Biomedical subjects

J-M Giraud

Publications and source records attributed to J-M Giraud.

4 recordsLinked to original sources

PubMed2006

[Glaucoma - structural imagery: HRT, GDX, OCT].

Confocal scanning laser tomography (HRT), scanning laser polarimetry (GDx VCC), and optical coherence tomography provide quantitative data of the retinal fiber layer and optic nerve head. They have become good complementary evaluation tools for glaucomatous optic neuropathy and their results should be analyzed with clinical data. Good knowledge of the parameters they analyze and their limitations are indispensable. To monitor progression of structural involvement, the analysis programs used need to be validated with prospective clinical studies.

Glaucoma↗

PubMed2005

[Diagnostic laser in glaucoma: scanning laser polarimetry (GDx VCC) and confocal scanning laser tomography (HRT)].

Automated structural measurements of retinal nerve fibers and optic nerve head are possible with new lasers providing objective and reproductible data for analysis. Scanning laser polarimetry (GDx VCC), based on retardation of polarized light, assesses peripapillary nerve fiber layer thickness. Confocal scanning laser tomography yields precise topographic maps of the optic disc and peripapillary retina. The advantages, applications for glaucoma detection, both in a screening setting as well as for monitoring progression, limitations and pitfalls need to be well known and results should be analyzed with clinical data.

Disease Progression↗

PubMed2005

[Practical assessment. Ocular hypertension].

In cases of high intraocular pressure, the patient's hypertension must first be confirmed and its characteristics delineated with a diurnal IOP curve or at least several different measures. Central corneal thickness should be measured, since a thin cornea is a risk factor of progression toward glaucomatous neuropathy. Later, the optic nerve head and retinal nerve fibers should be tested (HRT, GDx, and OCT), to determine whether the ocular hypertension is associated with other findings, and visual field analysis should be carried out (standard automated perimetry, blue-yellow perimetry, FDT), completed by a search for associated risk factors. Therapeutic decisions will be based on this workup, keeping in mind that in the majority of cases, monitoring and information are sufficient but necessary; treatment should, however, be initiated in cases of ocular hypertension with a high risk of progression.

Humans↗

PubMed2004

[Treatment of acute angle-closure glaucoma].

Treatment of acute angle-closure glaucoma is now better adapted for each stage of the disease. The urgent necessity to lower intraocular pressure is normally achieved using medical therapy followed by laser peripheral iridotomy and sometimes by filtration surgery. Early argon laser peripheral iridoplasty is effective and safe in some cases, allowing a very early peripheral iridotomy to be performed and avoiding systemic treatment. When surgery is required, lens extraction must be considered. In all cases, IOP control and regular gonioscopic examination the 1st Year are essential to detect peripheral anterior synechiae.

Acute Disease↗