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Biomedical subjects

J Witvoet

Publications and source records attributed to J Witvoet.

At least 19 recordsLinked to original sources

Press-fit metal-backed alumina sockets: a minimum 5-year followup study.

Two hundred thirty-four consecutive alumina-on-alumina hip replacements using a press-fit metal-backed socket, performed on 214 patients (98 women, 116 men) have been reviewed. These included 201 primary procedures and 33 revision procedures. The median age of the patients at the time of surgery was 62 years (range, 21-83 years). Fourteen patients (16 hips) died from unrelated causes. Eleven patients (11 hips) underwent a total hip arthroplasty revision for recurrent dislocation (one hip), deep infection (two hips), fracture of alumina femoral head (one hip), persistent hip pain (one hip) and aseptic loosening (six hips). The survival rate after 9 years was 93.4% when revision of the prosthesis was considered the end point, and 97.4% if revision of the prosthesis for aseptic loosening was considered the end point. Results were assessed in the surviving patients with a minimal 5-year followup (170 patients, 184 hips). At the median followup of 7.8 years, the average Merle d'Aubigné and Postel score had improved from 11.9- to 17.7. Results were graded as excellent in 148 hips (80.5%), very good in 31 hips (17%), good in two hips (1%), and fair in three hips (1.5%). Radiologic data were documented for 134 patients (143 hips). Three sockets (2%) had a complete and nonprogressive radiolucent line less than 1-mm thick, one stem (0.7%) had lucencies involving five zones, and two stems (1.4%) had isolated femoral osteolysis. Neither component migration nor acetabular osteolysis were detected. A press-fit metal-backed socket may offer a good solution for alumina socket fixation when combined with a careful surgical technique of implantation.

Adult↗

Total knee replacement after failed tibial osteotomy: results of a matched-pair study.

Sixty-three total knee replacements were performed after a failed tibial osteotomy. The goal of this study was to compare the perioperative problems and the outcome of this group of patients (study group) to a group of patients with primary arthroplasties matched for age, gender, length of follow-up, weight, and preoperative Charnley class. Operative problems were more frequently encountered in the study group, with 7 tibial tubercle elevations and 15 lateral retinaculum releases needed, whereas lateral retinaculum release was necessary for only 1 knee in the control group. Outcome was assessed using both the International Knee Society (IKS) scoring system and Hospital for Special Surgery (HSS) knee score. The follow-up period averaged 4.6 years. The IKS score of the control group was significantly higher, averaging 80.9 +/- 13.8, whereas it was 74.4 +/- 14.8 for the study group (P = .0001). Among the parameters included in the knee score, only pain was significantly different with the control group (P = .03). The IKS function score and the HSS score were not statistically different. Conversion of a failed tibial osteotomy is a technically demanding procedure. Careful preoperative planning is needed. Results, especially on pain, appeared to be inferior to those for primary arthroplasties.

Aged↗

Femoral head osteonecrosis after bone marrow transplantation.

Thirty-five patients with bilateral osteonecrosis of the femoral head after bone marrow transplantation were reviewed retrospectively. The median age at the time of transplantation was 26 years. The first symptoms occurred within 2 years of transplantation. At presentation, 18 of the patients reported pain in both hips, 17 had symmetric radiographic lesions, and 39 of the hips had collapsed. Medical treatment was indicated initially. At the final examination before surgery (median, 3.5 years), 31 patients had bilateral hip pain, 22 patients had symmetric radiographic lesions, and 56 of the hips had collapsed. Fifty-seven of the hips required surgery, including one open drainage, four core decompressions, six cup arthroplasties, and 46 primary total hip replacements. Six hips (four core decompressions; two cups) later underwent total hip replacement revision, and a deep infection developed in one. By considering the requirement of a total hip replacement as a failure of conservative treatment, the rate of survival of the femoral head was 30% 5 years after the transplant. There was no significant difference between the Ficat grades, except for Grade 0, which showed a higher survival rate. The study of the specific features of the osteonecrosis may lead to the recommendation of primary total hip arthroplasty after failure of the medical treatment.

Adolescent↗

[Bilateral total hip prosthesis in osteopetrosis. Apropos of a case. Review of the literature].

