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Biomedical subjects

J Woźniak

Publications and source records attributed to J Woźniak.

At least 19 recordsLinked to original sources
PubMed1992

Erythro-toxicity of dichlorvos and possibility of its modification in vitro.

The purpose of this study was to investigate the in vitro effects of dichlorvos (organophosphorous pesticide) on the biological value of erythrocytes; an in vitro test of erythrocyte protection against DDVP effects was also included. A significant decrease of glutathione level with concomitant increase of methemoglobin and denatured hemoglobin levels, as well as a rise of Heinz body number were observed after 24 h following the treatment with dichlorvos (100 microM). Preincubation of erythrocytes with glutathione prevented the toxic effects of the pesticide with the maintenance of both glutathione and methemoglobin at a control level.

Cells, Cultured↗
PubMed1991

[Micromethod of determining the caloric value of food using chromic acid].

Rozental's method using chromic acid for the determination of the caloric value of meals has failed to find practical application, on account of applying faulty amounts of the oxidizing reagents and of the tested sample, as well as large volumes of liquids and reaction solutions. In this connection, we thoroughly verified this method, introducing another value of the correction coefficient. By changing the proportions of the reaction components, we developed a modified method referred to as micromethod for caloric value determination using chromic acid. Application of minimal amounts of reagents and tested sample allowed for analysing food samples with caloric value up to 200 kcal/100 g as well as for cutting down the duration of the analysis.

Calorimetry↗
PubMed1990

The effect of gamma-hexachlorocyclohexane (lindane) on blood cells, kidney and liver tissues in rabbits.

The effect of intragastric administration of gamma-hexachlorocyclohexane (lindane) on peripheral blood cells, kidney and liver was studied in rabbits. White blood cells were found to be most affected by lindane, as was shown by the reduced phagocytic activity of neutrophils and the increased number of lymphocytes with inactive nucleoli. The changes in the characteristics of erythrocyte cell membranes depended on the length of time lindane was administered and on its withdrawal. Histological examination of the liver and kidney showed focal degeneration of tissue and cell structure.

Animals↗