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Biomedical subjects

Jaime Gunnoe

Publications and source records attributed to Jaime Gunnoe.

3 recordsLinked to original sources

Long-term effects of connective tissue cancer treatment.

In 1999, we began a study to assess the long-term effect of connective tissue cancer treatment on clinical, social, and psychologic aspects of the lives of surviving patients. A specially designed computer program generated an 85-item questionnaire, which was sent to more than 2000 patients with malignant bone and soft tissue neoplasms. Twelve hundred forty-four patients responded. The data were entered into a computer system and were correlated with the clinical information already contained in the system for the individual patients. Although there are many possible uses for these data, we chose to do a study comparing the lifestyle and physical and sociologic problems for 144 patients treated with chemotherapy and surgery for high-grade osteosarcoma against a control population consisting of 61 patients treated surgically for benign giant cell tumors of bone. The data show a remarkable degree of compensation on the part of the patients with the malignant tumors in terms of some problems but some significant differences particularly in physical status and functional limitations.

Activities of Daily Living↗

Gender and culture differences in touching behavior.

The authors used gender and culture to examine the theory that touching behavior is an expression of dominance. Participants were 120 men and women from Italy, the Czech Republic, and the United States. The authors examined both hand touches and nonhand touches. For hand touches, there was a significant gender-by-culture interaction in that Czech men as a group touched more than any of the other groups. For nonhand touches, Czech and Italian women and Italian men as groups touched significantly more than any of the other groups. Taken in cultural context, these results seem to support the dominance theory for touches with the hand but not for nonhand touches. The authors discussed implications and future directions.

Adult↗

Comparison of quality of life after amputation or limb salvage.

In the past, amputation was the standard method of treatment for patients with sarcomas in the extremity but limb-sparing procedures now are much more frequent. A computerized questionnaire automatically adjusted for gender, age, diagnosis, site, and treatment was sent to 2200 patients with high-grade sarcomas who had been treated during the past 25 years. Using the data, it was possible to study and compare the response from 66 patients who had an amputation and 342 patients with a limb-sparing procedure for a lower extremity neoplasm. More males had an amputation, but no differences were observed in the ages of the two groups. The outcomes for the two groups were similar. Patients who had limb-sparing procedures did not have a significant improvement in the ability to ambulate, climb stairs, drive a car, or be employed. More of the patients with amputations required walking aids and participated in sports activities at almost the same rate as the patients who had limb-sparing procedures. Patients who had amputations had no more anxiety, drug-dependence, depression, sleep problems, or limitation of sexual performance than patients who retained their limbs. The patients with amputations had more children and fewer menstrual problems; however, they were far less satisfied with their status at early ages than at later periods in their lives.

Adolescent↗