Biomedical subjects

J Weisser

Publications and source records attributed to J Weisser.

24 records · Page 2Linked to original sources

PubMed1978

[Familial paroxysmal choreoathetosis. Clinical course, L-dopa-effect (author's transl)].

The clinical course of two boys with familial paroxysmal choreoathetosis was traced. As far as the medical history could be retrieved, their family has been affected by this disease for three generations. Except for this disorder, the patients' development and psychophysical state are unremarkable. Both boys responded well but at times incompletely to anticonvulsants. Therefore L-Dopa was introduced to the therapeutic regime of the younger, more severely affected boy. L-Dopa caused an appreciable decline of the frequency of the paroxysms.

Adolescent↗

PubMed1976

[Transporation of high-risk new borns (author's transl)].

Organisation and results of a mobile intensive unit for high-risk neonates are reported. Within one year 134 transporations were required. Temperatures of the incubator from the beginning and the end of the transports as well as body temperature, blood gas analysis and blood sugar concentration of the neonates at arrival were choosen for quality control. The mortality of the newborn infants after admission was evaluated. The indications for transportation of severely ill infants are listed and the transport equipment is described.

Blood Gas Analysis↗

PubMed1975

[Mobile intensive-care-unit for transportation of premature and newborn babies at risc (author's transl)].

This is a technical report on a specially equipped ambulance for transportation of high-risk, seriously ill neonates. A mobile neonatal intensive-care-unit operating independently of the car utilized an Ohio-transport-incubator with 12V-DC portable power pak and collapsible stand, battery-operated ECG-monitor with optical and acoustical signal, a ECG-monitor with optical and acoustical signal, a battery-operated infusion pump, a Bird-respirator mark 8 with oxygen-blender, nebulizer and infant circuit with modification for PEEP as well as additional accessories. Ambulance-duty service is guaranteed by the German Red Cross (DRK) to facilitate transfer at any time, while skilled personal (physician, nurse) of the intensive care ward in on 24 hs call.

Electrocardiography↗

PubMedDate not supplied

Inhibition of RNA- and DNA-synthesis by citrinin and its effects on DNA precursor-metabolism in V79-E cells.

1. The RNA synthesis of V79-E cells was inhibited by the mycotoxin citrinin time- and concentration-dependently. 2. Among the different RNA species mainly the rRNA synthesis was found to be inhibited by 200 microM citrinin. 3. At different precursor concentrations DNA synthesis was inhibited by citrinin after 30 min at least whereas labelling of the acid soluble fractions was found to be 3-fold higher than in untreated cells. 4. Remarkable perturbation of the DNA precursor metabolism, including release of precursor into the medium, was found to occur during citrinin treatment.

Animals↗

PubMedDate not supplied

[Glutaric acidemia/glutaric aciduria I as differential chorea minor diagnosis].

Glutaracidemia/glutaraciduria type I is an acute or subacute neuropathic disorder of infancy or early childhood. The following symptoms characterize the clinical course: macrocephalus present at birth, cerebral atrophy revealed by CT or MRI scans, most striking in the frontal and temporal lobes, choreoathetosis and dystonia as neurological handicaps. The deficiency of glutaryl-CoA-dehydrogenase leads to glutaracidemia and glutaraciduria. It is reported on a three year old girl. The glutaraciduria is an important differential diagnosis to chorea minor.

Child, Preschool↗

PubMedDate not supplied

[Transmission of the human immunodeficiency virus by a dry heat-treated Factor VIII concentrate?].

Short presentation of the common procedures to avoid transmission of human-immunodeficiency-virus (HIV) by hemoderivates especially clotting-factor-preparations. The stepwise seroconversion (ELISA, IFT, Western-blot) of HIV is shown in a 7 5/12 ys old boy with hemophilia A after administration of a dry-heated factor VIII-preparation. Seven similar observations were reported in the literature. On the other hand HIV-seroconversion could not be observed during treatment with wet-heated factor VIII-preparations. In consequence only wet-heated factor VIII-preparations and factor IX-preparations respectively should be administered to hemophiliacs without HIV-antibodies. By this precaution transmission of non-A, non-B-hepatitis may be avoided simultaneously.

Acquired Immunodeficiency Syndrome↗