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J de Mouzon

Publications and source records attributed to J de Mouzon.

47 records · Page 3Linked to original sources
PubMed1980

[Antenatal assessment of gestational age (author's transl)].

Antenatal assessment of fetal gestational age has been performed by amniotic fluid analyses and ultrasonography. Average estimation of amniotic fluid creatinine and glucose, Clements' test and biparietal diameter measurements produce an accurate assessment of gestational age in 80 % of normal or pathological cases. When amniocentesis is performed to estimate fetal lung maturity, this assessment of gestational age can improve obstetrical care.

Amniocentesis↗
PubMed1978

[The value of measuring blood pH in fetal monitoring during labour (author's transl)].

The authors present a series of methodological studies carried out to assess the value of the place of measuring fetal blood pH in monitoring in labour. Comparisons of the measures of pH, pCO2, pO2 and lowering of the base were carried out on the scalp in the 3 minutes which preceded the birth and in the umbilical vessels at birth. Comparing the three modes of taking blood in the mother, intra-arterially and from the capillaries with and without local vasodilatation was carried out. The limits of the values were defined both for the fetus and the mother of the parameters of pH, pCO2, pO2 and base deficit in 100 normal deliveries. A study was carried out of their correlations with the Apgar score at 1 minute and with the arterial pH. A comparison of the two series of measurements was carried out on the vessels of the cord--arterial and venous. The results confirm the value of measuring pH for diagnosing the state of the infant during labour.

Acid-Base Equilibrium↗
PubMedDate not supplied

[Ethnic variation of the duration of gestation].

This study compares the durations of gestation of 6,885 West Indian women who delivered in Fort-de-France, with 11,818 Metropolitan, 257 West Indian and 110 African women whose deliveries took place in Clamart (France). Mean duration of pregnancy was 4/10 of a week shorter: i.e. 3 days, for West Indians. There was no difference between West Indians giving birth in Fort-de-France as opposed to those giving birth in Clamart. Duration of pregnancy was shortest for Africans as compared with West Indians and Metropolitans. These differences were statistically significant. At Clamart, despite standardization allowing for maternal ages, parity and socio-economic status, mean differences and their statistical significance remained.

Africa↗
PubMedDate not supplied

[Cancer of the ovary and the treatment of infertility. Analysis of the article by Whittemore et al].

Whittemore and al. recently published a general paper concerning the risk factors of ovarian cancer, combining the data from 12 epidemiological studies realised from 1979 to 1988. Three of these studies allowed to analyze the role of infertility treatments which were associated to an increased risk (odds ratio = 2.8), specially in nulligravid women (OR = 27.0). However potential bias could not be rejected, and information on drugs was too scanty, so that no definite conclusion could be drawn, even if the results were in accordance with the main physicopathogenical theories. In conclusion, it appears necessary to undertake a large epidemiological study, and, in the same time, even if patients must be reassured, to recommend attention to the doctors when prescribing infertility treatments.

Case-Control Studies↗
PubMedDate not supplied

[Paternal age and fertility].

Variations of the male partner fertility according to his age are difficult to study, because of bias represented by some decrease of both sexual activity and fecundity of the female partner beyond 35 years old. The few studies which are available show that sperm concentration as percentage of normal forms, are stable with age. The percentage of motility is the only parameter which decreases systematically with age according to all studies. Nevertheless, sperm fertilizing capacity does not seem to be decreased. FIVNAT data allow to analyse almost 30,000 IVF cycles for tubal sterility; they confirm the absence of an important alteration of semen characteristics with age. Despite a significant decrease--even moderate--of the mean fertilization rates, the pregnancy rates remain roughly constant for a given range of maternal age.

Adult↗
PubMedDate not supplied

[Seasonal variation in sperm characteristics].

In all species, seasonal patterns in fertility are observed. In humans, seasonal variations of pregnancies are observed in spontaneous reproduction or in IVF. The most important factor seems to be sperm values and specially the morphology. Our study, on 188,075 cases (FIVNAT 1987-1995) shows significant variations of semen characteristics: we observe, in August, an improvement of sperm morphology.

Female↗
PubMedDate not supplied

[1997 FIVNAT general balance].

In 1997, the French National Register on in vitro fertilization, FIVNAT, has collected information on 3,854 initiated cycles and 36,583 oocyte recoveries, from which 61.2% were conventional IVF cycles and 38.6% were ICSI. For conventional IVF, the percentage of infertilities of tubal origin was 49.7%, whereas 45% of the recoveries involved a male factor. The stimulation regimen involved a GnRH in 95% of the cases mostly with a long blockage period (82.6%) which was associated to the highest pregnancy rate. The mean number of transferred embryos significantly decreased to 2.50 +/- 0.95 per transfer. Only 9.2% of the transfers involved more than 3 embryos, and were associated to a relatively poor pregnancy rate, confirming that they were preferently realised in couples with poor chances of pregnancy. Finally, the pregnancy rate per recovery (20.5%) and per transfer (26.0%) remained at the same level as in 1996.

Adult↗
PubMedDate not supplied

FIVNAT. Influence of attempt rank in in vitro fertilization.

The French national register on in vitro fertilization (IVF) FIVNAT, which has collected most of the oocyte pick-ups realised in France since 1986 has allowed us to build a cohort of 35,714 couples, of which the first recovery took place between 1990 and 1994 and followed up to a pregnancy or to the 31st of december, 1996. The per recovery clinical pregnancy rate decreased from 20.2% on the first attempt to 17.4% on the second, and to less than 13% after the sixth. This evolution existed whatever the women's age class or the infertility diagnosis. The women's age remained the most important factor, since the cumulative pregnancy rate decreased from 60% for women aged less than 35 years to 17% for those aged more than 41 years. Among the indications, male infertility using spouse's semen had the poorest prognosis, especially for women aged more than 41 years (9.6%) whereas male infertility using donor's semen among women aged less than 35 years was associated to the best results (68%). It must be noticed than a high percentage of unpregnant women did not come again for a further recovery (40% to 50%). Then, the crude cumulative birth rate (24.4%) was far below the theoretical cumulative one(54.2%).

Age Factors↗
PubMedDate not supplied

[Ovulation stimulation].

In 1997, 2 new recombinant FSH were available. The analysis of the first 11,000 attempts IVF and ICSI received by FIVNAT for 1997 shows that recombinant FSH was used in about 20% of cases. Pregnancy rates were similar with urinary and recombinant FSH but the number of ampoulles was significantly lower with recombinant FSH.

Female↗