. The study was performed between 1998 and 2000. About 25% of patients had died at time of investigation. Cardiovascular abnormalities were prominent in both transplanted and dialysis patients and cardiovascular disease was also found to be the most prominent cause of death. Skeletal disorders as a result of metabolic bone disease accounted for most frequent occurring disabilities. The risk for malignancies was 10-fold that of the normal population. Mean IQ and educational attainment were low as compared to the normal population. The overall quality of life was good, despite the co-morbidity and disabilities. Adverse outcomes were in nearly all cases related to a prolonged period of dialysis in the past and to (current) hypertension, not to the state of dialysis at time of investigation.

Adolescent↗

Persistent tachypnea in children: keep pulmonary embolism in mind.

PURPOSE: Tachypnea in children is associated with respiratory disorders and nonrespiratory disorders such as cardiac disease, metabolic acidosis, fever, pain, and anxiety. Pulmonary embolism is seldom considered by pediatricians as a cause of tachypnea. PATIENTS AND METHODS: Three children of various ages with persistent tachypnea are described: a girl after orthopedic surgery for kyphoscoliosis, a boy with nephrotic syndrome, and a neonate with Hirschsprung disease. Other causes of tachypnea were diagnosed and treated before pulmonary embolism was considered. RESULTS: Ventilation-perfusion scanning appeared to be highly probable for pulmonary embolism in these patients. Anticoagulant therapy was started. CONCLUSION: Pulmonary embolism should be kept in mind in children with tachypnea, especially when other risk factors for venous thromboembolism are present, to avoid delay in anticoagulant treatment and a fatal outcome.

Anticoagulants↗