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Biomedical subjects

J W Ludwig

Publications and source records attributed to J W Ludwig.

25 records · Page 2Linked to original sources
PubMed1979

Use of metrizamide in coronary arteriography.

In the investigation of the arteriae coronariae by means of angiography, a comparative study has been done of two contrast media in the same patients, by injecting these media in a randomized order. The contrast media are sodium methylglucamine diatrizoate (10:66) and metrizamide, both used in a concentration of 370 mg I/ml. The reaction of the heart was registered in different ways with which also the influence on the blood pressure was measured. The quality of the films was judged by persons who were not acquainted with the sequence of the injections.

Adult↗
PubMedDate not supplied

Ultrasonic duplex scanning in atherosclerotic disease of the innominate, subclavian and vertebral arteries. A comparative study with angiography.

Ultrasonic duplex scanning of the vertebral artery has a sensitivity of 0.80 and a specificity of 0.83 for the detection of an obstructive lesion of 50% or more at the site of the ostium. For the subclavian arteries these values are respectively 0.73 and 0.91. For both vessels the test has a very high negative predictive value of respectively 0.96 and 0.97. Therefore duplex ultrasound scanning is a reliable test in screening patients suspected of multi-level atherosclerotic disease of the extracranial cerebral vessels. The problem remains in classifying the degree of stenosis. In the case of the vertebral artery the sample volume of the pulsed Doppler is usually too large in relation to the vessel diameter. In the case of the subclavian and innominate artery one of the main problems is the range of the pulsed Doppler system. A subclavian steal syndrome is easily diagnosed without any special test.

Angiography↗
PubMedDate not supplied

Digital subtraction angiography of the carotid bifurcation.

This report described the results of digital subtraction angiography (DSA) in the diagnosis of arteriosclerotic disease of the extracranial arteries, especially the distal part of the common- and proximal part of the internal carotid arteries compared to the catheter angiography. 50 patients underwent DSA and conventional angiography. In 85% of the patients, the quality of the DSA examination was good. For the internal carotid arteries the standard sensitivity was 91% and the standard specificity 93%. In all patients both vertebral arteries were visualized on DSA. All patients underwent the non-invasive tests (OPG, Doppler, Duplex). These tests and the DSA together cannot always replace the catheter-angiography in case of carotid pathology. We started an investigation to assess in which cases the catheter-angiography can be replaced by DSA to arrive at the same diagnosis. The preliminary results indicate that replacement of the conventional angiography by DSA is possible in 80% of this patients group.

Adult↗