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Biomedical subjects

J Zajaczkowska

Publications and source records attributed to J Zajaczkowska.

At least 19 recordsLinked to original sources

[The role of bronchoscopy and bronchoalveolar lavage in diagnosis of pulmonary tuberculosis in AIDS].

Bronchoscopy was carried out in 32 HIV seropositive patients, most with AIDS during the period between January 1992 and August 1993. In 14 patients tuberculosis was diagnosed, in 13 it was bacteriologically confirmed. The mean age of the examined patients was 35.5 years (range 22-49 years). In 50% of the BAL samples bacterioscopy was positive. Bacteriological examination of the sputum and BAL fluid (bacterioscopy and culture) produced a confirmation of tuberculosis in 99.9% of the cases.

AIDS-Related Opportunistic Infections

[AIDS and tuberculosis].

From Jan. 1, 1989, through July, 1, 1991, 193 patients with HIV infection were treated at the Department of Acquired Immunodeficiency, Infectious diseases Hospital in Warsaw. Tuberculosis was diagnosed in 11 (5.7%) cases; in three cases diagnosis was first established post mortem. In eight cases tuberculosis was diagnosed clinically and confirm by microbiologic or histologic examinations. Antituberculous chemotherapy was successful in five cases (early results). All 11 patients had other concomitant infections or neoplasms. Six of 11 patients died, of them 3 with misdiagnosis of tuberculosis prior to death. The problem of HIV infection and tuberculosis and its impact on epidemiology of tuberculosis is discussed.

Acquired Immunodeficiency Syndrome

[Preliminary evaluation of the diagnostic usefulness of bronchoalveolar lavage (BAL) in selected cases of interstitial lung diseases].

Diagnostic usefulness of BAL was assessed in 25 selected cases of interstitial lung diseases. There were 14 cases of allergic alveolitis, 6 cases of idiopathic pulmonary fibrosis and one case each of sarcoidosis, lymphangiomyomatosis, granulomotosis bronchocentrica, lymphogranulomatosis maligna, alveolitis of unknown etiology. BAL was assessed diagnostically usefull in 77% of the cases. More helpful was medical history which proved to be useful in all cases, and pulmonary function tests which were helpful in 84%. Lung biopsy was diagnostic in 66.6% of the cases, TBLB in 36.5%, while open lung biopsy carried out in 6 patients was diagnostic in 100%. Bronchoalveolar lavage is a useful element of diagnostic evaluation in patients with interstitial lung disorders, it is a safe method and well tolerated by the patients.

Adult

[Further studies on the occurrence of mycoses in the bronchial stump and bronchial anastomosis or trachea].

In the years 1980-1985 sutures were removed endoscopically from stumps and anastomoses in 52 patients operated in the years 1969-1985. The total number of bronchoscopies was 154, in 88 protruding threads into the airway lumen were removed. Interval between removal of first suture and date of surgery ranged from 0.5 to 192 months. Mycotic infection was diagnosed in 5 cases (9.6%). The causative agents being Aspergillus fumigatus and Candida albicans. In all cases removal of protruding threads lead to a complete cure. It was found that incidence of such mycotic infections decreased from 20.2% observed during the years 1962-1979 to 9.6% in the years 1980-1985.

Adult

Transbronchial lung biopsy in diffuse pulmonary disease.

Transbronchial lung biopsy (TBB) was performed via the fibreoptic bronchoscope in 243 patients with bilateral diffuse pulmonary shadows. Histological diagnosis was established in 54.4%. The highest diagnostic yield was obtained in sarcoidosis (73.7%), the lowest in the group of cases denoted "fibrosis" (38.7%). Statistical analysis did not allow to establish the optimal number to be taken at a single procedure but it showed that the probability of obtaining the diagnosis in sarcoidosis was 2.6% at the first specimen taken, while in fibrosis it was nul at the first and at the second specimen. The overall diagnostic yield was related to the number of cases of sarcoidosis in the material examined. Among 138 cases examined in 1984-1986, in 80 the initial biopsy failed to establish the diagnosis; in 28 of them the procedure was repeated, and positive results were obtained in 60.7% thus increasing significantly diagnostic yield. An attempt to correlate the TBB findings with bronchoalveolar lavage (BAL) showed that BAL was a valuable diagnostic factor. No major complications occurred.

Adolescent

Diagnostic value of bronchial catheterization in bronchial carcinoma.

Bronchial catheterization is a valuable contribution to bronchoscopy. It increased positive results by 28.1% in 1971-1976, and by 32.2% in 1977-1979. The results of catheterization correlated with hose of resection specimens. No false positive results were observed. With better experience of the physicians and the better equipment better results were obtained in the last three years. The examinations were performed under topical anesthesia.

Adenocarcinoma