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Biomedical subjects

J Wilczyński

Publications and source records attributed to J Wilczyński.

9 recordsLinked to original sources
PubMed1979

Detection and tissue localization of components of the immune complex in animals infected and immunized with influenza virus.

Mice previously vaccinated or convalescents after infection with mouse-adapted influenza virus were challenged by various routes with live or inactivated virus. The components of the immune complex (antigen-antibody-complement) could be detected by immunofluorescence in lungs, kidneys, and heart. The frequency of positive immunofluorescence reaction was related to serum antibody level and, to some extent, to the route the animals were challenged.

Animals↗
PubMed1979

Autoantibodies in human sera after vaccination with inactivated influenza vaccine.

Sera from persons vaccinated with inactivated bivalent influenza vaccine were tested for the presence of smooth-muscle antibodies (SMA) and antibodies against the brush border of proximal renal tubuli (ABBA). The autoantibodies were found with the highest frequency in persons repeatedly vaccinated with the vaccine.

Antibodies, Viral↗
PubMed1979

Clearance of antibody and complement in serum after challenge of mice previously vaccinated or infected with influenza virus.

Mice previously vaccinated or convalescent after infection with mouse-adapted influenza virus were challenged by various routes with live or inactivated virus. The levels of haemagglutination inhibiting and complement-fixing antibodies and complement in serum were found to decrease distinctly within several hours after challenge: the reconstitution to initial levels occurred within three days.

Animals↗
PubMed1976

RS virus components. I. Isolation and purification.

RS virus was centrifuged in zonal rotor on 55% sucrose cushion. Three layers were collected: light (RS-LL) containing complement-fixing antigen, medium (RS-ML) containing both complement-fixing and virus particle antigens, and heavy (RS-HL) containing antigen associated with the virus particle. RS-LL was chromatographed on Sephadex G-200 column. Two peaks were obtained, containing complement-fixing activity (RS-LL-1 and RS-LL-2). After sonication (20 Hz, 30 min) RS-ML and RS-HL also were chromatographed on Sephadex G-200 column. Two protein peaks were obtained from each layer (RS-ML-1 and RS-ML-2 from medium, and RS-HL-1 and RS-HL-2 from the heavy layer), corresponding to RS virus proteins.

Antigens, Viral↗
PubMed1976

RS virus components. II. Antigenicity.

Rabbits were immunized with RS virus components, isolated as described previously. The sera were tested by neutralization, double diffusion and complement-fixation. RS virus components induced low titers of precipitating and complement-fixing antibodies, and failed to stimulate the neutralizing antibodies.

Animals↗