Biomedical subjects
Publications and source records attributed to J W McCrory.
Fifty children underwent inhalation induction of anaesthesia with isoflurane and nitrous oxide in oxygen with or without the addition of 5% carbon dioxide. Addition of carbon dioxide resulted in more rapid induction and significantly reduced the incidence and severity of airway related problems.
We have investigated the need for a loading dose of local anaesthetic before continuous extradural analgesia. After a standard test dose, patients received 0.08% bupivacaine 8 ml, isotonic saline 8 ml or nothing. A continuous infusion of 0.08% bupivacaine 20 ml h-1 was then commenced. The mean times to onset of satisfactory pain relief were similar in the first two groups, but prolonged significantly in the third. This group also required more interventions for inadequate analgesia, although not significantly so. Mean time to achieve highest level of block was significantly shorter in the first group.
We studied four different techniques of preoxygenation in 20 healthy volunteers, by continuous analysis of respired gases. Three minutes of tidal breathing from a Magill breathing system or four vital capacity breaths from a non-rebreathing system were found to be equally effective, whereas four vital capacity breaths from a Magill breathing system were less effective. Maximal expiration before application of the face mask resulted in improved oxygenation when four vital capacity breaths were taken from a Magill system.
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