Biomedical subjects

Jae-Bong Lee

Publications and source records attributed to Jae-Bong Lee.

6 recordsLinked to original sources

PubMed2004

Intralesional interferon alfa-2b treatment of keratoacanthomas.

BACKGROUND: Complete excision is not always easy when a keratoacanthoma is large or located in certain anatomic areas. An effective nonsurgical treatment would be desirable in such cases. OBJECTIVE: This was a pilot study of the effects of intralesional interferon alfa-2b in the treatment of rapidly growing keratoacanthomas. METHODS: A total of 4 large, rapidly growing keratoacanthomas, which were located on the lower lip, neck, and cheeks of the 4 different patients, were treated with intralesional interferon alfa-2b injection weekly. Serial photographs were taken to observe the course of responses. RESULTS: All lesions resolved completely in 5 to 7 weeks with acceptable cosmetic results. CONCLUSION: Intralesional interferon alfa-2b can be a treatment modality of these difficult lesions.

Aged↗

PubMed2004

Microarray-based expression analysis of human osteoblast-like cell response to anodized titanium surface.

An anodized surface significantly enhanced the adhesion of human osteoblast-like MG-63 cells to titanium. Using cDNA microarray analysis, five genes were differentially expressed while the rest remained unaltered. The results demonstrated that the anodized surface enhances cellular adhesion without significantly affecting the pattern of gene expression.

Biocompatible Materials↗

PubMed2004

Multiple basal cell carcinomas arising in a port-wine stain with a remote history of therapeutic irradiation.

The coexistence of a basal cell carcinoma and a port-wine stain is a very rare condition that may be associated with previous treatments. We present a case of multiple basal cell carcinomas developing within the boundaries of a port-wine stain, which had been treated with a tholium X and argon laser. Our case suggests that port-wine stains which were previously treated with irradiation or argon laser should be examined carefully and regularly by both physician and patient, because they may hide basal cell carcinomas.

Biopsy, Needle↗

PubMed2004

A case of foul genital odor treated with botulinum toxin A.

BACKGROUND: Genital odor is an uncommon condition characterized by an offensive and malodorous smell in the genital area. Although the etiology of foul genital odor is multifactorial, an important cause is sweat secretion and decomposition of sweat components by bacteria. Different methods are effective in reducing body odor secondary to bromhidrosis. Conservative methods only act for a short period of time, and more invasive surgical methods carry risk of complications or are inapplicable for the genital region. METHODS: A patient with localized foul odor in the genital hair bearing area was treated with botulinum toxin A. RESULTS: Botulinum toxin A was effective in creating an odorless and anhydrous response in the genital region, and no major adverse effects were noted during a follow-up of 9 months after injection. CONCLUSION: Local injection of botulinum toxin A appears to be a useful treatment for foul genital odor related to sweat glands activity.

Adult↗

PubMed2003

A case of porocarcinoma from pre-existing hidroacanthoma simplex: need of early excision for hidroacanthoma simplex?

BACKGROUND: Hidroacanthoma simplex (HAS) is an uncommon eccrine neoplasm of the skin. It is a benign neoplasm, but some cases of malignant change were reported in the literature. OBJECTIVE: To describe a rare case of porocarcinoma in a relatively short period from pre-existing HAS on the abdomen. METHODS: Wide local excision was performed on this neoplasm. RESULTS: There was no recurrence for 72 months after wide excision. CONCLUSION. : We recommend an early excision and careful attention in the case of HAS because of its potential malignant change.

Abdomen↗

PubMedDate not supplied

Successful treatment of localized cutaneous infection caused by Mycobacterium scrofulaceum with clarithromycin.

Cutaneous infection arising from Mycobacterium scrofulaceum, a nontuberculous mycobacteria, has rarely been reported, and most of the reported infections were disseminated forms in patients with AIDS or other immunocompromising illness. We describe an occurrence of localized mycobacterial skin infection caused by M. scrofulaceum in a previously healthy child that manifested as a red nodule on the cheek. A biopsy specimen of the lesion demonstrated granulomatous infiltration in the dermis. M. scrofulaceum was isolated from culture of a tissue specimen. Polymerase chain reaction amplified specific fragments for M. scrofulaceum. The patient was treated successfully with clarithromycin as monotherapy for 6 months, leading to complete healing without recurrence during a follow-up period of 2 years.

Anti-Bacterial Agents↗