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Biomedical subjects

Jörg Stürmer

Publications and source records attributed to Jörg Stürmer.

4 recordsLinked to original sources

Correlation between intraocular pressure, central corneal thickness, stage of glaucoma, and demographic patient data: prospective analysis of biophysical parameters in tertiary glaucoma practice populations.

PURPOSE: To determine the correlation of central corneal thickness (CCT) to Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT, PASCAL), and to glaucoma stage as assessed by cup-to-disc ratio (CDR). DESIGN: Prospective, cross-sectional tricenter observation study. PATIENTS AND METHODS: From three glaucoma specialty practices a sample of 406 independent eyes was included. After ultrasound pachymetry, intraocular pressure was measured using PASCAL and Goldmann applanation tonometry and cup-to-disc ration was reassessed. Demographic data were included in the multivariate analysis. RESULTS: Mean corneal thickness was 540 microm. African Americans and normal-tension glaucoma patients showed the lowest values (518 microm and 522 microm, respectively). These values were significantly thinner than the central corneal thickness of Caucasians (549 microm) and ocular hypertensives (564 microm). Intraocular pressure assessed by Goldmann applanation tonometry shows a significant correlation with central corneal thickness (r = 0.068, P < 0.001), whereas PASCAL is not significantly associated with central corneal thickness (r < 0.001, P = 0.997). Increased IOP is significantly correlated with large ocular pulse amplitudes (r = 0.13, P < 0.001), which is predominantly seen in ocular hypertensives. A significant negative correlation was detected between cup-to-disc ratio and central corneal thickness (r = 0.102, P < 0.001). CONCLUSION: Glaucoma patients with thin central corneal thickness are more likely to be found at an advanced stage of the disease and among those with normal-tension glaucoma and black African ancestry. Underestimation of intraocular pressure by Goldmann applanation tonometry could be one causative factor.

Adolescent↗

[Simultaneous bilateral cataract extraction--a retrospective study].

BACKGROUND: In patients with bilateral cataracts and contraindications for local anaesthesia a simultaneous bilateral cataract extraction under general anaesthesia is worth considering. PATIENTS AND METHODS: The retrospective study includes all 19 patients (aged 58 to 94 years, mean age 81.5 years) who underwent simultaneous bilateral cataract extraction at our hospital in a period of two years. While the majority of patients had bilateral phacoemulsification, five eyes of three patients underwent planned extracapsular cataract extraction. The preoperative ophthalmic and anaesthetic data and the perioperative and postoperative follow-up data are evaluated. Additionally patient satisfaction and financial aspects are investigated (coverage of the second eye surgery by health-insurance). RESULTS: In none of the 19 patients did severe complications occur. The majority of patients showed a fast visual rehabilitation with a striking improvement in their quality of life. The majority of eyes (20/38; 52.6 %) achieved a visual acuity of 20/30 or better. The analysis of financial aspects disclosed disadvantages for the hospital. CONCLUSIONS: Simultaneous bilateral cataract extraction can be considered as a safe and effective method for a selective group of patients with bilateral cataracts.

Aged↗

[Cataract surgery and the "Blue Miracle"].

BACKGROUND: Continuous circular capsulorhexis enabling safe phacoemulsification and implantation of the PC-IOL in the bag is extremely difficult to perform in the absence of red reflex. Staining of the anterior capsule with a vital dye (Vision blue(R); DORC, The Netherlands) allows easy capsulorhexis under such conditions. PATIENTS AND METHODS: Because of missing or poor red reflex Vision blue(R) was applied to allow capsulorhexis in 26 eyes of 25 patients (aged 24 - 86 years). Sixteen patients had mature cataracts, two patients had dense vitreous opacities and 8 patients had pronounced anterior subcapsular opacifications. RESULTS: Continuos circular capsulorhexis was easy to perform in 22/26 eyes after staining the anterior capsule with Vision blue(R). Due to increased intracapsular pressure two eyes developed an uncontrolled tearing of the anterior capsule towards the periphery, and in two eyes capsulotomy had to be completed with high-frequency capsulotomy or scissors. Ten of sixteen eyes with mature cataracts had extremely hard nuclei requiring extended phacoemulsification time (more than 90 seconds calculated for 100 % power). There was no rupture of the posterior capsule nor vitreous loss. All PC-IOL's (23 x Acrysof(R); Alcon; 3 x 6.5 mm PMMA) were implanted into the capsular bag. Preoperatively 19/26 eyes had visual acuity of handmotions or less, postoperatively 18/26 eyes achieved 20/30 or better visual acuity. CONCLUSIONS: In the absence of red reflex staining of the anterior capsule with Vision blue(R) allows continuous circular capsulorhexis and implantation of the PC-IOL in the bag. An extremely hard nucleus requiring extended phacoemulsification time must be expected in elderly patients with mature cataracts.

Adult↗