Biomedical subjects

J Wendlova

Publications and source records attributed to J Wendlova.

3 recordsLinked to original sources

PubMed2006

Why does depression develop in complicated osteoporosis?

PATIENTS AND METHODS: In a prospective study we observed which female patients developed depression following an acute and painful vertebral fracture. For the statistical evaluation of questionnaires we chose randomly 32 patients with depression (out of 33 patients) aged 51-73, and 32 patients without depression (out of 44 patients) aged 52-70. THE AIM OF THE STUDY: To verify the hypothesis that the patients with more traumatic experience in the anamnesis (Questionnaire No. 1) are more depression prone following the osteoporotic vertebrae fractures and their character features are typical for subjects with higher emotional vulnerability (Questionnaire No. 2). STATISTICAL ANALYSIS: 1. Questionnaires 1 and 2 were evaluated by two statistical methods: a) automatization of mathematical and statistical estimates and tests based on binomial distribution; b) ADALINE Programme. 2. Assessment of relative risk for developing depression. RESULTS AND CONCLUSION: We recommend to use questionnaires No. 1 and 2 in female patients with acute painful vertebrae fractures to select patients with the risk of depression development. These patients should be followed more frequently as outpatients and in case of first clinical symptoms of depression should be recommended for special psychiatric care. Early therapy of depression enables to accelerate the mobilisation, rehabilitation and resocialisation of patients, to improve the quality of their lives and to reduce the costs of analgetic treatment of pain, sedatives and rehabilitation (Tab. 10, Fig. 2, Ref. 17).

Aged↗

PubMed2005

Draft design of a rehabilitation aid for patients with acute painful fractures of vertebrae.

AIM OF THE STUDY: To model the influence of abduction and adduction of the upper limb on the spinal load with the help of the laws of theoretical mechanics and the application of its results in clinical medicine. BIOMECHANICAL SOLUTION: Biomechanical model of an upper limb is demonstrated as a construction consisting of a lever arm and a joint connection in articulation of the shoulder joint. CONCLUSION: Our application of results of the spine load modelling in relation to excess upper limbs load: A) designing a methodology of active therapy aimed at exercising upper limbs for osteoporotic patients, B) the application of basic principles of motoric activity in daily life, C) the draft design of a rehabilitation aid for patients with acute painful fractures of vertebrae in the thoracic area (Fig. 5, Ref. 17).

Biomechanical Phenomena↗

PubMed2000

[Bone density and its quality].

The paper presents the newest knowledge on bones quality, which becomes the main criterion for evaluation of fracture risks and osteoporosis treatment effects. It is necessary to develop new methods of measurement and quantification of bones quality, with regard to the properties of all bone structures, not solely the bone mineral density (BMD) as it was until now. From the most recent studies follows: 1. bone stiffness depends not only on BMD but also on the bone quality, 2. antiosteoporotic treatment can reduce the fracture incidence without significant rise of BMD, 3. BMD is not always an reliant marker of all treatment procedures efficiency in osteoporosis, 4. it is necessary to develop new diagnostic methods for bone quality quantification with the possibility of exact fracture risk determination, 5. in future the influence of antiosteoporotic drugs on bone quality, i.e. on all structures, not only BMD, will be studied. (Ref. 8.)

Bone Density↗