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Biomedical subjects

J Wolfson

Publications and source records attributed to J Wolfson.

At least 19 recordsLinked to original sources
PubMed1990

Complementary use of Doppler sonography and delayed right lateral scintigraphy for the diagnosis of choledochal cysts.

Both sonography and hepatobiliary scintigraphy can help to demonstrate a choledochal cyst. Our case further demonstrates that Doppler sonography and right lateral or oblique scintigraphic views can be used to differentiate more completely this entity from other infantile cholestatic syndromes. These additional maneuvers may be particularly advantageous in the affected infant under a year old in whom a confusing clinical picture may obscure the correct diagnosis.

Choledochal Cyst↗
PubMed1988

Information processing in seven-month-old infants as a function of risk status.

7-month-old full-terms and high-risk preterms (less than 1,500 grams at birth) were compared on problems of visual recognition memory and tactual-to-visual cross-modal transfer. On the visual problems, preterm infants showed significantly less differential attentiveness to novelty than full-terms. They also required longer exposure times during visual familiarization, primarily because of longer pauses between fixations. Preterms and full-terms exhibited different patterns of looking, as indicated by the duration of fixation and the frequency in shifts of gaze. On the cross-modal problems, preterms and full-terms both exhibited similar and significant preferences for familiar rather than novel stimuli, a direction of preference which suggests that these problems were relatively difficult for both groups. For the preterms, novelty and exposure-time scores were found to be related to several medical risk factors. Novelty preferences were compromised in preterms who had suffered RDS postnatally, particularly those who had required prolonged mechanical ventilation. In general, high-risk preterms exhibited deficits in visual recognition memory and in the ability to recruit, sustain, and shift attention.

Attention↗
PubMed1982

Effects of cost-sharing on users of a state's health service program.

This study analyzed some of the effects of the introduction of cost-sharing on users of the state's health service program. The study population had previously received services at no charge and consisted of people with provider-determined medical need, and included, but was not limited to people in financial need. The study sample was selected from 3 years of program service records (1977-1980). Sampling was random and stratified by key variables. Time-series analysis as well as pre/post-policy comparisons were employed. Analysis of changes in the distributions of service user characteristics and in services provided indicated that use of services was not affected adversely and that lower-income, medically needy people were not deterred from using services following the introduction of cost-sharing. Limitations to the study are reviewed, and implications of using cost-sharing in programs such as Medicaid are considered.

Adolescent↗
PubMed1980

Mycoplasma infection in the immunosuppressed leukemic patient.

A case of severe Mycoplasma sp pneumonia possibly potentiated by methotrexate occurred in a 7-year-old child with leukemia in remission. The case typifies the diagnostic dilemma that frequently occurs in the immunosuppressed host, namely an extensive bilateral pulmonary opacification that can have many causes.

Child↗
PubMed1973

The amplification of ribosomal RNA genes involves a rolling circle intermediate.

During the development of Xenopus oocytes there is a special DNA synthesis that leads to a thousandfold amplification of the genes that code for ribosomal RNA. We have used the electron microscope to study this process. Our primary observation is the presence of ribosomal DNA in rolling-circle intermediates at the time of amplification. We believe that these intermediates are involved in the amplification process, and as such offer the first example of the involvement of a rolling circle in the replication of eukaryotic DNA.

Animals↗