PURPOSE OF THE STUDY: The authors report an original case of Albers-Schönberg's disease and describe its surgical treatment. MATERIAL: Comparison between roentgenogram of the pelvis at the age of 9 and 46 years showed the original evolution of coxa vara in a case of osteopetrosis. A 46 year old male had severe pain and instability in both hips related to numerous problems consisting of: 1) on the right side: subtrochanteric femoral non-union after repeated fractures, head and neck femoral disappearance associated to dislocation. 2) on the left side: acetabular dysplasia, osteoarthritis and subtrochanteric femoral fracture that had fusionned. Total hip arthroplasty was performed on both hips. RESULT: Clinical result was good in both hips (PMA score = 6-6-4) at the latest follow-up (four years on the left side and three years and four months on the right side). The surgical procedures were difficult because of the hardness and brittle character of the bony substance and because of non unions and deformities. Special care was required to avoid shattering femoral diaphysis and false routes during creation of a new medullary canal. CONCLUSION: Total hip prosthesis represents a functionnal salvage procedure in patients with Albers-Schönberg's disease.

Arthroplasty, Replacement, Hip↗

Ceramic-ceramic and metal-polyethylene total hip replacements: comparison of pseudomembranes after loosening.

We made a semiquantitative study of the comparative histology of pseudomembranes from 12 loose cemented ceramic-ceramic and 18 metal-polyethylene total hip replacements. We found no significant difference in cellular reaction between the two groups, but there was a major difference in the origin of the particulate debris. In the metal-polyethylene group, polyethylene of articular origin was predominant, while in the ceramic-ceramic group the cellular reaction appeared to be a response to zirconia ceramic particles used to opacify cement used for fixation. Isolation and characterisation of the debris showed that the zirconia particles formed the greatest proportion (76%) in ceramic-ceramic hips, while alumina debris of articular origin formed only 12%. Our study has indicated that aseptic loosening of ceramic cups is not due to a response to debris generated at the articular interface, but to mechanical factors which lead to fragmentation of the cement.

Bone Cements↗

Tibial tunnel enlargement after anterior cruciate ligament reconstruction by autogenous bone-patellar tendon-bone graft.

This retrospective study was designed to evaluate changes in the diameter of the tibial tunnel over time following the reconstruction of the anterior cruciate ligament (ACL) with a bone-patellar tendon-bone autograft in 44 patients. The changes in the geometry of the bone tunnels were measured radiographically during the immediate postoperative period and at time intervals between 3 and 36 months after surgery. The dimensions at 1 year were correlated with the 1-year clinical results. The distance between the sclerotic margins of the tibial tunnel was measured at the distal tunnel exit on the medial tibial cortex, in the middle of the tunnel, and proximally at the level of the joint line. The dimensions were calculated by using a magnification factor determined by reference to the interference screw of known diameter located within the tunnel. The position of the centre of the tibial tunnel with regard to Blumensaat's line was also measured. The average tunnel diameter at the proximal tibial exit increased from 12 +/- 1.9 mm (mean +/- standard deviation) postoperatively to 14 +/- 2.2 mm at 3 months. The average proximal tunnel diameter did not significantly change from 3 months to 2 years, and then decreased to 13 +/- 2.4 mm at 3 years. At 1 year, most of the patterns of osteolysis were of the cone type (57%), followed by the cavity type (40%) and line type (3%). The degree of osteolysis was not related to the tibial tunnel position with respect to Blumensaat's line. There was no correlation between the changes in tunnel diameter and either the IKDC score or the residual joint laxity measured by a KT-100 arthrometer. The aetiology of tunnel enlargement is currently unknown. Possible factors responsible for bone resorption include micromotion of the graft relative to the tunnel wall, leading to an inflammatory response in the tunnel, or stress shielding of the tunnel wall proximal to the interference screw.

Adolescent↗

Avascular necrosis of the femoral head after allogenic bone-marrow transplantation. A retrospective study of 27 consecutive THAs with a minimal two-year follow-up.

