PubMed Health⌕ Search

Biomedical subjects

Jacob Feldman

Publications and source records attributed to Jacob Feldman.

14 recordsLinked to original sources

Determination of visual figure and ground in dynamically deforming shapes.

Figure/ground assignment - determining which part of the visual image is foreground and which background - is a critical step in early visual analysis, upon which much later processing depends. Previous research on the assignment of figure and ground to opposing sides of a contour has almost exclusively involved static geometric factors - such as convexity, symmetry, and size - in non-moving images. Here, we introduce a new class of cue to figural assignment based on the motion of dynamically deforming contours. Subjects viewing an animated, deforming shape tended to assign figure and ground so that articulating curvature extrema - i.e., "hinging" vertices - had negative (concave) contour curvature. This articulating-concavity bias is present when all known static cues to figure/ground are absent or neutral in each of the individual frames of the animation, and even seems to override a number of well-known static cues when they are in opposition to the motion cue. We propose that the phenomenon reflects the visual system's inbuilt expectations about the way shapes will deform - specifically, that deformations tend to involve rigid parts articulating at concavities.

Cues↗

Individuation of visual objects over time.

How does an observer decide that a particular object viewed at one time is actually the same object as one viewed at a different time? We explored this question using an experimental task in which an observer views two objects as they simultaneously approach an occluder, disappear behind the occluder, and re-emerge from behind the occluder, having switched paths. In this situation the observer either sees both objects continue straight behind the occluder (called "streaming") or sees them collide with each other and switch directions ("bouncing"). This task has been studied in the literature on motion perception, where interest has centered on manipulating spatiotemporal aspects of the motion paths (e.g. velocity, acceleration). Here we instead focus on featural properties (size, luminance, and shape) of the objects. We studied the way degrees and types of featural dissimilarity between the two objects influence the percept of bouncing vs. streaming. When there is no featural difference, the preference for straight motion paths dominates, and streaming is usually seen. But when featural differences increase, the preponderance of bounce responses increases. That is, subjects prefer the motion trajectory in which each continuously existing individual object trajectory contains minimal featural change. Under this model, the data reveal in detail exactly what magnitudes of each type of featural change subjects implicitly regard as reasonably consistent with a continuously existing object. This suggests a simple mathematical definition of "individual object:" an object is a path through feature-trajectory space that minimizes feature change, or, more succinctly, an object is a geodesic in Mahalanobis feature space.

Bayes Theorem↗

What change detection tells us about the visual representation of shape.

Many recent findings suggest that human observers are surprisingly "blind" to changes in visual displays, failing to notice when substantial scene elements are added, subtracted, or altered in successive presentations of the scene. But observers are far more sensitive to certain visual changes than others, and we suggest that which types of changes enjoy differential sensitivity can reveal a great deal about the underlying visual representations. In this study, we investigate how the human visual system represents the shape of objects by demonstrating a previously unknown influence on detection of changes in shape: the sign of contour curvature. We show that subjects are substantially more sensitive to changes in concave regions of a shape's contour than to changes in convex regions, even when these changes do not alter the number or location of parts. Further, we show that this effect is modulated by figure-ground assignment, so that changes to the same physical contour are more or less detectable, depending on the contour's perceived figural status, which determines whether the change falls in a concave or convex region. The results demonstrate a heightened sensitivity for changes at concavities that is not reducible to a sensitivity to changes in gross part structure.

Form Perception↗

Rehabilitation of West Nile Fever (WNF) encephalitis in elderly.

In the summer of 2000, an outbreak of WNF affected Israel. Thirty-two elderly patients were admitted to Meir Hospital. WNF encephalitis may result in residual functional damage. However, little information is available regarding the rehabilitation of these patients. Five elderly subjects with residual functional damage were referred to geriatric rehabilitation. Patients were treated with the routine program for neurological rehabilitation after stroke, including daily physiotherapy and occupational therapy. All five were over 77 years and independent before admission. The mean FIM score on admission was 71 (S.D. = +/-8.5) and increased to 102 (S.D. = +/-14) on discharge. MMSE on admission was 60% (S.D. = +/-7.5%), and increased to over 90% on discharge in all of the patients. Clock Completion Test was normal in four on admission, and improved to normal in the fifth patient on discharge. WNF encephalitis may present with functional and intellectual impairment in the elderly. Routine geriatric neurological rehabilitation may benefit those with prolonged functional decline.

Aged↗

Information along contours and object boundaries.

F. Attneave (1954) famously suggested that information along visual contours is concentrated in regions of high magnitude of curvature, rather than being distributed uniformly along the contour. Here the authors give a formal derivation of this claim, yielding an exact expression for information, in C. Shannon's (1948) sense, as a function of contour curvature. Moreover, they extend Attneave's claim to incorporate the role of sign of curvature, not just magnitude of curvature. In particular, the authors show that for closed contours, such as object boundaries, segments of negative curvature (i.e., concave segments) literally carry greater information than do corresponding regions of positive curvature (i.e., convex segments). The psychological validity of this informational analysis is supported by a host of empirical findings demonstrating the asymmetric way in which the visual system treats regions of positive and negative curvature.

