PubMed Health⌕ Search

Biomedical subjects

J W Walike

Publications and source records attributed to J W Walike.

At least 19 recordsLinked to original sources
PubMed1990

Demineralized bone. Implant resorption with long-term follow-up.

The osteoinductive properties of demineralized bone have stimulated its use in facial skeletal augmentation and reconstruction. Demineralized bone has been shown to induce phenotypic conversion of mesenchymal cells into osteoblasts, with bone formation within 29 days (osteoinduction). In this clinical study, 75 demineralized bone implants were followed up from 1 to 48 months (average follow-up, 14.3 months). There were 41 major dorsal implants, with an average degree of resorption of 50.7%. Eight dorsal implants were followed up for more than 24 months, with an 82.5% degree of resorption. Overall resorption for all implants was 49%. Major factors contributing to implant resorption included lack of surrounding mesenchymal cells and inadequate contact between host tissue and bone-inducing surface area. Other factors included infection, poor vascularity, and compression of the implant. Demineralized bone has an unacceptably high resorption rate and should only be used in highly selective cases where the implant can be positioned in a site rich in primitive mesenchymal or bone-forming cells.

Bone Density↗
PubMed1985

The 'note flap'.

A versatile local skin flap for the closure of facial defects is presented. A tangent is drawn to the edge of a circular defect parallel to the relaxed skin tension lines for a distance of 1.5 diameter (d); a second line of length d is drawn at 50 degrees to 60 degrees to the first to create a triangular flap. The final flap design when drawn resembles an eighth note. The tip of the flap is de-epithelialized to facilitate closure. Two opposing flaps can be used for a larger defect if desired. In a series of 20 consecutive patients, the mean length of the first side of the flap was 1.4d, the length of the second was 1.1d, and the mean tip angle was 50.3 degrees. The area of this average flap is approximately 75% of the area of the circular defect. Skin deformation measured on piglets showed the major tension vector to be perpendicular to the tangential side of the triangular flap.

Animals↗
PubMed1979

Suturing technique in facial soft tissue injuries.

This article has presented suturing techniques and instrumentation and suggestions that we have found to be helpful in the management of facial soft tissue injuries. The reader is encouraged to practice suture and knot tying techniques on fresh pigfeet, which are readily accessible and inexpensive and approximate the characteristics of human skin.

Debridement↗
PubMed1979

Management of acute ear infections.

The differential diagnosis between the usual acute otitis externa and acute suppurative otitis media is presented. Other important and sometimes frequently seen entities that present as infections in the ear are also discussed. It is emphasized that a patient complaining of ear pain with normal findings on examination must be more thoroughly investigated because of the possibility of a more ominous condition such as carcinoma of the pharynx.

Acute Disease↗
PubMed1979

Evaluation and treatment of acute bleeding from the head and neck.

Three entities that can cause life threatening bleeding in the head and neck are described: epistaxis, post-tonsillectomy bleeding, and post-tracheostomy bleeding. It behooves all physicians operating in this area and emergency room physicians and personnel to be acquainted with the diagnosis and management of these situations.

Acute Disease↗
PubMed1978

Management of intraoral injuries.

Primary closure of intraoral wounds can be done up to 24 hours after the injury. A mucosal seal decreases the possibility of infection and allows the wound to heal more rapidly and less painfully than a wound left open to heal by secondary intention. Defects of the lips must be closed with exact alignment of the vermilion-cutaneous margins. Nerve repairs must be done without tension at the repair site. Parotid duct repairs are mandatory to prevent cyst and fistula formation. Anterior permanent teeth may be replanted.

Adult↗
PubMed1977

Relative lactose intolerance. A clinical study of tube-fed patients.

A relative intolerance of lactose was demonstrated in 14 of 16 patients receiving nasogastric tube feedings following surgery for head or neck carcinoma. Two liquid diets differing only in the presence or absence of lactose, were administered for eight to 20 days per patient in a double-blind crossover study. Increased stool frequency, decreased stool consistency, and more frequent flatulence, borborygmi, and distention were found with the lactose diet, although classic lactose intolerance (plasma glucose rise of less than 26 mg/dl) was indicated in only two patients. Differences between amounts and times of peak rise following the glucose tolerance test and lactose tolerance test for each patient indicated the advisability of locating patients on a continuum of ability to hydrolyze lactose. The results indicate that lactose should be reduced or eliminated from tube-feeding diets to improve patient tolerance and comfort and to reduce diarrhea.

Aged↗