After an allogenic bone-marrow transplant, avascular necrosis of the femoral head may affect young adults, producing destructive lesions which require hip replacement. We have reviewed 27 consecutive such total hip arthroplasties (THA) at a minimal follow-up of two years. Of these, 20 were primary operations for Ficat (1985) stage-III and stage-IV lesions, and seven were revisions after the failure of previous surgery. The median age at operation was 30 years (17.5 to 44). The prostheses had a cemented, collared titanium-alloy stem, an alumina-alumina joint, and a press-fit socket. Seven had a titanium-alloy metal back and 20 had all-alumina cups of which six had to be cemented. At an average follow-up of five years, no patient had been lost to follow-up. One had died from septicaemia after two years and another with chronic graft-versus-host disease developed a deep infection 2.5 years postoperatively and had a successful revision. There were no revisions for aseptic loosening. The clinical results on the Merle d'Aubigné++ and Postel (1954) scale were very good or excellent in 23 hips (88%), good in one and fair in two. Ten hips showed incomplete acetabular radiolucencies less than 1 mm thick, but there were no radiolucent lines around the stems. We conclude that for these difficult patients THA with ceramic joints and careful technique provides the best short- and medium-term option after the failure of medical treatment.

Adolescent↗

Roentgenographic and magnetic resonance imaging of anterior cruciate reconstruction using a patellar tendon graft--correlations with physical findings.

The purpose of this study was to evaluate the influence of the graft positioning on the clinical outcome and magnetic resonance imaging (MRI) signal of the graft following anterior cruciate ligament (ACL) reconstruction using the central one-third of the patellar tendon. Twenty-two patients with a chronic anterior instability underwent a modified Marshall-MacIntosh procedure, while 27 with a subacute torn ACL had an ACL reconstruction using a free bone-patellar tendon-bone graft. The patients were retrospectively reviewed with a 1.8-year average follow-up (1-3 years). The clinical result was evaluated through the comparative range of motion and the residual laxity as measured with the KT 1,000 arthrometer. The roentgenographic analysis was performed from anteroposterior (AP) and mediolateral (ML) views, made first on one-leg standing with the knee at 30 degrees of flexion, and secondly at "zero" extension with active quadriceps contraction. Lines were drawn to visualise the location of the tibial and femoral tunnels in relation to the tibial plateaus and the intercondylar roof represented by Blumensaat's line. The analysis of the lateral MRI views of the graft allowed discrimination between homogenous and heterogenous graft signals. On lateral roentgenograms of normal knees, it was found that Blumensaat's line crossed the surface of the medial tibial plateau at 30% +/- 9% of its sagittal width (20%-40% range), demonstrating the variability of intercondylar roof inclination. The range of motion was normal in 34 patients (group I), 9 patients had a flexion deficit (group II), and 6 exhibited an extension deficit (group III). The residual laxity was similar in each group (P > 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

Anterior Cruciate Ligament↗

[Radiologic and MRI evaluation of intra-articular ligamentoplasty using a patellar tendon. Correlations with anatomical results].

INTRODUCTION: the purpose of this study was to evaluate the influence of the graft positioning on the clinical outcome and MRI signal of the graft as well, following ACL reconstruction using the central one-third of the patellar tendon. MATERIAL AND METHODS: twenty one patients having a chronic anterior instability sustained a modified Marshall-Mac Intosh procedure, while 15 having a subacute torn ACL had an ACL reconstruction using a free bone-patellar tendon-bone graft. The patients were retrospectively reviewed with a 1.8 year average follow-up (1-3 years). The clinical result was evaluated through the comparative range of motion, the residual laxity as measured with the KT 1000 arthrometer, and the pivot shift test. The roentgenographic analysis was performed from AP and ML views, made first on one-leg standing with the knee at 30 degrees of flexion, and then in "zero" extension with active quadriceps contraction. Lines were drawn to visualise the location of the tibial and femoral tunnels in relation to the tibial plateaus and the roof of the intercondylar notch represented by the Blumensaat line. The analysis of the AP IRM views of the graft allowed to discriminate between homogeneous and heterogeneous graft signals. RESULTS: on lateral roentgenograms of normal knees it was found that the Blumensaat line crossed the surface of the medial tibial plateau at its anterior third, at 30 +/- 9 per cent (20-40 per cent range), demonstrating the variability of the intercondylar roof inclination. The range of motion was normal in 22 patients (group 1), 8 patients had a flexion deficit (group II), and 6 exhibited an extension deficit (group III). The residual laxity was similar in each group (p > 0.05). When comparing group III to group I, patients from group III had a tibial tunnel significantly more anterior with regard to the Blumensaat line (p < 0.02). In group III, all patients exhibited an heterogeneous MRI graft signal (p < 0.05), and the angle between the intraarticular part of the graft and the tibial tunnel was higher (p < 0.001). These findings were not observed in group II where the location only of the femoral tunnel seemed to influence the flexion deficit (p > 0.05). DISCUSSION AND CONCLUSION: this study demonstrated that the location of the tibial tunnel with regard to the roof of the intercondylar notch, when the knee is in "zero" extension, was the most relevant parameter controlling the extension deficit resulting from a graft impingement. No relation was found between the tibial tunnel location with regard to the tibial plateaus and the mobility deficit. Graft impingement also was always associated with an heterogenous graft MRI signal. CLINICAL RELEVANCE: when reconstructing the ACL care must be taken when inserting the K-wire aimed to guide the tibial drill, to obtain a proper position with regard to the roof of the intercondylar notch. The K-wire location must be checked in "zero" extension. Intra-operative X-rays may help.

