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Biomedical subjects

Jack S Shanewise

Publications and source records attributed to Jack S Shanewise.

12 recordsLinked to original sources

How to reliably detect ischemia in the intensive care unit and operating room.

Detection of myocardial ischemia in the perioperative period is important because it allows for intervention that may prevent progression of ischemia to myocardial infarction. Perioperative ischemia is also an important predictor of adverse cardiovascular outcomes. Patients should first be stratified according to their risk of having cardiovascular disease by identifying major, intermediate, and minor predictors of adverse cardiovascular outcome. Electrocardiographic (ECG) monitoring for ischemia is inexpensive and noninvasive, but may not be applicable to all patients and is not perfectly sensitive or specific. Modern operating room monitors can automate ST segment monitoring and be set to alarm if changes occur. Increases in central venous pressure and pulmonary artery pressure can be caused by myocardial ischemia, but have been shown to be very insensitive compared to ECG. Also, detection of these hemodynamic changes requires insertion of invasive monitoring devices. Transesophageal echocardiography can be used to detect myocardial ischemia by identifying changes in regional wall motion. These transesophageal echocardiography changes occur sooner and more frequently than ECG changes, but require greater knowledge and skill to properly interpret.

Catheterization, Swan-Ganz↗

Repair of mycotic aortic pseudoaneurysm with a stent graft using transesophageal echocardiography.

A 54-year-old man who underwent uneventful orthotopic heart transplantation 1 year previously had low-grade fever and dyspnea. Imaging studies revealed an ascending aortic pseudoaneurysm (AAP), which was repaired with a 5-mm polyester patch, with circulatory arrest and cardiopulmonary bypass. Intraoperative cultures of the AAP grew methicillin-resistant Staphylococcus aureus, and the pseudoaneurysm recurred after 6 weeks despite intravenously administered antibiotic therapy. A 28.5-mm x 3.3-cm Gore Excluder aortic cuff was deployed in the ascending aorta through a left axillary artery cutdown with use of combined transesophageal echocardiography and fluoroscopy. In addition, controlled hypotension and asystole were established with administration of adenosine to facilitate precise device deployment. Postoperative imaging with transesophageal echocardiography and magnetic resonance angiography revealed complete resolution of the AAP, and the patient had done well at 7-month follow-up. Treatment of a mycotic aortic pseudoaneurysm with an endoprosthesis in a patient without other treatment alternatives can be performed safely, with acceptable short-term results.

Aneurysm, False↗

The use of the SonoSite ultrasound device for intraoperative evaluation of the aorta.

OBJECTIVE: Neurologic complications remain a significant cause of morbidity and mortality in cardiac surgery. Risk factors for neurologic injuries include the presence of atheromatous disease in the aorta. Epiaortic ultrasound has been shown to be superior in detecting the extent and location of atheromatous disease. The SonoSite Corporation (Bothell, WA) has recently introduced an affordable, portable, high-resolution ultrasound device. This new device was compared with the Hewlett-Packard Sonos 5550 ultrasound device (currently manufactured by Philips, Andover, MA) to determine suitability for this purpose. DESIGN: Prospective, serial comparison of 2 devices. SETTING: University hospital. PARTICIPANTS: Fifty consecutive cardiac surgery patients. INTERVENTIONS: Intraoperative epiaortic ultrasound images were obtained using a SonoSite 180 Plus ultrasound device and a Hewlett-Packard Sonos 5500 ultrasound device. Three observers graded recorded images based on extent of atheromatous disease. MEASUREMENTS AND MAIN RESULTS: Two patients were excluded because of errors in recording images. For the 48 remaining patients, consensus (median) grades had an observed agreement of 93.6% compared with a chance agreement of 67.7%. This correlates to a kappa value of 0.80 or near-excellent agreement. CONCLUSIONS: The near-excellent agreement of the 2 devices is acceptable, thus providing a unique opportunity to expand the use of epiaortic ultrasound imaging.

Adult↗

An unusual cause of left ventricular outflow tract obstruction after mitral valve repair.

Left ventricular outflow tract (LVOT) obstruction caused by systolic anterior motion is a cause of failed mitral valve repair. Intraoperative transesophageal echocardiography has been very helpful in diagnosing problems with mitral valve repairs intraoperatively, allowing immediate correction. We report an unusual cause of LVOT obstruction attributed to prolapse of the annuloplasty ring into the LVOT. Intraoperative hemodynamics were normal, and the diagnosis would not have been made before leaving the operative suite without the transesophageal echocardiography.

Cardiac Surgical Procedures↗

Off-pump coronary surgery: how do the anesthetic considerations differ?

In recent years, there has been much interest in performing coronary artery bypass graft (CABG) surgery without the aid of cardiopulmonary bypass (CPB). Initial efforts focused on "minimally invasive" direct coronary artery bypass, wherein the left anterior descending artery is bypassed with an in situ left internal mammary artery graft through a small left anterior thoracotomy. A more widely adopted approach however, is off-pump CABG (OPCAB), in which CABG surgery is performed on one or more vessels through the usual median sternotomy approach without the aid of CPB. This article reviews the differences in the anesthetic considerations of OPCAB compared to conventional CABG using CPB.

Anesthesia↗

Intraoperative echocardiography and minimally invasive cardiac surgery.

The term minimally invasive cardiac surgery encompasses a number of different techniques, each with its own rationale, origin, and development, but all focusing on limiting the physiologic trespass of cardiac surgery on the patient. In this article, we discuss the application of intraoperative echocardiography to three types of these procedures: Offpump coronary artery bypass graft (OPCABG) surgery, valvular surgery through limited thoracic incisions, and port-access heart surgery.

Adult↗

Development and analysis of a new certifying examination in perioperative transesophageal echocardiography.

UNLABELLED: A key element in developing a process to determine knowledge and ability in applying perioperative echocardiography has included an examination. We report on the development of a certifying examination in perioperative echocardiography. In addition, we tested the hypothesis that examination performance is related to clinical experience in echocardiography. Since 1995, more than 1200 participants have taken the examination, and more than 70% have passed. Overall examination performance was related positively to longer than 3 mo of training (or equivalent) in echocardiography and performance and interpretation of at least six examinations a week. We concluded that the certifying examination in perioperative echocardiography is a valid tool to help determine individual knowledge in perioperative echocardiography application. IMPLICATIONS: This report describes the process involved in developing the certifying transesophageal echocardiography examination and identifies correlates with examination performance.

Anesthesiology↗