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Biomedical subjects

Jörg Meister

Publications and source records attributed to Jörg Meister.

6 recordsLinked to original sources

Temperature evolution on human teeth root surface after diode laser assisted endodontic treatment.

The thermal rise threshold of an 810-nm semi-conductor diode laser on the root surface when used in root canals in vitro for laser assisted root canal treatment is investigated in this study. A total of 50 human single-rooted extracted teeth were included. For this study, the canals were enlarged up to an apical size of ISO#50 file. Laser irradiation was performed with six different settings. Specimens were irradiated at 0.6-1 W output power at the distal end of the fiber and about 1-1.5 W output power in the continuous mode (CW) as two groups. In the third group, 0.6-1 W output power, 10 ms pulse length (PL) and 10 ms interval duration (ID) were selected. In three other groups 1-1.5 W output power were used with different PL and ID as following: PL 10 and ID 10 ms, PL 10 and ID 20 ms and PL 20 and ID 20 ms. The total irradiation time was from 5 to 20 s per canal with a 200 mum in diameter and 25 mm long tip. After laser treatment, the temperature changes at the outer root surface were registered by means of NiCr-Ni measuring sensors and a T 202 thermometer. The safe temperature threshold for applying this diode laser in root canal is considered as 7 degrees C increase. To avoid increasing the temperature changes at the outer root surface related to this threshold, following total irradiation times were found: 0.6-1 W output power (10 ms PL/10 ms ID): 20 s (s), 1-1.5 W output power (10 ms/10 ms and 20 ms/20 ms): 15 s, 0.6-1 W output power CW and 1-1.5 W output power (20 ms PL/10 ms ID): 10 s and 1-1.5 W output power CW: 5 s. In the first three groups, 5 s irradiation and 5 s rest period avoided a temperature increase above the threshold of 7 degrees C).

Body Temperature↗

Multireflection pumping concept for miniaturized diode-pumped solid-state lasers.

An innovative pump concept for diode-pumped, solid-state lasers is introduced as an example for an Er:YSGG laser, permitting its miniaturization. Embedded in a multireflective pump cavity, the laser crystal is simultaneously side and end pumped. Specially calculated and shaped deflecting optics distribute the coaxially input pumping light homogeneously over the lateral surface of the crystal, therefore reducing the size of the laser head, including the optical resonator, to a length of 27.5 mm and an outside diameter of 12.5 mm. The differential efficiency achieved is between 8.7% and 24%. The laser emits energy of 15.7 mJ at an absolute efficiency of 9.1% and a repetition rate of 4 Hz.

Equipment Design↗

Influence of the spatial beam profile on hard tissue ablation, part II: pulse energy and energy density distribution in simple beams.

When calculating applied flux densities in practice, the beam profile of a laser is often erroneously assumed to be homogeneous. In addition, there is usually no consistency in the choice of a suitable measuring method for determining the beam diameter. This failure to observe the inhomogeneous intensity distribution within the beam cross-section, combined with the imprecise knowledge of the beam diameter, leads to flux densities being stated that represent mean values at best. The present paper gives definitions for the flux densities of simple, radially symmetrical beam cross-sections, taking the top-hat and Gaussian profiles as examples. In connection with the inhomogeneous energy distribution in the Gaussian beam, a concept of integral and local energy density is discussed, which differs from the customary definition of the energy density as a constant. Also presented are the consequences of the mathematical concepts in terms of measurement, giving particular consideration to the case where the energy density as the measured variable matches the integral energy density. The significance of the integral and local energy density for hard-tissue ablation is described, based on the practical example of the ablation of dental hard substance. The central result is that the integral flux density is directly accessible as a measured variable, while the effect on the tissue is determined by the local flux density. If the form of the beam is known, the integral flux density can be converted into the local flux density.

Dental Enamel↗

Small-volume frequency-domain oximetry: phantom experiments and first in vivo results.

We describe a new method to determine the oxygen saturation and the total hemoglobin content of tissue in vivo absolutely at small source-detector separations (<10 mm). Phase and mean intensity of modulated laser light of various wavelengths was measured at several predetermined source-detector separations in the frequency domain. From these measured quantities, the absorption coefficient was derived using the modified time-integrated microscopic Beer-Lambert law (MBL). In addition, the interaction volume of the photons was determined using a multi-layer Monte-Carlo model of human skin. To evaluate the method, we employed homogenous solid phantoms (consisting of TiO2 particles embedded in resin) with mean scattering and absorbing properties comparable to those of human skin. Furthermore, in vivo measurements were performed in a healthy volunteer to demonstrate that the technique is applicable for the determination of the oxygen saturation and the total hemoglobin content in the skin in vivo. The proposed technique is especially suited for the on-line determination of the oxygen saturation and total hemoglobin content in applications where small applicators are required (e.g., fetal oxygen monitoring sub partu).

Algorithms↗

[Quality assurance versus regulation--the perspective of a lawyer].

In February 2003, the German Federal Ministry of Health presented a concept for establishing a German National Institute for Clinical Excellence. In sharp contrast to this concept, a closer look at other medical quality assurance activities in Germany shows that there is no area of responsibility in the German health care system where such an institution might prove useful. In Germany, the institutions of self-administration were the first to organise and promote medical quality assurance activities. The German Hospital Federation, the Association of Sickness Funds for salaried employees, the Association of Private Health Insurers, the professional organisations of German physicians and other organisations of self-administration entered into contracts pertaining to a medical quality partnership in order to create maximal benefit for all patients, i.e. to exactly address the patients' needs and treat their diseases with the best possible outcome. Such a framework of self-administration renders redundant the requirement for a German National Institute for Clinical Excellence.

Delivery of Health Care↗

Influence of the water content in dental enamel and dentin on ablation with erbium YAG and erbium YSGG lasers.

The theory of the ablation of dental hard tissue with erbium lasers is based on a process of thermomechanical interaction, which is explained by the absorption of the radiation in the water component of the tissue. The abrupt evaporation of the water is the cause of tissue fragments being blasted out of the tooth structure. The aim of this study is to examine the effect of the water contained in dental hard tissues on the efficiency of ablation. 192 specimens of both bovine dental enamel and bovine dentin are irradiated with an Er:YAG and an Er,Cr:YSGG laser. Half of the specimens are dehydrated beforehand. Irradiation is carried out in subgroups: without water spray and with water spray at flow rates of 0.8 and 3 mls. The ablated volume is determined following histological preparation. Only in dentin, and then only with irradiation with the Er:YAG laser, is the water contained in the tissue found to have a significant influence (p < 0.0001) on the ablated volume. The water content has no effect on the efficiency of laser ablation in any of the other test groups. In contrast, the externally supplied water always has a significant influence on the effectiveness of the ablation process.

Dental Cavity Preparation↗