Humans↗

How surprising is a simple pattern? Quantifying "Eureka!".

Simple patterns are compelling. When all the observed facts fit into a simple theory or "story," we are intuitively convinced that the pattern must be real rather than random. But how surprising is a simple pattern, really? That is, given a pattern of featural data, such as the properties of a set of objects, how unlikely would the pattern be if they were actually generated at random? In conventional statistics dealing with patterns of numbers, this type of question would be answered by reference to a null distribution such as the t distribution. This paper gives the analogous answer in the realm of concept learning, that is, the formation of generalizations from patterns of featural data. Using a formal but psychologically valid definition of complexity, I derive and exhibit the distribution of subjective complexity under the hypothesis of no pattern. This leads directly to a number of applications, including a statistical test indicating whether an observed pattern is sufficiently simple that it is not likely to have been an accident: literally, the "significance of simplicity."

Bayes Theorem↗

A comparative study of the syndrome of inappropriate antidiuretic hormone secretion in community-dwelling patients and nursing home residents.

BACKGROUND AND AIMS: Limited data exist about the clinical characteristics of the syndrome of inappropriate antidiuretic hormone secretion (SIADHS) in hospitalized elderly. Moreover, there may be differences regarding this syndrome between populations, depending on the referral source to hospitals. The objectives of the study were to determine the etiology, clinical characteristics and hospital outcome in a sample of elderly hospitalized patients with SIADHS, and to compare community-dwelling patients (CDP) with nursing home residents (NHR). METHODS: This retrospective chart analysis was conducted in a university affiliated referral hospital. The participants were consecutive elderly patients, admitted with hyponatremia (< 135 mmol/L), and ultimately diagnosed as having SIADHS. We examined patient demographics, medical history, clinical presentation, laboratory and imaging studies, and hospital outcome. RESULTS: Of the 179 patients presenting with hyponatremia, 79 patients (44%) fulfilled the criteria for SIADHS; 73% of these patients were CDP and 27% were NHR (mean ages, 74.4 +/- 6.9 and 75.7 +/- 7.2 years, respectively). Most CDP complained of weakness and dizziness, while NHP presented with confusion, seizures and vomiting. Mean sodium levels and mean plasma osmolality values were similar in both groups, however, the number of patients with sodium levels < or = 121 mmol/L was significantly higher among NHR. The leading causes of SIADHS in both groups were medications, idiopathic form, and concurrent malignancies. In patients older than 81 years, idiopathic (50%) and drug-induced (20%) SIADHS were more frequent, compared with younger age groups. The overall in-hospital mortality rate was significantly higher in NHR as compared with CDP (p = 0.014), yet, it was similar in both groups once only patients with sodium levels of 121 mmo/L or lower were considered. CONCLUSIONS: While leading causes of SIADHS in community and nursing home residents are similar, there are marked differences in clinical presentation and outcome. This knowledge should help in identifying high-risk patients and taking appropriate measures.

Aged↗

Detection of change in shape: an advantage for concavities.

Shape representation was studied using a change detection task. Observers viewed two individual shapes in succession, either identical or one a slightly altered version of the other, and reported whether they detected a change. We found a dramatic advantage for concave compared to convex changes of equal magnitude. Observers were more accurate when a concavity along the contour was introduced, or removed, compared to a convexity. This result sheds light on the underlying representation of visual shape, and in particular the central role played by part-boundaries. Moreover, this finding shows how change detection methodology can serve as a useful tool in studying the specific form of visual representations.

Discrimination, Psychological↗

Visual comparisons within and between object parts: evidence for a single-part superiority effect.

Subjects judged whether two marks placed at different positions along a curved contour were physically the same. When targets were separated by a concave curvature extremum--corresponding to a part-boundary--decision latencies were longer than when they straddled an equally curved convex extremum, demonstrating a "single-part superiority effect". This difference increased with both stimulus duration and the magnitude of contour curvature. However, it disappeared when the global configuration was not consistent with a part-boundary interpretation, suggesting a critical role of global organization in part decomposition.

Form Perception↗

What is a visual object?

The concept of an 'object' plays a central role in cognitive science, particularly in vision, reasoning and conceptual development - but it has rarely been given a concrete formal definition. Here I argue that visual objects cannot be defined according to simple physical properties but can instead be understood in terms of the hierarchical organization of visual scene interpretations. Within the tree describing such a hierarchical description, certain nodes make natural candidates as the 'joints' between objects, representing division points between parts of the image that cohere internally but do not perceptually group with one another. Thus each subtree hanging from such a node corresponds to a single perceived 'object'. This formal definition accords with several intuitions about the way objects behave.

