Transient large upright T-waves during electroconvulsive therapy.
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Biomedical subjects
Publications and source records attributed to J Youngberg.
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The Conchatherm III is a servo-controlled, easily assembled heated humidifier. We studied its effectiveness in preventing intraoperative fall in temperature in both pediatric and adult surgical patients. Despite operating room temperatures lower than 69.8 F (21 C), rectal temperature was well maintained at normal in both adults and children. Normal esophageal temperature was well maintained only in adults under these conditions. Skin temperatures showed no statistically or clinically significant difference among the four groups.
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The effects of indomethacin on A/J mice were investigated. The non-steroidal antiinflammatory drug (NSAID) indomethacin reduced significantly the number of lung adenomas 3, 4 or 8 months after urethane injection by 28, 30 and 29% respectively. The density of apoptotic cell bodies increased 2.9-fold in the lung adenomas of A/J mice treated with indomethacin. By immunocytochemistry, COX-2 immunoreactivity was present in the cytosol of lung adenomas, and in epithelial cells lining the bronchioli and bronchus as well as type 2 alveolar cells. COX-1 immunostaining was similar to that of COX-2 in the lungs of urethane-injected mice treated with or without indomethacin. By RT-PCR, COX-1 and COX-2 PCR products were present in mouse lung adenomas, alveoli and bronchioli. These results suggest that indomethacin may inhibit COX-1 and COX-2 in the A/J mouse lung resulting in reduced adenoma formation.