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Biomedical subjects

J Z Kaplan

Publications and source records attributed to J Z Kaplan.

6 recordsLinked to original sources

Immediate health effects of an urban wildfire.

To document the immediate health effects of the urban wildfire that swept through parts of Alameda County, California, on October 20 and 21, 1991, we conducted a retrospective review of emergency department and coroner's records. Nine hospitals (6 local and 3 outlying) were surveyed for the week beginning October 20, 1991. Coroner's reports were reviewed for 25 identified fire-related deaths. A total of 241 fire-related emergency encounters, including 44 inpatient admissions, were recorded for 227 persons. Nearly a fourth of emergency department patients were seen for work-related injuries, more than half of which occurred among professional firefighters. Smoke-related disorders constituted more than half of all emergency department cases; of these, 61% had documented bronchospasm. Major trauma and burns contributed 1% and 4% of principal diagnoses, respectively; these were exceeded in number by corneal abrasions (13%), other medical problems (8%), and minor trauma (7%), among other diagnoses. All coroner's cases involved extensive burns, many with documented smoke inhalation injury. While the Oakland-Berkeley fire storm resulted in a high case-fatality ratio among major burn cases (25/31), those who survived the initial fire storm did well clinically. Among emergency department patients, medical (particularly smoke-related) disorders outnumbered traumatic presentations by a ratio of more than 2 to 1.

Adolescent↗

Acceleration of wound healing by a live yeast cell derivative.

Acceleration of the normal rate of burn wound healing would serve to decrease the morbidity and possibly the mortality of burn victims. A live yeast cell derivative (LYCD) has previously been reported to stimulate wound epithelialization and this study was designed to evaluate that hypothesis. Twenty-six human skin graft donor sites in nine patients were compared in a double-blind, randomized, single-center inpatient study. Thin donor sites were used as a model for superficial wound healing. Statistically significant earlier angiogenesis and epithelialization occurred in donor sites treated with LYCD ointment as compared with donor sites in the same patients treated simultaneously with ointment base. Stinging pain was noted by seven patients, but in all cases the pain was mild and required no analgesia.

Adult↗