Journal Article↗

[Inflammatory Bowel diseases in the elderly].

Although often regarded as a disease of young adults, Inflammatory Bowel Disease occurs with greater frequency in the elderly than is generally anticipated. Due to the comorbidity in the elderly, the precise diagnosis of Inflammatory Bowel Disease is overlooked. There is a tendency for both Crohn's disease and ulcerative colitis to involve the distal colon in older patients. As a consequence, the disease is often milder and less complicated than in younger patients. The first wave of the disease in an older age group is characterized by a higher complication rate. The treatment modalities are the same as in the younger age groups. The disease is often overlooked and misdiagnosed. However, since it is a treatable condition, the clinician has to be more suspicious about it in the cases of prolonged diarrhea or other gastrointestinal symptoms in the elderly.

Adult↗

Is the treatment of hyperlipidemia as secondary prevention adequate in different age groups in Israel?

BACKGROUND: Treatment of hyperlipidemia is important for secondary prevention in patients suffering from coronary heart disease. It has been proven that "young elderly" (patients aged 65-75 years) can benefit from the treatment at least as much as younger patients. OBJECTIVE: To assess the adequacy of treatment as part of secondary prevention in "young elderly" and younger patients. METHODS: In this prospective study, 389 patients discharged from the hospital with the diagnosis of coronary heart disease were divided according to age groups. Data were collected regarding lipid profile examinations, dietary and drug therapy, and results of lipid profiles. RESULTS: Less than one-third of the patients achieved target low density lipoprotein levels. More patients in the older age group achieved the treatment goals. The goals were achieved despite the fact that the percentage of patients treated with lipid-lowering drugs was lower in the older age group. CONCLUSION: The percentage of patients treated for hyperlipidemia as part of a secondary prevention plan in Israel is similar to that in other developed countries. The fact that more "young elderly" patients achieve adequate lipid profiles compared to younger patients indicates that there is no age discrimination towards this patient group. The finding that less than one-third of the patients reach the treatment goals should prompt physicians to treat hyperlipidemia more aggressively.

Adult↗

Hypodermoclysis (subcutaneous infusion) effective mode of treatment of dehydration in long-term care patients.

Dehydration is associated with morbidity and mortality in frail elderly patients. Intravenous fluid administration in these patients is sometimes hard, especially in agitated patients. The purpose of this study was to review of 57 long-termed care patients received hypodermoclysis infusion on 118 different occasions during the 9 months. Data collection included: demographic data, functional and mental status, indication hypodermoclysis, duration of the infusion, type of solution, laboratory data, adverse effects, and outcome. The main reasons for initiation of the hypodermoclysis were either dehydration (64%) or febrile illness (21%). The average duration of infusions was 15.9 days and average daily volume was 1161 ml per day. After hydration by hypodermoclysis, in 77% of the patients, clinical improvement occurred manifested as general improvement (88%), cognitive status improvement (84%), and improved oral intake (81%). During the course of the study, failure of the treatment was observed in 12% of the patients, mortality of 11% was observed. Nobody developed signs of fluid overload. Local complications were reported in 12% of patients: local swelling (6/57), complain of local pain at site (3/57) and local inflammation (2/57). Hypodermoclysis is a safe, effective and suitable alternative to intravenous re-hydration in long-term care patients.

Aged↗

Water and sodium disturbances predict prognosis of acute disease in long term cared frail elderly.

Elderly patients are at increased risk for developing infections and fever. We aimed to investigate the incidence, causes and outcome of hypernatemia and hyponatremia among elderly long-term care patients with febrile illness. This is a prospective study conducted in a 110 beds, nursing department for dependent elderly in geriatric long-term care facility during 20 months period. Changes in plasma sodium concentrations were found in 48% (132/270) of the febrile illness: during the acute illness in 38% (102/270) of the events and during the follow-up period after acute febrile event, in 30% (59/198) of the events. Upper respiratory tract, bronchial, lung, and urinary tract infections were the most common causes for the fever. Hypernatremia was more prevalent on acute febrile illness (63%). Hyponatremia was more common before the febrile illness (10%) and during the follow-up period (69%). The most common causes of hypernatremia were inadequate hydration or correction (57%) and continuous diuretic treatment (38%). The most common causes of hyponatremia were: Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) (38%), incorrect hydration (19%), and continuous diuretic treatment (30%). During the study, 60% (28/47) of the patients died, and hypernatremia was detected in 82% (20/28). Disturbances in sodium concentrations were predictors of bad outcomes, related to the underlying diseases burden, and were not related to the magnitude of the changes in plasma sodium, time of its development, advanced age, gender and coexisting changes in plasma potassium level.

Acute Disease↗