PubMed Health⌕ Search

Biomedical subjects

J van de Walle

Publications and source records attributed to J van de Walle.

6 recordsLinked to original sources

Some considerations on the pharmacological treatment of pain.

Drug treatment of pain is largely based on clinical experience. Some aspects of the analgesic therapy with drugs are discussed on the hand of data, selected from the scientific literature, or obtained by own experimental work done in the pain clinic of Leuven. The choice of the analgesic compound and some valuable drug combinations are reviewed. Possibilities for the evaluation of the analgesic efficacy, other as the simple but most important verbal report, are mentioned. Problems, associated with a prolonged analgesic drug therapy, are discussed. (Acta anaesth. belg., 1981, 32, 13-20).

Analgesics↗

Total I.V. anesthesia using a continuous etomidate infusion.

Total I.V. anesthesia was given to 20 patients using an Etomidate continuous infusion to maintain sleep, combined to Fentanyl analgesia, Droperidol, Pancuronium for muscular relaxation and artificial ventilation with an oxygen-air mixture. All these patients were carefully observed during and for several hours after the anesthesia and the results noted. With the Fentanyl dosages used in this technique, peroperative analgesia was frequently insufficient. More Fentanyl would probably be needed with the inherent dangers of prolonged postoperative depression.

Adult↗

Clinical evaluation of a new oral contraceptive, 'Pregnon'.

'Pregnon', a new oral contraceptive containing 1 mg. lynestrenol and 0.05 mg. ethinyl oestradiol, was administered cyclically to 639 women of fertile age over a total of 9,159 cycles. There were no pregnancies. In most cases the withdrawal bleeding resembled normal menstruation. The incidence of metrorrhagia was relatively low and when it did occur it was usually confined to the early treatment cycles and was of very limited duration. The objective and subjective tolerance was excellent.

Adolescent↗