Anterior Cruciate Ligament↗

Alumina-alumina hip replacement in patients younger than 50 years old.

From April 1977 to December 1990, 131 total hip arthroplasties were performed on 113 patients younger than 50 years of age (median, 41 years); 64 were men and 49 women. The majority were active people. Sixty-six hips had no previous operations, and 33 had at least one previous arthroplasty. The femoral component was a cemented collared titanium alloy stem, and alumina socket was cemented for 99 hips and press-fit for 32. The mean follow-up period was five years, with 32 hips followed for more than ten years. Revision arthroplasty was considered as a failure. Survivorship analysis depicted a 97.5% rate of survival at five years, an 89.4% rate at ten years, and an 86.2% at 11 years. Nine revisions were performed: one experienced a femoral head rupture after three years, one had bipolar loosening, one experienced femoral cystic formation, and six were revised for acetabular cup loosening, all from the cemented group. Two revisions occurred on the same patient. No stem revision was necessary before ten years. Only one of these revisions was required in patients aged 40 or younger (64 patients). Alumina-alumina friction is an extremely interesting phenomenon in young patients, and could be related to the low wear debris production.

Adult↗

Ten-year survivorship of cemented ceramic-ceramic total hip prosthesis.

In the first 187 consecutive alumina-alumina combination hip arthroplasties performed from 1977 to 1979, both components were cemented with conventional techniques. At ten-year follow-up evaluation, 87 patients were reviewed or interviewed by telephone, 37 were dead, 39 were lost to follow-up evaluation, and 24 failures were reoperated on before the end of ten years. The major cause of failure was aseptic loosening of the acetabular component (15 failures). Fracture of the socket and of the femoral head occurred in five patients in this series. However, these complications were not seen with components manufactured after 1979. At the end of ten years, survivorship analysis depicted a 82.59% survival rate when reoperation was considered as failure and a 88.57% rate when reoperation for aseptic loosening was considered as failure. The femoral component had a 99.16% survival rate and the acetabular component had an 88.57% survival rate when reoperation for aseptic loosening was considered as failure. Age, appearance of a two- or three-zone demarcation at the intermediate follow-up evaluation, and outer diameter of the acetabular component were the major parameters influencing the results. Better results observed in the population younger than 50 years of age may be related to the small amount of wear debris produced by the alumina-alumina combination. This combination in hip prosthesis is secure, but should be implanted in young and active patients; the outer diameter of the acetabular component must be at least 50 mm. The major problem that remains is the socket's fixation. It could be improved by a design modification, by choosing another mode of fixation, or both.

Aluminum Oxide↗

[Conflict between psoas and total hip prosthesis].

