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J Wartenberg

Publications and source records attributed to J Wartenberg.

26 records · Page 2Linked to original sources
PubMedDate not supplied

[T and B lymphocytes and serum alpha 1-antitrypsin activity in children with bronchial asthma treated with broncho-vaxom].

The aim of this study was to evaluate an effect of Broncho-Vaxom treatment on T and B lymphocytes and serum alpha 1AT in children treated at "Zuch" sanatorium in Szczawno-spa. The trial involved 46 school aged children suffering from infectious or infectious-atopic asthma. The post-Broncho-Vaxom treatment values for T lymphocytes were significantly higher in infectious, and significantly lower for B lymphocytes in infectious-atopic asthma. Serum alpha 1AT activity in children suffering from infectious asthma decreased significantly after the treatment. A correlation between the efficacy of the treatment and the lymphocyte percentage was observed. In children with very effective clinical results of Broncho-Vaxom treatment, the significant increase in T lymphocyte, and decrease in B lymphocyte populations was observed. Changes in T and B lymphocyte percentage were analysed in respect to alpha 1AT pre-treatment activity. In children with high alpha 1AT value, T lymphocytes after the treatment increased significantly in infectious, and B lymphocytes decreased significantly in infectious-atopic group.

Adjuvants, Immunologic↗
PubMedDate not supplied

[Thyroid anti-membrane antibodies and antithyroglobulin antibodies of children in the city and province of Wrocław].

The purpose of the work was an assessment of thyroid function and determination of the development of antithyroid autoantibodies in children undergoing iodine prophylaxis after Chernobyl disaster. The level of T3 and T4 was determined by the RIA method, that of TSH by th immunoenzymatic method using Abbott kit, while antimembrane and antithyroglobulin antibodies were determined by the immunoenzymatic method using HTL-Plastomed kit. The studies were carried out in 844 children (433 boys and 411 girls) aged from 4 to 16 years, the selection of whom was described in our earlier report (12). Our studies demonstrated an increased level of T3 in 15.6% of the studied children and increased level of T4 in 12.7% of the cases. In most children the levels of hormones and TSH in the serum were normal. The antimembrane antibodies ATMA were present in 1.9% of the children (0.5% of the boys and 3.4% of the girls), while antithyroglobulin antibodies were found in 2.2% of the studied population (0.9% of the boys and 3.4% of the girls). No correlation was found between clinical picture, size of goitre, hormone level and the presence of thyroid autoantibodies. The studies indicate that radioactive contamination and iodine prophylaxis failed to cause permanent thyroid function disturbances in the studied population. The children in whom autoantibodies or abnormalities in hormone levels were found require further observation.

Adolescent↗