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J Wane

Publications and source records attributed to J Wane.

3 recordsLinked to original sources
PubMed2006

Reference values for serum protein and electrolyte study from Rwanda.

OBJECTIVE: To estimate reference values of serum proteins and electrolytes in a student population in Butare, Rwanda (altitude: 1768 m; barometric pressure: 629 mm Hg). DESIGN: A laboratory based cross-sectional study. SETTING: The units of physiology and clinical chemistry, department of medical biology, Butare University Hospital and Faculty of Medicine, National University of Rwanda, from February 2002 to May 2003. SUBJECTS: Young healthy adults were selected randomly from the students of the National University of Rwanda, using Epi-Info 6.04 software. RESULTS: The results mean and reference range (2.5th-97.5th percentile) in brackets - are as follows: total proteins: male: 7.3 (6.3-8.4) g/dL, female: 7.3 (6.5-8.5) g/dL; albumin: male: 4.3 (3.1-5.2) g/dL, female: 4.1 (3.2-5.0) g/dL; globulins: male: 3.1 (2.0-4.2) g/dL. female: 3.2 (2.1-4.2) g/dL; sodium: male: 138.5 (130-147) mmol/L, female: 139.8 (132-153) mmol/L; potassium: 4.0 (3.1-5.0) mmol/L both in male and in female; chloride: males: 104.4 (96-112) mmol/L, females: 106.1 (98-114) mmol/L; phosphates: male: 1.13 (0.65-1.59) mmol/L, female: 1.17 (0.71-1.52) mmol/L. CONCLUSION: The values of serum proteins and electrolytes are comparable to classical sea level values; however there is a slight increase in serum chloride.

Adult↗
PubMed1994

Therapeutic effect of an anti-HIV candidate vaccine.

A chimpanzee infected with the HIV since 8 months and presenting regularly with antigenemia was inoculated with a candidate vaccine. It received 3 doses, one dose every 15 days. Thirty days after the third injection, we noted the disappearance of the HIV antigens in the serum and its persistence in the lysate of the cells. We noted also a strong precipitation reaction both in the tube and in the gel between the antibodies and the antigens released by the lysis of the cells. The analysis of this precipitate demonstrated that it was constituted of immune complexes in which the antibodies were of high affinity. At the 240th day after the third injection of the candidate vaccine we noted the disappearance of the HIV antigens in the lysate of cells as well. From these results, we conclude that the candidate vaccine we tested can elicit high affinity antibodies able to clear the HIV antigens and destroy the cells containing the HIV antigens probably with the help of specific killer cells.

AIDS Vaccines↗