This conflict leads to a chronic irritation of the psoas by the antero-medial part of the cup, but it has been poorly described in the past. A study of six patients suffering from this trauma, and who were re-operated revealed that the muscle was worn thin in front of the prominent cup. In the case of 4 of the 6 patients pain had started to occur shortly after total hip replacement. The following symptoms were noted among all 6 patients: pain was suffered during flexion--extension movements--walking up stairs--arising from a chair. Pressure on the medial part of the groin was painful, especially during active elevation of the lower limb. Passive mobility was normal and painless. Psoas bursitis was observed in three cases. The main cause of this conflict is the protrusion of the cup beyond the antero-medial edge of the acetabulum; this protrusion may be either due to a bone graft or a bit of cement, but most often an acetabular insufficiency (congenital dysplasia) favors the formation of this anterior overhang. The spiral cup screwed into the bone can be especially aggressive when it protrudes. Treatment includes the resection of the overhang, but post-operative results will be uncertain unless the resection is really complete. In the case of 4 patients the results of such an intervention were only mild to poor. This problem can be avoided by proper care and preventive measures in the original replacement avoiding all projections beyond the anterior edge of the acetabulum--cup, bone graft, cement, especially if dysplasic.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗

[The influence of the elasticity module of the femoral shaft and neck of a total hip prosthesis on the distribution of stress in the femur ].

Experiments have shown that stress shielding resulting from implantation of a prosthesis is related to the stiffness of the implant. Stiffness depends on the Young's modulus of the material used and the design of the implant. Most published studies have not attempted to define the relative importance of these two components. We have studied the influence of the elastic modulus only in an experiment using implants of a uniform design. Strain gauges were attached to the calcar in five femurs, three of which also had gauges placed on their medial, lateral and anterior aspects. Surface strain was measured in the intact femur and after implantation of cemented prostheses of the same design but manufactured with or without a collar in stainless steel or titanium alloy. The highest level of calcar strain was recorded with the titanium alloy prosthesis, and the presence of a collar appeared to increase the stress transfer of bone. This effect on stiffness was statistically significant, but was limited to the proximal part of the upper femur. It was not significant in the sub-trochanteric area, due to individual variations in bone geometry and cortical thickness. These results indicate that stress shielding can be directly related to the Young's modulus of the material used, independent of the design of the prosthesis.

Biomechanical Phenomena↗

Alumina-on-alumina hip replacement. Results and survivorship in young patients.

Total hip replacement using an alumina head and socket and a titanium alloy stem is evaluated in a series of patients under 50 years of age. Between April 1977 and December 1986, 86 such replacements were performed in 75 patients, but mainly because patients had difficulty travelling from Africa, only 71 hips were followed up adequately; of these, 56 were primary procedures and 15 revisions. Survivorship analysis showed that 98% of the prostheses were retained for 10 years. On clinical and radiological examination 51 of the 71 hips were stable and acceptable, 15 had radiological changes on the acetabular side, and one on the femoral side; four other cases had clinical and radiological changes suggesting impending failure, possibly because fixation of the socket was inadequate. There were no differences between the results of the primary procedures and those of revisions. In these young patients, the results seem better with alumina-on-alumina hips than with other varieties, possibly because of their remarkably low wear.

Adolescent↗

[Knee prosthesis in 1990. Apropos of a 15 years' experience].

Knee prostheses have been greatly refined over the past ten years. A range of prostheses with various designs are currently used. On the basis of their 15-year experience, the authors assess the role of the various prostheses. Among partial prostheses, the femoropatellar prosthesed have a restricted place and are reserved for isolate degenerative diseases of the femoropatellar joint without femorotibial involvement: 34 such prostheses have been used by the authors and the department of professor J.H. Aubriot in Caen. About 75% of the results are satisfactory, with a follow-up in time of more than 8 years in 6 of these cases. Single-compartment prostheses are used in degenerative disease on an angular deviation, condylar necrosis or post-traumatic lesions, as far as one compartment only is affected. The authors have inserted 115 "Lotus" uni-compartment prostheses at Saint-Louis hospital. 75.6% of these have very good or good results maintained in time, as 72% of the 32 prostheses still produce satisfactory results after 5 years or more. The greatest progress was made above all for total prostheses replacing all the compartments of the knee. Hinge prostheses now have only rare indications as first-intention prostheses due to the immediate vital risks and to the high percentage of suppuration and long-term loosening. Sliding prostheses have taken an increasingly dominant place. The authors used Insall's total condylar prostheses, which do not preserve the posterior cruciate ligament, until 1983. 45 prostheses were followed up for 1 to 10 years, showing 71% of very good or good results.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